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Study illuminates the origin and progression of bladder cancer

How bladder cancer originates and progresses has been illuminated as never before in a study led by researchers at Weill Cornell Medicine and the New York Genome Center.

9 Oct 2024

Study uncovers mechanism of MX protein in fighting HIV-1 and herpes simplex virus

A group of researchers led by Xavier Saelens and Sven Eyckerman at the VIB-UGent Center for Medical Biotechnology discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in these viruses and then trap them or even take them apart.

9 Oct 2024

First map of DNA modification in the hippocampus and prefrontal cortex created

A UCLA-led study has provided an unprecedented look at how gene regulation evolves during human brain development, showing how the 3D structure of chromatin - DNA and proteins - plays a critical role.

9 Oct 2024

Researchers discover potential therapeutic approach for triple negative breast cancer

Triple negative breast cancer (TNBC) remains the most aggressive and deadly type of breast cancer, but new findings from cancer researchers at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, are pointing the way toward therapeutic strategies that could be tested in clinical trials in the future.

9 Oct 2024

Dual immunotherapy plus chemotherapy shows promise for specific lung cancer patients

Researchers from The University of Texas MD Anderson Cancer Center have demonstrated that patients with metastatic non-squamous non-small cell lung cancer (NSCLC) harboring specific mutations in the STK11 and/or KEAP1 tumor suppressor genes were more likely to benefit from adding the immunotherapy tremelimumab to a combination of durvalumab plus chemotherapy to overcome treatment resistance typically seen in this patient population.

9 Oct 2024

New review explores Zika virus as a potential treatment for brain cancer

A new review was published in Oncotarget's Volume 15 on September 30, 2024, entitled, "Zika virus and brain cancer: Can Zika be an effective treatment for brain cancer? A systematic review."

9 Oct 2024

Researchers uncover neuronal mechanisms of human odor perception

We often only realize how important our sense of smell is when it is no longer there: food hardly tastes good, or we no longer react to dangers such as the smell of smoke.

9 Oct 2024

Novel antibody shows promise for pain relief in peripheral nerves

Cell surface proteins play a crucial role in cell communication and in sensing changes in the extracellular environment.

9 Oct 2024

Exploring the role of gut microbes in the aging process

Aging is a universal and complex process affecting all organisms, characterized by several genetic hallmarks such as telomere attrition, genomic instability, and epigenetic changes.

9 Oct 2024

Robotic buddy encourages toddlers to be more physically active

Parents seeking help in encouraging toddlers to be physically active may soon need to look no further than an inexpensive robotic buddy for their kids, a new study by Oregon State University suggests.

9 Oct 2024

Novel gene therapy holds potential in treating patients with epilepsy

Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) are working on a therapy that holds potential in treating patients with epilepsy, a neurological disorder defined by recurring seizures due to abnormal brain activity.

9 Oct 2024

Heavy alcohol consumption associated with increased risk of cardiac arrhythmias

Researchers at LMU University Hospital find cardiac arrhythmias in partygoers who had drunk a lot of alcohol.

9 Oct 2024

Vagus nerve stimulation enhances perceptual learning in mice

Just as a musician can train to more sharply distinguish subtle differences in pitch, mammals can improve their ability to interpret hearing, vision, and other senses with practice.

9 Oct 2024

Transposable elements found to be dysregulated in Alzheimer's brains, revealing potential targets for therapy

Study reveals widespread dysregulation of transposable elements (TEs) in aging human brains with Alzheimer's disease, using advanced techniques like CRISPR interference to identify TE-related risk genes.

9 Oct 2024

Groundbreaking study challenges treatment protocols for glioblastoma in older adults

A groundbreaking study led by Dr Monika E. Hegi, MD, PhD and European Organisation for Research and Treatment of Cancer (EORTC) headquarters team (Felix Oppong Msc, Dr Thierry Gorlia, PhD) reveals that older adults glioblastoma patients with truly unmethylated MGMT promoter do not benefit from temozolomide (TMZ) treatment, challenging current treatment protocols and paving the way for more personalised therapies.

9 Oct 2024

COVID-19 survivors at greater risk for heart attack, stroke and death

A history of COVID-19 can double the risk of heart attack, stroke or death according to new research led by Cleveland Clinic and the University of Southern California.

9 Oct 2024

Ultra-processed foods dominate children's diets from toddlerhood to middle childhood

Children's consumption of ultra-processed foods rises from toddlerhood to middle childhood, increasing intake of free sugars and sodium while reducing fiber intake. Early dietary patterns significantly influence long-term health outcomes.

9 Oct 2024

Gene therapy offers hope for children with cerebral adrenoleukodystrophy

Cerebral adrenoleukodystrophy (CALD) is a rare progressive, genetic brain disease that primarily presents in young boys, causing loss of neurological function and ultimately leading to early death.

9 Oct 2024

Impaired creatine metabolism identified in people with type 2 diabetes

A new study from Karolinska Institutet, published in Science Translational Medicine, shows that people with type 2 diabetes have lower levels of the protein that breaks down and converts creatine in the muscles.

9 Oct 2024

Smoking cessation programs could help combat opioid epidemic

Smoking is recognized as a leading cause of preventable disability and death. New research shows that as smokers increase their daily number of cigarettes, they report higher rates of chronic pain, more prescription opioid use, severe work limitations due to pain, and poor mental health.

9 Oct 2024