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New research has implications for developing cancer therapies targeting mutant p53 protein

The tumor suppressor protein p53 is mutated in more than half of all human cancers. Several drugs that potentially can restore mutant p53 to its normal cancer-killing function are in clinical investigation.

31 Aug 2021

Coronavirus buildup in the lungs is likely behind high mortality rates

A buildup of coronavirus in the lungs is likely behind the steep mortality rates seen in the pandemic, a new study finds.

31 Aug 2021

The tale of mRNA vaccines: Turning calamity into opportunity

In a review paper published in the journal Nature Reviews, researchers from Carnegie Mellon University and the University of Pennsylvania have described the underlying technologies for mRNA vaccines and their future prospects with improved delivery systems and applications in diseases beyond the ongoing COVID-19 pandemic.

31 Aug 2021

Researchers explore the fate of dietary fructose in the body

In today's fast-paced world, the dependence on the widely available "fast" foods and beverages has risen. These foods are typically low in fiber and essential nutrients, and often consist of high amounts of added sugar. This shift in dietary trends, accompanied by a sedentary lifestyle, has been attributed to the rise in various metabolic disorders like diabetes, fatty liver disease, and heart disease.

31 Aug 2021

Smart shirt made with carbon nanotube thread monitors the wearer’s heart rate

There's no need to don uncomfortable smartwatches or chest straps to monitor your heart if your comfy shirt can do a better job.

31 Aug 2021

Novel coating technology increases lifespan and stability of implantable devices

Various human implantable medical devices have been developed in recent years, and they are being used in clinical filed. These devices include brain–machine interfaces, in which a chip is implanted into the brain to enable humans to move machines using only their thoughts, and deep brain stimulators for treating Parkinson's disease and other brain diseases.

31 Aug 2021

SARS-CoV-2 animal origin: What we know so far

Scientists at the University of Glasgow Centre for Virus Research in the United Kingdom and the South China Agricultural University in Guangzhou, China, have shed light on the animal origin of SARS-CoV-2, tracing back to the first outbreak of the severe acute respiratory syndrome coronavirus (SARS-CoV), the infectious agent of the severe acute respiratory syndrome (SARS) in China in 2002 to 2003.

31 Aug 2021

University of Kentucky Center for Clinical and Translational Science receives $23.5 million NIH award

The University of Kentucky Center for Clinical and Translational Science has received a $23.5 million, four-year award from the National Center for Advancing Translational Sciences at the National Institutes of Health.

30 Aug 2021

COVID-19 vaccine elicits antibody responses in nearly 9 out of 10 people taking immunosuppressants

COVID-19 vaccination elicited antibody responses in nearly nine out of 10 people with weakened immune systems, although their responses were only about one-third as strong as those mounted by healthy people, according to a study by researchers at Washington University School of Medicine in St. Louis.

30 Aug 2021

Genetic tests can provide a better picture of cardiovascular disease risk than blood tests

Determining an individual's blood group based on genetic tests instead of merely traditional blood tests can provide a better picture of the risk of cardiovascular diseases.

30 Aug 2021

Computational study identifies human proteins structurally similar to SARS-CoV-2 proteins

A new study published in Scientific Reports identifies the human proteins that share structural similarities with the SARS-CoV-2 proteins.

30 Aug 2021

How early interferon curbs SARS-CoV-2 infection

A new study available in the Journal of Experimental Medicine focuses on the importance of interferon in SARS-CoV-2 infection.

30 Aug 2021

Researchers study the role of low-density granulocytes in COVID-19

Information on granulocytes helps to understand mechanisms associated with covid-19 and other infectious diseases. Such information also promotes the development of better diagnostic methods and therapies.

30 Aug 2021

Will mRNA vaccine boosters be required for SARS-CoV-2 variants?

A new study shows that the highly effective mRNA Moderna vaccine designed against the original SARS-CoV-2 strain may lose some efficacy as new variants arise.

30 Aug 2021

UH associate professor receives $2.5 million to explore how arterial hardening starts within cells

In diseases such as hypertension, aging, atherosclerosis, diabetes and chronic kidney disease, arterial calcification and stiffening of the elastic layer of the arterial wall are almost always present.

30 Aug 2021

Can SARS-CoV-2 be transmitted in the food cold chain?

A new study reports that the risk of transmitting SARS-CoV-2 through such fomites is very low.

30 Aug 2021

Development of extra protective broad-spectrum antimicrobial face shield

In a new study available on the preprint server Preprints*, researchers have innovated a transparent face shield with intrinsic antimicrobial activity.

30 Aug 2021

Daily walnut consumption lowers LDL cholesterol levels and may promote cardiovascular health

Eating about ½ cup of walnuts every day for two years modestly lowered levels of low-density lipoprotein (LDL) cholesterol, known as "bad cholesterol," and reduced the number of total LDL particles and small LDL particles in healthy, older adults, according to new research published today in the American Heart Association's flagship journal Circulation.

30 Aug 2021

Could genetic variants in host cell receptors (ACE2) explain COVID-19 susceptibility among certain ethnic groups?

Led by Ioannis Karakikes of Stanford University, a new study suggests some hospitalized patients with COVID-19 contain ACE2 genetic variants that increase ACE2 expression. Some variants that altered ACE2 protein expression and binding affinity were more prevalent in people with European backgrounds.

30 Aug 2021

Does SARS-CoV-2 natural infection immunity better protect against the Delta variant than vaccination?

A new study from Israel suggests immunity gained after recovering from a previous COVID-19 infection is more protective against the new Delta variant than vaccine-induced immunity. Natural immunity was estimated to be about 13 times stronger than having two doses of the Pfizer-BioNTech vaccine.

30 Aug 2021

Medical Science News

New research has implications for developing cancer therapies targeting mutant p53 protein

Coronavirus buildup in the lungs is likely behind high mortality rates

The tale of mRNA vaccines: Turning calamity into opportunity

Researchers explore the fate of dietary fructose in the body

Smart shirt made with carbon nanotube thread monitors the wearer’s heart rate

Novel coating technology increases lifespan and stability of implantable devices

SARS-CoV-2 animal origin: What we know so far

University of Kentucky Center for Clinical and Translational Science receives $23.5 million NIH award

COVID-19 vaccine elicits antibody responses in nearly 9 out of 10 people taking immunosuppressants

Genetic tests can provide a better picture of cardiovascular disease risk than blood tests

Computational study identifies human proteins structurally similar to SARS-CoV-2 proteins

How early interferon curbs SARS-CoV-2 infection

Researchers study the role of low-density granulocytes in COVID-19

Will mRNA vaccine boosters be required for SARS-CoV-2 variants?

UH associate professor receives $2.5 million to explore how arterial hardening starts within cells

Can SARS-CoV-2 be transmitted in the food cold chain?

Development of extra protective broad-spectrum antimicrobial face shield

Daily walnut consumption lowers LDL cholesterol levels and may promote cardiovascular health

Could genetic variants in host cell receptors (ACE2) explain COVID-19 susceptibility among certain ethnic groups?

Does SARS-CoV-2 natural infection immunity better protect against the Delta variant than vaccination?

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

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