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Drugs designed to curb Rac1 signaling pathway may help relieve inflammatory pain in sufferers

New research uncovers a cascade of reactions within nerve cells that relay sensations of pain associated with inflammation. The findings, which are published in the British Journal of Pharmacology, indicate that drugs designed to curb this pathway may help relieve inflammatory pain in sufferers.

11 Feb 2016

Neutrophils promote cardiac repair

Following an acute heart attack, immune cells called neutrophils coordinate an inflammatory response which can exacerbate the damage to the organ. Now researchers from Ludwig-Maximilians-Universitaet in Munich have shown that neutrophils also promote cardiac repair.

11 Feb 2016

Dementia incidence highest in African Americans, lowest in Asian Americans

The first study to look at dementia risk in a population representing the diversity of the United States finds dementia incidence to be highest in African Americans and lowest in Asian Americans. The rate of occurrence of dementia in African Americans was found to be 65 percent higher than Asian Americans.

10 Feb 2016

Five researchers named winners of 2016 Elsevier Foundation Awards

Five researchers have been named winners of the 2016 Elsevier Foundation Awards for Early Career Women Scientists in the Developing World, in recognition of research that has strong potential health and economic benefits.

10 Feb 2016

Fasudil improves memory in rats, promotes degradation of toxic tau in the eyes of fruit flies

Could a kinase inhibitor some doctors prescribe to keep blood flowing after brain surgery be used to treat neurodegeneration? New research suggests it might be worth exploring the question.

10 Feb 2016

Cranberry capsules more effective in lowering UTI risk than juice

A UTI is an infection in any part of the urinary system, kidneys, bladder or urethra. They are more common in women and affect more than 3 million Americans per year. Many in the population will turn to sipping on a cranberry juice cocktail to alleviate their symptoms, but, according to a Texas A&M Health Science Center urologist, drinking cranberry juice to treat a UTI is little more than an old wives' tale.

10 Feb 2016

Pediatric ALL patients treated with chemotherapy alone at risk for neurocognitive deficits

Pediatric acute lymphoblastic leukemia (ALL) patients treated with chemotherapy alone remain at risk for attention and learning problems that persist after treatment ends, according to St. Jude Children's Research Hospital investigators.

10 Feb 2016

Study sheds light on role of red raspberries in metabolically-based chronic diseases

Components in red raspberries may have anti-inflammatory, anti-oxidative and metabolic stabilizing activity, according to a comprehensive review of the available scientific literature published in the January issue of Advances in Nutrition.

10 Feb 2016

BMJ, UCSF team up to provide self-study online modules for healthcare researchers

BMJ, a global healthcare knowledge provider, has joined forces with the University of California, San Francisco, a world leader in biomedical research, to provide self-study online modules for doctors and healthcare researchers to develop their research skills and become published authors.

10 Feb 2016

LMU researchers identify new drug target for atherosclerosis

The enzyme Dicer processes RNA transcripts, cutting them into short segments that regulate the synthesis of specific proteins. An Ludwig-Maximilians-Universitaet in Munich team has shown that Dicer promotes the development of atherosclerosis, thus identifying a new drug target.

10 Feb 2016

Minimum legal drinking age legislation can have major impact on young drivers in Canada

A new study led by a Northern Medical Program (NMP) researcher shows that alcohol-impaired driving crimes spike immediately after the minimum legal drinking age (MLDA) is reached, indicating that minimum legal drinking age legislation in Canada can have a major impact on young drivers.

10 Feb 2016

Helpful protein can change genetic sequence of normal cells and make mutations that cause cancers

Washington State University researchers have determined how a protein that helps cells fight viruses can also cause genetic mutations that lead to cancer.

10 Feb 2016

2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

A first-ever interlaboratory study of four versions of a therapeutic protein drug—all manufactured from living cells—reports that an established analytical tool akin to magnetic resonance imaging reliably assessed the atomic structures of the biologically similar products, yielding the equivalent of a fingerprint for each.

10 Feb 2016

Muscle protein titin plays vital role in Frank-Starling mechanism

Researchers at Illinois Institute of Technology and Loyola University have discovered new clues in the 100-year-old mystery of the Frank-Starling law of the heart: What makes the heart contract more strongly at longer lengths given the same level of calcium activation?

10 Feb 2016

Internet-based social interventions important for healthy ageing

Meaningful and Internet-based activities promote experiences of participation in society and are important for healthy ageing. In a new dissertation at Umeå University in Sweden, occupational therapists are shown to promote participation, reduce experiences of loneliness and strengthen seniors' social network using an Internet-based intervention programme.

10 Feb 2016

Diet containing unsaturated fats positively impacts weight loss and heart health markers

A new study published in the Journal of the American Heart Association found that a diet containing unsaturated fats, such as those found in walnuts and olive oil, has similar weight loss effects as a lower fat, higher-carbohydrate diet.

10 Feb 2016

Simple change in diet could boost vitamin D levels for people suffering from Type 2 diabetes

A simple change in diet could boost vitamin D levels for millions of Americans suffering from Type 2 diabetes, according to new research from Iowa State University published in the Journal of Agricultural and Food Chemistry.

10 Feb 2016

Researchers sequence genetic blueprint of Lyme-disease-spreading tick

Researchers have sequenced the genetic blueprint of one of the most prolific pathogen-transmitting agents on the planet - the Lyme-disease-spreading tick (Ixodes scapularis) that bites humans. The findings could lead to advances in not only disrupting the tick's capacity to spread diseases but also in eradicating the pest.

10 Feb 2016

Barley can help reduce blood sugar levels and diabetes risk

A recent study from Lund University in Sweden shows that barley can rapidly improve people's health by reducing blood sugar levels and risk for diabetes. The secret lies in the special mixture of dietary fibres found in barley, which can also help reduce people's appetite and risk for cardiovascular disease.

10 Feb 2016

Penn investigators devise new method to map 'transcriptome'

A new way of mapping the "transcriptome" -- the collection of RNA read-outs that are expressed by a cell's active genes -- has been devised by researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Feb 2016

Medical Research News

Drugs designed to curb Rac1 signaling pathway may help relieve inflammatory pain in sufferers

Neutrophils promote cardiac repair

Dementia incidence highest in African Americans, lowest in Asian Americans

Five researchers named winners of 2016 Elsevier Foundation Awards

Fasudil improves memory in rats, promotes degradation of toxic tau in the eyes of fruit flies

Cranberry capsules more effective in lowering UTI risk than juice

Pediatric ALL patients treated with chemotherapy alone at risk for neurocognitive deficits

Study sheds light on role of red raspberries in metabolically-based chronic diseases

BMJ, UCSF team up to provide self-study online modules for healthcare researchers

LMU researchers identify new drug target for atherosclerosis

Minimum legal drinking age legislation can have major impact on young drivers in Canada

Helpful protein can change genetic sequence of normal cells and make mutations that cause cancers

2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

Muscle protein titin plays vital role in Frank-Starling mechanism

Internet-based social interventions important for healthy ageing

Diet containing unsaturated fats positively impacts weight loss and heart health markers

Simple change in diet could boost vitamin D levels for people suffering from Type 2 diabetes

Researchers sequence genetic blueprint of Lyme-disease-spreading tick

Barley can help reduce blood sugar levels and diabetes risk

Penn investigators devise new method to map 'transcriptome'

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