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New AI tool maps millions of CD8+ T cells to advance disease research

The scAtlasVAE model integrates scRNA-seq data to create a CD8+ T cell atlas, enhancing understanding of immune responses in inflammation and cancer.

4 Dec 2024

Childhood exposure to leaded gasoline linked to mental illness and personality changes

New research published in the Journal of Child Psychology and Psychiatry indicates that childhood lead exposure, which peaked from 1960 through 1990 in most industrialized countries due to the use of lead in gasoline, has negatively impacted mental health and likely caused many cases of mental illness and altered personality.

4 Dec 2024

Study reveals non-invasive technique for early detection of sepsis

Clinicians lack methods for early detection of sepsis, a dysregulated response to infection that can result in life-threatening organ failure if treatment is delayed.

4 Dec 2024

Long Covid in teenagers shows significant improvement within two years

Most young people who were confirmed to have long Covid three months after a positive PCR test had recovered within 24 months, finds a new study led by UCL researchers.

4 Dec 2024

Cancer therapy may raise heart attack and stroke risks by disrupting immune regulation in arteries

Immune checkpoint inhibitors may heighten cardiovascular risks by altering immune interactions in atherosclerotic plaques, particularly in diabetic patients.

4 Dec 2024

Study shows connection between ultra-processed foods and intramuscular fat

A diet high in ultra-processed foods is associated with higher amounts of fat stored inside thigh muscles, regardless of the amount of calories consumed or level of physical activity, according to a study being presented today at the annual meeting of the Radiological Society of North America (RSNA).

4 Dec 2024

Mexican American women show highest rates of medication nonadherence after stroke

Women who have had a stroke may be less likely than men to take medications to prevent a second stroke, with Mexican American women reporting the highest rates of nonadherence, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

4 Dec 2024

Transgender women face significantly more injuries than cisgender women

A new study found that injury rates among transgender women are significantly higher than injuries among cisgender women, based on radiological imaging.

4 Dec 2024

Exploring the potential of MSCs in cancer therapy

A new review was published in Oncotarget's Volume 15 on November 22, 2024, entitled "Mesenchymal stem cells – the secret agents of cancer immunotherapy: Promises, challenges, and surprising twists."

4 Dec 2024

Disrupted sleep-wake rhythms linked to liver disease progression

The prevalence of MASLD (metabolic dysfunction-associated steatotic liver disease) is exploding in most regions of the world, boosted by increased obesity and sedentary lifestyles. MASLD (formerly known as non-alcoholic fatty liver disease) is already the most common liver disorder: it affects 30% of adults and between 7% and 14% of children and adolescents, and this prevalence is predicted to rise to more than 55% of adults by 2040.

4 Dec 2024

US census data reveal socioeconomic drivers of air pollution-related cancer risks

New research builds on scientific understanding of how air pollution and cancer risk are distributed throughout the U.S. Air pollution, often resulting from industrial or vehicle emissions, can travel for hundreds of miles and impact the health of communities through higher rates of asthma, respiratory infections, stroke, and lung cancer.

4 Dec 2024

Study highlights gaps in current health programs for truck drivers

It might seem out of place on the side of a highway, but purpose-built exercise equipment installed at truck stops across Australia could be just the thing to encourage truck drivers to take a break and take control of their health and wellbeing.

4 Dec 2024

Spider brain studies lead to breakthrough in understanding human brain diseases

Researchers from Saint Michael's College and the University of Vermont have made a groundbreaking new discovery that provides a better understanding of how Alzheimer's disease develops in the human brain.

4 Dec 2024

AI in medicine: Revolutionary tools, uncertain results

AI decision-making systems show promise but lack consistent evidence for improving patient-relevant outcomes like mortality and quality of life. Rigorous harm-benefit assessments and transparency are needed for safe integration into healthcare.

3 Dec 2024

Type 2 diabetes doubles infection-related mortality and exposes gaps in health reporting

People with type 2 diabetes face a significantly higher risk of infection-related deaths, particularly in younger age groups, with infections accounting for 13% of deaths compared to 1.2% in conventional records.

3 Dec 2024

Dual use of vapes and cigarettes hinders smoking cessation

People who use both vapes and cigarettes are less likely to quit compared to people who only smoke or only vape, according to a study published today (Wednesday) in ERJ Open Research.

3 Dec 2024

Holistic lifestyle interventions outshine drugs in preventing cardiometabolic diseases

Comprehensive lifestyle interventions prevent cardiometabolic diseases effectively but face challenges in routine care and require supportive policies for lasting impact.

3 Dec 2024

Study shows lasting benefits of anti-hormonal therapy in postmenopausal women

Today, women with estrogen-sensitive breast cancer receive anti-hormonal therapy. Researchers now show that postmenopausal women with low-risk tumors have a long-term benefit for at least 20 years, while the benefit was more short-term for younger women with similar tumor characteristics who had not yet gone through the menopause.

3 Dec 2024

Short bursts of vigorous activity may lower cardiovascular risk in women

Short bursts of incidental vigorous physical exertion, lasting less than a minute each, may almost halve the risk of a major cardiovascular event, such as heart attack or heart failure among women who don't exercise regularly, finds research published online in the British Journal of Sports Medicine.

3 Dec 2024

Behavioral chaos in Alzheimer’s disease mice decoded by machine learning

Researchers use machine learning to identify behavioral disruptions in Alzheimer’s disease mouse models, highlighting a potential therapeutic target in fibrinogen-microglia interactions.

3 Dec 2024