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Clinically applicable strategy for early identification of IFN-AAB-positive COVID-19 patients

Researchers from the Humboldt-Universität zu Berlin have been investigating the presence of these antibodies in hospitalized COVID-19 patients to examine the potential of using them as a biomarker for severe disease.

17 Nov 2021

Excess mortality reveals infection speed in COVID-19 is low with seasonal infection patterns and escape variants

Researchers from the University of Wurzburg in Germany have been attempting to create a new method for determining the R0 using excess mortality data.

17 Nov 2021

SARS-CoV-2-related smell loss lasts longer than previously thought

A recent study discusses the long-term prevalence of olfactory dysfunction in COVID-19 patients.

17 Nov 2021

Game animals as potential drivers of disease emergence

A study characterized the total virome of game animals from five mammalian orders using the total RNA sequencing technique.

17 Nov 2021

Effect of contact networks on SARS-CoV-2 transmission and control

A study demonstrated that the social contacts created in different activity settings affect interventions needed to control outbreaks.

17 Nov 2021

Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

Researchers used advanced two-color fluorescence cross-correlation spectroscopy to demonstrate the interaction between human ACE2 and the S1 subunit of SARS-CoV-2 and SARS-CoV.

17 Nov 2021

Phantosmia, parosmia, and dysgeusia in COVID-19 patients

A team of researchers investigated qualitative aspects of olfactory and gustatory symptoms such as phantosmia, parosmia, and dysgeusia and their possible co-relation with the adaptive immune system.

17 Nov 2021

Efficacy of UVC light prototype devices for inactivating SARS-CoV-2

Researchers examined the efficacy of UVC light prototype devices to understand the duration and wavelength of UVC radiation needed for SARS-CoV-2 inactivation.

17 Nov 2021

SARS-CoV-2 protease suppresses host immune response by cleaving NEMO

A recent study conducted by a team of US-based scientists has highlighted a novel function of 3C-like protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The protease has been found to cleave a human immune signaling protein called NF-kB Essential Modulator (NEMO) and disrupt the host immune response.

16 Nov 2021

What genes affect the COVID-19 gender imbalance?

Many studies have established that coronavirus disease 2019 (COVID-19) is more infective in men than women, and men are more at risk of severe disease. While some have suggested that behavioral differences could explain increased transmission to men, this does not explain the more morbid prognosis.

16 Nov 2021

'Brain age' mostly relates to early life influences

Researchers in brain science and aging are very interested in measuring the health of a brain using a single observation. The most popular way to measure it is through a method called "brain age".

16 Nov 2021

New atomic-level insight of SARS-CoV-2 within a respiratory aerosol

In a paradigm-shifting paper currently available on the bioRxiv* preprint server, the researchers have dramatically extended the possibilities of computational microscopy in order to better understand both structure and dynamics of respiratory aerosols laden with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

16 Nov 2021

ALS also causes retinal alterations, study reveals

Amyotrophic lateral sclerosis (ALS), characterized by harm to brain neurons and to the spinal cord, also affects the tissue of the retina, according to a study headed up by Universidad Complutense de Madrid.

16 Nov 2021

New metabolic vulnerabilities of subsets of triple-negative breast cancer discovered

Researchers have identified a metabolic enzyme and pathway in some triple-negative breast cancer (TNBC) patients, which they hope could serve as a biomarker to select patients to receive targeted therapy.

16 Nov 2021

Scientists identify new gene that contributes to type 1 diabetes progression

When the pro-inflammatory pair, a receptor called CCR2 and its ligand CCL-2, get together, it increases the risk of developing type 1 diabetes, scientists report.

16 Nov 2021

New AI application reads eye movements

Eye movements read by a new AI application can reveal thoughts, memories, goals — and brain diseases.

16 Nov 2021

Unprecedented manufacturing strategy provides a template for equitable supply of vaccines

Today, as AstraZeneca reports 2 billion doses of the COVID-19 vaccine released for supply University of Oxford scientists explain how it has been possible to produce so much of the vaccine in less than a year, and the unprecedented strategy used to improve international equity of access.

16 Nov 2021

Study: Covid-19 vaccine-elicited immune cells persist six months after vaccination

A recent study by Johns Hopkins Medicine researchers provides evidence that CD4+ T lymphocytes — immune system cells also known as helper T cells — produced by people who received either of the two available messenger RNA (mRNA) vaccines for COVID-19 persist six months after vaccination at only slightly reduced levels from two weeks after vaccination and are at significantly higher levels than for those who are unvaccinated.

16 Nov 2021

Two genetic risk variants in Black individuals may exacerbate sepsis and COVID-19 severity

Two genetic risk variants that are carried by nearly 40 percent of Black individuals may exacerbate the severity of both sepsis and COVID-19, a team of researchers from the University of Pennsylvania's Perelman School of Medicine have found.

16 Nov 2021

A therapeutic interfering particle for SARS-CoV-2

Researchers report their attempt to engineer TIPs that can conditionally replicate with SARS-CoV-2, inhibit viral replication 10–100 fold, and exhibit R0>1.

16 Nov 2021