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Two genetic variants linked to Alzheimer's trigger microglial inflammation in females

Weill Cornell Medicine investigators have found that two genetic variants that confer high risk of Alzheimer's disease (AD) together trigger a harmful inflammatory response in the brain's immune cells, particularly in females, in a preclinical model.

30 Sep 2024

New genetic syndrome bridges the gap between neurodevelopmental and neurodegenerative disorders

In a landmark discovery, researchers from the University of Antioquia have identified a new genetic syndrome that bridges the gap between neurodevelopmental disorders and neurodegenerative diseases.

30 Sep 2024

Falls linked to increased risk of dementia in older adults

In a retrospective study of Medicare claims data, researchers found dementia was more frequently diagnosed within one year of a fall compared to other types of injuries.

30 Sep 2024

Study explores whether certain brain proteins may play a role in Alzheimer's development

With a four-year, $3.3 million grant from the National Institutes of Health (NIH), researchers from Case Western Reserve University will study whether certain brain proteins may play a role in the development of Alzheimer's disease.

30 Sep 2024

New insights into astrocytes offer hope for Alzheimer's treatment

A research team led by Dr. Hoon Ryu from the Korea Institute of Science and Technology (KIST, President Sang-Rok Oh) Brain Disease Research Group, in collaboration with Director Justin C. Lee of the Institute for Basic Science (IBS, President Do-Young Noh) and Professor Junghee Lee from Boston University Chobanian & Avedisian School of Medicine, has uncovered a new mechanism involving astrocytes for treating Alzheimer's disease (AD) and proposed a novel therapeutic target.

30 Sep 2024

Discovery of antibodies that boost complement activation against K. pneumoniae

Researchers investigate antibody-dependent complement activation during Klebsiella pneumoniae infection.

30 Sep 2024

Regulating iron overload: Liraglutide's potential benefits

Researchers assess the role of liraglutide in regulating iron metabolism in a mouse model of hereditary hemochromatosis.

30 Sep 2024

Researchers uncover genetic link between bipolar disorder type I and epilepsy

A team of researchers from the Chinese Academy of Sciences has uncovered compelling evidence of a genetic link between bipolar disorder type I (BD-I) and epilepsy, potentially revolutionizing our understanding of these complex neuropsychiatric conditions.

30 Sep 2024

$Scientists discover potential new treatment for heart failure with preserved ejection fraction$

Scientists discover potential new treatment for heart failure with preserved ejection fraction

Duke-NUS scientists and their collaborators have discovered a potential new treatment for heart failure with preserved ejection fraction (HFpEF), a type of heart disease that is notoriously difficult to treat.

30 Sep 2024

Study links COVID-19 to increased risk of acute kidney disorders

Researchers from West China Hospital, Sichuan University, have conducted a study revealing a significant association between COVID-19 and acute kidney disorders (AKD), including acute kidney injury (AKI), that varies over time.

30 Sep 2024

Autoimmune diseases more common in women who stop ovulating before 40

The study finds a significant correlation between premature ovarian insufficiency and autoimmune diseases, urging further investigation into prevention methods.

30 Sep 2024

Phytoene increases lifespan, reduces oxidative stress and amyloid toxicity

Research indicates phytoene from microalgae protects against oxidative stress and beta-amyloid toxicity, suggesting its potential in promoting healthy aging.

30 Sep 2024

Over 80% of women are iron deficient by their third trimester

Iron deficiency is prevalent among pregnant women, impacting health outcomes. This study emphasizes the importance of monitoring and nutrition during pregnancy.

30 Sep 2024

The consumption of flavonoid-rich foods was associated with a reduced risk of NAFLD among middle-aged adults

Research indicates that high flavonoid intake is linked to a lower risk of NAFLD, with apples and tea showing significant protective effects on liver health.

30 Sep 2024

Owlstone Medical launches Breath Biopsy VOC Atlas® to unlock disease biomarkers in human breath

The Breath Biopsy VOC Atlas offers a comprehensive catalog of volatile organic compounds, enhancing understanding of breath biomarkers in health and disease.

From Owlstone Medical Ltd 30 Sep 2024

Researchers identify a protein that recharges T cells for long-lasting cancer remission

Research shows Fc–IL-4 revitalizes exhausted CD8+ T cells, boosting antitumor responses and highlighting the potential of combining type 1 and type 2 immunity.

30 Sep 2024

Study uncovers biological drivers of plasma proteins, offering new insights for disease biomarkers and drug discovery

Researchers mapped the biological influences on 4,775 plasma proteins, revealing the interplay of modifiable and non-modifiable factors, with key implications for disease biomarkers and drug targets.

30 Sep 2024

Not all ultra-processed foods are made alike: Researchers warn against villainizing entire food group

Researchers find that ultra-processed food (UPF) consumption may not be directly responsible for poor health outcomes, with lifestyle factors playing a significant role. More experimental research is needed to establish causality.

30 Sep 2024

How viral persistence and immune dysfunction drive long COVID

Study explores the biological drivers and mechanisms of long COVID, shedding light on its epidemiology and potential therapeutic interventions. It emphasizes the role of viral persistence, immune dysfunction, and coagulation in the development of this condition.

29 Sep 2024

Extending survival in meningioma patients with innovative radiopharmaceutical therapy

A radiopharmaceutical therapy that has successfully extended progression-free survival for patients with neuroendocrine tumors shows early promise for delivering similar benefits to patients with difficult-to-treat meningioma, a type of brain tumor.

29 Sep 2024

Medical Research News

Two genetic variants linked to Alzheimer's trigger microglial inflammation in females

New genetic syndrome bridges the gap between neurodevelopmental and neurodegenerative disorders

Falls linked to increased risk of dementia in older adults

Study explores whether certain brain proteins may play a role in Alzheimer's development

New insights into astrocytes offer hope for Alzheimer's treatment

Discovery of antibodies that boost complement activation against K. pneumoniae

Regulating iron overload: Liraglutide's potential benefits

Researchers uncover genetic link between bipolar disorder type I and epilepsy

Scientists discover potential new treatment for heart failure with preserved ejection fraction

Study links COVID-19 to increased risk of acute kidney disorders

Autoimmune diseases more common in women who stop ovulating before 40

Phytoene increases lifespan, reduces oxidative stress and amyloid toxicity

Over 80% of women are iron deficient by their third trimester

The consumption of flavonoid-rich foods was associated with a reduced risk of NAFLD among middle-aged adults

Owlstone Medical launches Breath Biopsy VOC Atlas® to unlock disease biomarkers in human breath

Researchers identify a protein that recharges T cells for long-lasting cancer remission

Study uncovers biological drivers of plasma proteins, offering new insights for disease biomarkers and drug discovery

Not all ultra-processed foods are made alike: Researchers warn against villainizing entire food group

How viral persistence and immune dysfunction drive long COVID

Extending survival in meningioma patients with innovative radiopharmaceutical therapy

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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