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SARS-CoV-2 causes ER-stress-activated unfolded protein response leading to cell death

A new study describes the varying ways in which the virus co-opts the machinery of the host cell following infection to evade or modulate the host immune response, alter the pattern of translation of viral proteins, and the release of new viral particles.

24 Jun 2021

New tablet-sized device can profile multiple COVID-19 antibodies and biomarkers simultaneously

Biomedical engineers at Duke University in the USA have developed a device that detects coronavirus disease (COVID-19) antibodies as well as biomarkers that distinguish between antibodies produced in response to SARS-CoV-2 and four other coronaviruses with complete accuracy.

24 Jun 2021

New study suggests an earlier and faster spread of COVID-19 than initially thought

Researchers from Kent University in the UK have shown that the first coronavirus disease (COVID-19) patient likely dates back to October 2019. They also found that the spread to other continents of its causative pathogen – the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – occurred faster and sooner.

24 Jun 2021

Researchers discover a molecular pathway that triggers fatal cardiac atrophy

In many situations, heart muscle cells do not respond to external stresses in the same ways that skeletal muscle cells do. But under some conditions, heart and skeletal muscles can both waste away at fatally rapid rates, according to a new study led by experts at Cincinnati Children's.

24 Jun 2021

Long COVID has low prevalence in school-age children, UK study suggests

A new study, released as a preprint on the medRxiv* server, offers some insights into what may be expected in this field, how common it is, how it presents, and how it compares with chronic sequelae of other respiratory viruses.

24 Jun 2021

Hippocampal neurons fire during specific moments in time

Neurons in the hippocampus fire during specific moments in time, according to research recently published in JNeurosci. The cells may contribute to memory by encoding information about the time and order of events.

24 Jun 2021

New antibody conjugate delivers drugs to bone tumors and inhibits metastasis

Bone cancer is hard to treat and prone to metastasis. Research teams at Rice University and Baylor College of Medicine have a new strategy to attack it.

23 Jun 2021

Tips of cancer survivors' tongues are less sensitive to tastes, study finds

Most survivors of squamous cell head and neck cancers report that their sense of taste is dulled, changed or lost during radiation treatment, causing them to lose interest in eating and diminishing their quality of life.

23 Jun 2021

Western high-fat diet can increase the risk of chronic pain

A typical Western high-fat diet can increase the risk of painful disorders common in people with conditions such as diabetes or obesity, according to a groundbreaking paper authored by a team led by The University of Texas Health Science Center at San Antonio, also referred to as UT Health San Antonio.

23 Jun 2021

Flavoring can change how the brain responds to nicotine e-cigarettes

Flavoring can change how the brain responds to e-cigarette aerosols that contain nicotine, according to Penn State College of Medicine researchers.

23 Jun 2021

New coatings for titanium implants can fasten osseointegration

Researchers from Peter the Great St.Petersburg Polytechnic University (SPbPU) in collaboration with colleagues from St. Petersburg State University developed the coatings for titanium implants, which accelerate the implantation of the implant material into the bone tissue.

23 Jun 2021

Study focuses on retinal roughness in Alzheimer’s disease

Over recent years, the retina has established its position as one of the most promising biomarkers for the early diagnosis of Alzheimer's.

23 Jun 2021

Increased severity of COVID-19 in pregnancy

A new preprint on the medRxiv* server provides more evidence that COVID-19 likely causes a more serious phenotype to arise in pregnant women.

23 Jun 2021

Eating 2.5 grams of pure natural cocoa powder improves daytime visual acuity

Eating 2.5 grams of pure natural cocoa powder serves to improve visual acuity in healthy young adults and in daylight conditions, according to research by the Universidad Complutense de Madrid (UCM) and the ICTAN (Institute of Food and Nutrition Science and Technology) of the CSIC.

23 Jun 2021

Blood test shows promise for predicting treatment response in patients with advanced HPV-positive throat cancer

A sensitive blood test being developed by a team of researchers at the University of Michigan Rogel Cancer Center shows promise for predicting whether patients with metastatic HPV-positive throat cancer will respond to treatment months earlier than standard imaging scans.

23 Jun 2021

New method uses swabs from smartphone screens to accurately detect COVID-19

An accurate, non-invasive, and low-cost method of testing for COVID-19 using samples taken from the screens of mobile phones has been developed by a team led by UCL researchers at Diagnosis Biotech.

23 Jun 2021

Epstein-Barr virus reactivation may be the cause of long COVID symptoms

Epstein-Barr virus (EBV) reactivation resulting from the inflammatory response to coronavirus infection may be the cause of previously unexplained long COVID symptoms -- such as fatigue, brain fog, and rashes -- that occur in approximately 30% of patients after recovery from initial COVID-19 infection.

23 Jun 2021