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Insights into clinical features and genetic variants of Cornelia de Lange syndrome in China

Cornelia de Lange syndrome (CdLS) is a rare genetic disorder with symptoms, including facial anomalies (such as fused eyebrows, short nose, upturned nose tip, and downturned mouth corners), growth retardation, small head (microcephaly), developmental delays, cognitive impairments, excess hair growth, and limb anomalies.

29 Aug 2025

Alzheimer’s research uncovers a new therapeutic pathway for the memory-robbing malady

The gut contains the largest collection of immune cells in the body. New research at the Buck Institute shows that some of those immune cells travel along the brain/gut axis in a mouse model of Alzheimer's disease (AD) providing a potential new therapeutic pathway for the memory-robbing malady.

29 Aug 2025

New off-the-shelf immunotherapy for metastatic kidney cancer could help improve outcomes

UCLA researchers have developed a new kind of immunotherapy that uses specially engineered immune cells equipped with built-in weapons to attack kidney cancer tumors and reprogram their protective environment - all without the need to customize treatment for each individual patient.

29 Aug 2025

Male and female bovine embryos show distinct development paths

Cornell researchers have uncovered the genetic triggers that cause male and female bovine embryos to develop differently, as early as seven to eight days after fertilization.

29 Aug 2025

Hormonal birth control influences emotion and memory in women

Hormonal birth control is a fact of life for millions of women. In the U.S. alone, more than 60 million women of reproductive age have used contraceptives according to the Centers for Disease Control and Prevention, most often to prevent pregnancy but also to manage conditions such as endometriosis, polycystic ovary syndrome and irregular cycles.

29 Aug 2025

Proteomic study reveals new drug targets in gastric signet ring cell carcinoma

Gastric signet ring cell carcinoma (GSRCC) is a distinct subtype of gastric cancer (GC) with unique epidemiological and pathogenic characteristics.

29 Aug 2025

Many preschoolers with ADHD receive medication before behavioral therapy

Young children with attention deficit/hyperactivity disorder often receive medication just after being diagnosed, which contravenes treatment guidelines endorsed by the American Academy of Pediatrics, a Stanford Medicine-led study has found.

29 Aug 2025

Inherited DNA changes can cause hormone imbalance in women with polycystic ovary syndrome

Increased testosterone levels are a consistent hormonal abnormality in women with polycystic ovary syndrome (PCOS). This study identified specific DNA variants in the gene DENND1A, which increase testosterone production in PCOS.

29 Aug 2025

Researchers identify genetic toolkit to reprogram cells into immune sentinels

An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialized immune cells.

29 Aug 2025

Disrupting protein quality control slows tumor growth in pediatric rhabdomyosarcoma

A new research paper was published in Volume 16 of Oncotarget on August 29, 2025, titled "In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma."

29 Aug 2025

Genetic clustering of swine influenza revealed in Northern Italy

A new scientific article, titled "Swine influenza surveillance in Italy uncovers regional and farm-based genetic clustering", has been published by Istituto Zooprofilattico Sperimentale delle Venezie as part of the Horizon Europe PAIR project.

29 Aug 2025

New study reveals how child neglect impacts critical brain pathways

When we think of child abuse, physical violence or emotional cruelty often comes to mind first. However, the most common form of maltreatment is actually much quieter: neglect.

29 Aug 2025

Metals and sulfate particles drive asthma hospitalizations linked to air pollution

Metals, particularly nickel and vanadium, and sulfate particles are the components of fine particulate air pollution (PM2.5) that most strongly contribute to the association between long-term exposure to air pollution and hospitalization among asthma sufferers, according to a new study led by Harvard T.H. Chan School of Public Health.

29 Aug 2025

Daily use of low-dose colchicine may slow growth of blood mutations linked to disease

Taking low-dose colchicine daily may slow the progression of a common acquired gene mutation found in the blood of older adults that can lead to certain blood cancers and increased risk of cardiovascular disease, according to a subanalysis of the LoDoCo2 trial published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at ESC Congress 2025.

29 Aug 2025

Glycosylation emerges as a key player in kidney disease progression

Kidney diseases affect nearly 700 million people worldwide and are a growing cause of mortality and health care costs.

29 Aug 2025

Predictable music phrases found to regulate blood pressure

A new study has found that blood pressure synchronises to predictable phrase structures in music. Blood pressure was more affected by loudness than tempo and was more strongly influenced by phrase structures that were more predictable.

29 Aug 2025

Herpes zoster vaccination linked to lower risk of heart attack and stroke

A new global systematic literature review and meta-analysis has shown that herpes zoster vaccination, used to prevent shingles, is associated with a statistically significant lower risk of heart attack and stroke.

29 Aug 2025

Clonogenic hepatocytes identified as engines of liver development

In a new study published in the Journal of Hepatology, researchers from the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) show that only 15–20% of hepatocytes in newborn mice - dubbed clonogenic hepatocytes - are responsible for generating over 90% of the adult liver mass.

29 Aug 2025

Sharp rise in pertussis hospitalizations highlights need for timely vaccination

Pertussis, commonly known as whooping cough, is a vaccine-preventable disease which continues to circulate even in areas where vaccination coverage is high, and outbreaks may still occur. A study published in Eurosurveillance and conducted at Meyer Children's Hospital in Florence, Italy, has found a sharp increase in hospitalisations for pertussis among children and adolescents (patients aged 16 years or under) in 2024.

29 Aug 2025

Adolescent anorexia linked to higher unemployment and lower earnings

Anorexia is a serious mental health disorder that typically begins during adolescence. A study, conducted by the Research Unit of Population Health and Oulu Business School at the University of Oulu, examined how anorexia in adolescence affects labor market position in adulthood compared with peers.

29 Aug 2025

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Medical Research News

Insights into clinical features and genetic variants of Cornelia de Lange syndrome in China

Alzheimer’s research uncovers a new therapeutic pathway for the memory-robbing malady

New off-the-shelf immunotherapy for metastatic kidney cancer could help improve outcomes

Male and female bovine embryos show distinct development paths

Hormonal birth control influences emotion and memory in women

Proteomic study reveals new drug targets in gastric signet ring cell carcinoma

Many preschoolers with ADHD receive medication before behavioral therapy

Inherited DNA changes can cause hormone imbalance in women with polycystic ovary syndrome

Researchers identify genetic toolkit to reprogram cells into immune sentinels

Disrupting protein quality control slows tumor growth in pediatric rhabdomyosarcoma

Genetic clustering of swine influenza revealed in Northern Italy

New study reveals how child neglect impacts critical brain pathways

Metals and sulfate particles drive asthma hospitalizations linked to air pollution

Daily use of low-dose colchicine may slow growth of blood mutations linked to disease

Glycosylation emerges as a key player in kidney disease progression

Predictable music phrases found to regulate blood pressure

Herpes zoster vaccination linked to lower risk of heart attack and stroke

Clonogenic hepatocytes identified as engines of liver development

Sharp rise in pertussis hospitalizations highlights need for timely vaccination

Adolescent anorexia linked to higher unemployment and lower earnings

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

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