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Sleep deprivation disrupts brain regions that prevent unwanted memories

The link between poor sleep and mental health problems could be related to deficits in brain regions that keep unwanted thoughts out of mind, according to research from the University of East Anglia (UEA).

2 Jan 2025

Specialized bone marrow niches reveal secrets of immune tolerance

Researchers have uncovered a hierarchical structure of immune-privileged stem cells in bone marrow niches, revealing their regenerative potential and therapeutic relevance.

2 Jan 2025

Researchers develop tool to measure biological age in individual cell types

A new priority research paper, featured as the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 22, was published on December 29, 2024. The paper is titled "Cell-type specific epigenetic clocks to quantify biological age at cell-type resolution."

2 Jan 2025

MICAL2 enzyme found to promote tumor growth in pancreatic cancer

Pancreatic cancer kills 50,000 people each year, according to the National Cancer Institute, and there are few effective treatment options for the disease.

2 Jan 2025

Research reveals key to understanding kidney cancer treatment variability

Fighting cancer can seem like a deadly game of chance. While some patients may respond well to certain treatments, others might not be as fortunate.

2 Jan 2025

Histone markers predict human age with accuracy comparable to DNA methylation clocks

Researchers unveil histone-based age predictors, offering a new window into epigenetic aging and its shared patterns across tissues.

2 Jan 2025

Study reveals how fatty liver disease leads to liver cancer

Scientists at University of California San Diego School of Medicine have shed new light on the development of liver cancer, the sixth most frequently diagnosed cancer and fourth leading cause of cancer deaths worldwide.

2 Jan 2025

New research affirms clozapine safety with minimal blood cancer risk

An inter-departmental research team at the LKS Faculty of Medicine of the University of Hong Kong (HKUMed) has conducted the world's first analytic real-world cohort study on the association of clozapine, a highly efficacious antipsychotic drug, with the incidence of blood cancer.

2 Jan 2025

Physical activity linked to lower risk of having chronic conditions

University of Iowa researchers are recommending all patients be surveyed about their physical activity levels, after a new study underscores the link between physical activity and chronic disease.

2 Jan 2025

New insights into tristetraprolin's impact on basophil-mediated allergic inflammation

Inflammation is a crucial part of the body's defense mechanism, playing a key role in fighting infections and repairing tissue damage.

2 Jan 2025

New research reveals greater impact of Tobacco 21 policies

In 2020, the federal minimum age for buying tobacco products was officially raised from 18 to 21 as an increasing number of states and localities across the country sought to raise the age for tobacco purchases to protect the health of young adults.

2 Jan 2025

Yale study identifies molecular mechanism behind some lissencephaly disorders

Lissencephaly is a spectrum of rare, genetic disorders in which the brain fails to develop its hallmark folds.

2 Jan 2025

Research explores how carbon nanotubes help remove steroid hormones from water

Steroid hormones are among the most widespread aquatic micropollutants. They are harmful to human health, and they cause ecological imbalances in aquatic environments.

2 Jan 2025

Reframing gender gaps can spur action on female leadership

To many, Vice President Kamala Harris's loss in the 2024 presidential election was a sobering reminder of a larger and continuous gender gap across leadership positions in not only government, but also in business, higher education, and the military.

2 Jan 2025

AI models struggle in real-world medical conversations

Artificial intelligence tools such as ChatGPT have been touted for their promise to alleviate clinician workload by triaging patients, taking medical histories and even providing preliminary diagnoses.

2 Jan 2025

Discovery of nuclear speckles may improve cancer treatment decisions

Fighting cancer can seem like a deadly game of chance. While some patients may respond well to certain treatments, others might not be as fortunate. Doctors and scientists have long struggled to explain why.

2 Jan 2025

Psilocybin shows potential for treating mental health disorders in people with cancer and addiction

One or two doses of psilocybin, a compound found in psychedelic mushrooms, may improve the mental health of cancer patients when accompanied by psychotherapy, a new report suggests.

2 Jan 2025

New protein offers hope for heart regeneration

Researchers from the Bakkers group at the Hubrecht Institute have successfully repaired damaged mouse hearts using a protein from zebrafish.

2 Jan 2025

AI-driven surveillance system to combat emerging infectious diseases

Researchers have come up with a new way to identify more infectious variants of viruses or bacteria that start spreading in humans - including those causing flu, COVID, whooping cough and tuberculosis.

2 Jan 2025

Observational studies overestimate smoking's impact on CKD risk

A recent study published in Health Data Science led by Zhilong Zhang from the Institute of Medical Technology at Peking University Health Science Center and Professor Luxia Zhang from the National Institute of Health Data Science at Peking University has shed light on the complex relationship between smoking behavior and chronic kidney disease (CKD).

2 Jan 2025