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Study finds difference between results from IHC and quantitative molecular techniques

The cause of type 1 diabetes remains unknown. Several studies using immunohistochemistry (IHC) have independently reported hyperexpression of human leukocyte antigen (HLA) class I on pancreatic islet cells in young patients with recent-onset type 1 diabetes. Investigators have therefore suggested that HLA hyperexpression may be an important first step in the development of type 1 diabetes.

12 Jan 2015

Pathologists use ProExC antibody cocktail to determine tumor recurrence

Partnering with head and neck surgeons, pathologists at Dartmouth Hitchcock Medical Center's Norris Cotton Cancer Center developed a new use for an old test to determine if a patient's cancer is recurring, or if the biopsy shows benign inflammation of mucosal tissues. In Pathology - Research and Practice, lead author Candice C. Black, DO explained how her team confirmed the utility of ProExC, an existing antibody cocktail commonly used for pathology tests of the uterine cervix.

12 Jan 2015

Radon linked to lung cancer risk in nonsmokers

Each year, radon kills more people than home fires, drowning, falls or drunk driving. It is the number one cause of lung cancer in nonsmokers, taking some 21,000 lives annually.

12 Jan 2015

Injectable hormonal contraceptive appears to increase HIV risk in women

Women using depot medroxyprogesterone acetate (DMPA), commonly known as Depo-Provera or the birth control shot, have a moderately increased risk of becoming infected with HIV, a large meta-analysis of 12 studies involving more than 39 500 women published in The Lancet Infectious Diseases has found. Other forms of hormonal contraception, including oral contraceptive pills, do not appear to increase this risk.

12 Jan 2015

Family history could help physicians identify prostate cancer risk

A discovery by researchers at Huntsman Cancer Institute shows that looking at whether a man's uncles and great-grandparents, among other second- and third-degree relatives, had prostate cancer could be as important as looking at whether his father had prostate cancer. A more complete family history would give physicians a new tool to decide whether or not a PSA test was appropriate.

12 Jan 2015

Biogen Idec, Columbia University Medical Center form $30 million genomics research alliance

Biogen Idec and Columbia University Medical Center have formed a $30 million strategic alliance to conduct genetics discovery research on the underlying causes of disease and to identify new treatment approaches. As part of this agreement, a sequencing and analysis facility and shared postdoctoral program will be established at Columbia to support collaborative genetics studies.

11 Jan 2015

LJI researcher awarded $1.6 million grant to study factors that trigger onset of type 1 diabetes

The American Diabetes Association has awarded La Jolla Institute researcher Stephanie Stanford, Ph.D., a $1.6 million grant to investigate the genetic and environmental factors that trigger the onset of type 1 diabetes.

11 Jan 2015

Mayo Clinic study dispels myth that cancer biopsies cause cancer to spread

A study of more than 2,000 patients by researchers at Mayo Clinic's campus in Jacksonville, Florida, has dispelled the myth that cancer biopsies cause cancer to spread. In the Jan. 9 online issue of Gut, they show that patients who received a biopsy had a better outcome and longer survival than patients who did not have a biopsy.

11 Jan 2015

New UCLA study sheds light on why some people develop PTSD

Why do some people develop post-traumatic stress disorder (PTSD) while others who suffered the same ordeal do not? A new UCLA discovery may shed light on the answer.

11 Jan 2015

Simple training exercise of catching a medicine ball may help prevent falls in the elderly

The simple training exercise of catching a weighted medicine ball can improve balance and may help prevent falls in the elderly, according to research at the University of Illinois at Chicago.

11 Jan 2015

A good night's sleep linked to better academic performance in children

Making sure school-aged kids get to sleep at a regular hour is often a struggle for parents. But a study by researchers at McGill University and the Douglas Mental Health University Institute in Montreal suggests it's well worth the effort: the researchers found that a good night's sleep is linked to better performance in math and languages - subjects that are powerful predictors of later learning and academic success.

9 Jan 2015

Personal gender identity of every human being is reflected in the structure of brain networks

Our sense of belonging to the male or female gender is an inherent component of the human identity perception. As a general rule, gender identity and physical sex coincide. If this is not the case, one refers to trans-identity or transsexuality. In a current study, brain researcher Georg S. Kanz of the University Clinic for Psychiatry and Psychotherapy of the MedUni Vienna was able to demonstrate that the very personal gender identity of every human being is reflected and verifiable in the cross-links between brain regions.

9 Jan 2015

Yeast-eating gut bacteria can help battle bowel problems and autoimmune diseases

Human gut bacteria that feast on the yeast contained in fermented foods like bread and beer provides clues to new treatments for people suffering from bowel diseases.

9 Jan 2015

Sustained quality improvement changes in ICU benefits both patients and health care facility

In a pre- and post-evaluation study, Johns Hopkins Medicine researchers found that quality improvement changes made in an intensive care unit (ICU) were still in practice five years later — benefiting both patients and the health care facility. Those changes included new protocols for treating critically ill patients by encouraging early physical therapy in the ICU.

9 Jan 2015

CHLA scientists grow tissue-engineered small intestine from human cells

A new study by researchers at Children's Hospital Los Angeles has shown that tissue-engineered small intestine grown from human cells replicates key aspects of a functioning human intestine. The tissue-engineered small intestine they developed contains important elements of the mucosal lining and support structures, including the ability to absorb sugars, and even tiny or ultra-structural components like cellular connections.

9 Jan 2015

Increased UV radiation can affect human fertility, new NTNU study finds

A new study from the Norwegian University of Science and Technology shows that increased UV radiation can have an effect on human fertility over generations.

9 Jan 2015

Latest wearable tracking devices alone may not change health behavior, say Penn researchers

New Year's weight loss resolutions are in full swing, but despite all the hype about the latest wearable tracking devices, there's little evidence that this technology alone can change behavior and improve health for those that need it most, according to a new online-first viewpoint piece in JAMA.

9 Jan 2015

Man-made insulin nasal spray may improve memory in adults with Alzheimer's-related dementia

A man-made form of insulin delivered by nasal spray may improve working memory and other mental capabilities in adults with mild cognitive impairment and Alzheimer's disease dementia, according to a pilot study led by researchers at Wake Forest Baptist Medical Center.

9 Jan 2015

Researchers to explore physical, psychological effects of ultra-endurance running

In the upcoming Race Across USA, ultra-endurance athletes will run a marathon a day as they cover 3,080 miles from California to Maryland.

8 Jan 2015

Exposure to nanoparticles can play major role in development of cardiovascular diseases

Nanoparticles, extremely tiny particles measured in billionths of a meter, are increasingly everywhere, and especially in biomedical products. Their toxicity has been researched in general terms, but now a team of Israeli scientists has for the first time found that exposure nanoparticles (NPs) of silicon dioxide (SiO2) can play a major role in the development of cardiovascular diseases when the NP cross tissue and cellular barriers and also find their way into the circulatory system.

8 Jan 2015

Medical Research News

Study finds difference between results from IHC and quantitative molecular techniques

Pathologists use ProExC antibody cocktail to determine tumor recurrence

Radon linked to lung cancer risk in nonsmokers

Injectable hormonal contraceptive appears to increase HIV risk in women

Family history could help physicians identify prostate cancer risk

Biogen Idec, Columbia University Medical Center form $30 million genomics research alliance

LJI researcher awarded $1.6 million grant to study factors that trigger onset of type 1 diabetes

Mayo Clinic study dispels myth that cancer biopsies cause cancer to spread

New UCLA study sheds light on why some people develop PTSD

Simple training exercise of catching a medicine ball may help prevent falls in the elderly

A good night's sleep linked to better academic performance in children

Personal gender identity of every human being is reflected in the structure of brain networks

Yeast-eating gut bacteria can help battle bowel problems and autoimmune diseases

Sustained quality improvement changes in ICU benefits both patients and health care facility

CHLA scientists grow tissue-engineered small intestine from human cells

Increased UV radiation can affect human fertility, new NTNU study finds

Latest wearable tracking devices alone may not change health behavior, say Penn researchers

Man-made insulin nasal spray may improve memory in adults with Alzheimer's-related dementia

Researchers to explore physical, psychological effects of ultra-endurance running

Exposure to nanoparticles can play major role in development of cardiovascular diseases

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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