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New HIV infections and transmission rate in the U.S. drop, but fall short of NHAS goals

The number of new HIV infections and the transmission rate in the United States dropped by 11 and 17 percent, respectively, between 2010 and 2015, but fell short of the goals put forth by President Obama's U.S. National HIV/AIDS Strategy (NHAS), researchers from the Perelman School of Medicine at the University of Pennsylvania and Johns Hopkins Bloomberg School of Public Health reported this week in the journal AIDS and Behavior.

4 May 2016

Biomedical researcher wins 2016 Gutenberg Research Award for work on programmed cell death

The Gutenberg Research College of Johannes Gutenberg University Mainz has chosen to give the 2016 Gutenberg Research Award to American biomedical researcher Dr. Vishva Dixit for his groundbreaking work in the field of programmed cell death.

4 May 2016

NSCLC MAGE-A3 immunotherapy development halted

Disease-free survival is not prolonged with adjuvant MAGE-A3 immunotherapy in patients with surgically resected non-small-cell lung cancer, according to a placebo-controlled trial.

4 May 2016

Cerebellar not cerebral atrophy predicts poor anti-NMDAR encephalitis outcome

Diffuse cerebral atrophy in patients with anti-N-methyl-D-aspartate receptor encephalitis does not necessarily mean irreversible brain damage, whereas progressive cerebellar atrophy may indicate a poor long-term prognosis, researchers report.

4 May 2016

Total cessation of GnRH production by hypothalamic neurons can lead to infertility

Individual small RNAs are responsible for controlling the expression of gonadoliberin or GnRH (Gonadotropin-Releasing Hormone), a neurohormone that controls sexual maturation, the appearance of puberty, and fertility in adults.

3 May 2016

Important changes in social lives of older adults indicate cognitive decline

Small changes in the social lives of older people are early red flags showing that their thought processes and brain functioning could be on the decline. This is according to Ashwin Kotwal of Brigham and Women's Hospital in the US, who led a study¹ in the Journal of General Internal Medicine, published by Springer.

3 May 2016

Understanding effects of freeze-thawing, intravenous delivery on MSC function

Before the therapeutic potential of using human tissue-derived mesenchymal stromal cells (MSC) to treat immune and degenerative diseases can be fully determined, the effects of freeze-thawing and intravenous delivery on MSC function must be understood.

3 May 2016

New investigational inhibitor JQEZ5 can block specific molecular malfunctions driving cancer

In a step forward in the push for targeted treatments that can block the specific molecular malfunctions driving cancer, University of North Carolina Lineberger Comprehensive Cancer Center researchers have demonstrated how a genetic mutation can drive the most common type of lymphoma as well as melanoma, the deadliest form of skin cancer.

3 May 2016

Combination of existing chemotherapy drugs can reduce breast cancer stem cells, improve survival

Two existing chemotherapy drugs appear to be a powerful pair in targeting errant stem cells that are making breast cancer and enabling its spread and recurrence, scientists report.

3 May 2016

Self-reported care delays linked to long waiting times in VA health coverage system

Military veterans are more likely to report delays in seeking necessary healthcare, compared to the US general population, reports a study in the Journal of Public Health Management and Practice. The journal is published by Wolters Kluwer.

3 May 2016

Hepatitis B virus screening for Asian American adults can help prevent onset of liver diseases

A community-based hepatitis B virus screening effort led by UC Davis researchers found that targeted outreach to Asian American populations can identify groups at high risk for infection and direct them to appropriate follow-up care to help prevent the onset of liver diseases, including cancer.

3 May 2016

Study reveals long-term health-related quality of life in bariatric surgery patients

Significant improvement in health-related quality of life was reported by patients 12-14 years after undergoing an uncommon form of bariatric surgery at one U.S. medical center. Follow-up of the 27 patients who underwent biliary pancreatic diversion surgery with duodenal switch (BPD-DS) by the same surgeon is described in an article in Bariatric Surgical Practice and Patient Care, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available free for download until June 2, 2016.

3 May 2016

Influence of psychiatric comorbidities on all-cause readmissions following elective spine surgery

Winner of the Robert Florin Resident Award, Owoicho Adogwa, MD, presented his research, Association Between Baseline Affective Disorders and 30-day Readmission Rates in Patients Undergoing Elective Spine Surgery, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

3 May 2016

Study opens door for new opportunities in finding antidotes to nerve agent sarin

The nerve agent sarin causes a deadly overstimulation of the nervous system that can be stopped if treated with an antidote within minutes of poisoning. Today, a ground-breaking study has been published in PNAS, which in detail describes how such a drug works. Researchers at the Swedish Defence Research Agency, Umea University and in Germany are behind the study.

3 May 2016

High-intensity exercise, group activity reduce depression among older dementia patients

Both a high-intensity functional exercise programme and a non-exercise group activity, conducted among older care facility residents with dementia, reduced high levels of depressive symptoms. However, exercise had no superior effect on depression, according to a dissertation from Umea University.

3 May 2016

International researchers redefine scientifc concept of obesity

Researchers have determined that obesity involves excessive body weight (including fat and muscle) for a given height and not just excess body fat as was formerly believed.

3 May 2016

Researchers discover new function of genes in Fanconi anemia pathway

Researchers from UT Southwestern Medical Center have identified an important new function of genes in the Fanconi anemia pathway - a finding that could have implications for development of new therapies to treat this disorder and some cancers.

3 May 2016

Xiao procedure lacks efficacy for bladder control in children

Researchers at Johns Hopkins All Children's Hospital report the results of a double-blinded randomized controlled trial of the "Xiao procedure" in children with spina bifida.

3 May 2016

Flu vaccinations for pregnant women reduce newborn’s influenza risk during first six months of life

Babies whose moms get flu vaccinations while pregnant have a significantly reduced risk of acquiring influenza during their first six months of life, a new study shows, leading the authors to declare that the need for getting more pregnant women immunized is a public health priority.

3 May 2016

Community-based social groups could support people with early-onset dementia

Community-based social groups could play a crucial role in empowering people with early-onset dementia, according to new UBC research.

3 May 2016

Medical Research News

New HIV infections and transmission rate in the U.S. drop, but fall short of NHAS goals

Biomedical researcher wins 2016 Gutenberg Research Award for work on programmed cell death

NSCLC MAGE-A3 immunotherapy development halted

Cerebellar not cerebral atrophy predicts poor anti-NMDAR encephalitis outcome

Total cessation of GnRH production by hypothalamic neurons can lead to infertility

Important changes in social lives of older adults indicate cognitive decline

Understanding effects of freeze-thawing, intravenous delivery on MSC function

New investigational inhibitor JQEZ5 can block specific molecular malfunctions driving cancer

Combination of existing chemotherapy drugs can reduce breast cancer stem cells, improve survival

Self-reported care delays linked to long waiting times in VA health coverage system

Hepatitis B virus screening for Asian American adults can help prevent onset of liver diseases

Study reveals long-term health-related quality of life in bariatric surgery patients

Influence of psychiatric comorbidities on all-cause readmissions following elective spine surgery

Study opens door for new opportunities in finding antidotes to nerve agent sarin

High-intensity exercise, group activity reduce depression among older dementia patients

International researchers redefine scientifc concept of obesity

Researchers discover new function of genes in Fanconi anemia pathway

Xiao procedure lacks efficacy for bladder control in children

Flu vaccinations for pregnant women reduce newborn’s influenza risk during first six months of life

Community-based social groups could support people with early-onset dementia

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