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New therapeutic approach developed to treat psoriatic arthritis

An international team of researchers, led by UC Davis Health, has developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory disease affecting the joints.

3 Jun 2021

Antibody treatment reactivates the immune defense in patients with advanced-stage cancer

Researchers at the University of Turku, Finland, showed that the antibody treatment reactivates the immune defense in patients with advanced-stage cancer.

3 Jun 2021

Study explores COVID-19 vaccine beliefs and behaviors among college students

A recent study conducted by researchers at Pennsylvania State University in the US explored the beliefs and attitudes of students about vaccination in general and the COVID-19 vaccines in particular.

3 Jun 2021

How can nanomaterials help in the fight against COVID-19?

Researchers have reviewed different types of nanomaterials and how they can be used for the detection, prevention, and treatment of coronavirus disease 2019 (COVID-19).

3 Jun 2021

Researchers develop rapid antibody screening method for novel COVID-19 therapeutics development

New research undertaken by researchers in the USA describes two parallel but distinct in vivo approaches for the accelerated discovery of antibodies targeting SARS-CoV-2 spike protein.

3 Jun 2021

Known pharmaceutical compounds could provide new therapies for COVID-19

After screening over 12,000 existing treatments, researchers have found many promising antiviral compounds that could treat COVID-19.

3 Jun 2021

New nano-sized particles help improve detection of tumors within the body

Nano-sized particles have been engineered in a new way to improve detection of tumors within the body and in biopsy tissue, a research team in Sweden reports. The advance could enable identifying early stage tumors with lower doses of radiation.

3 Jun 2021

Cdkn1a transcript variant 2 is selectively elevated during natural aging across mouse tissues

Aging published "Cdkn1a transcript variant 2 is a marker of aging and cellular senescence" which reported that cellular senescence is a cell fate response characterized by a permanent cell cycle arrest driven primarily the by cell cycle inhibitor and tumor suppressor proteins p16Ink4a and p21Cip1/Waf1.

3 Jun 2021

New class of hydrogels can enable precise drug delivery

Hydrogels are commonly used inside the body to help in tissue regeneration and drug delivery. However, once inside, they can be challenging to control for optimal use. A team of researchers in the Department of Biomedical Engineering at Texas A&M University is developing a new way to manipulate the gel -- by using light.

3 Jun 2021

Researchers are closer to unraveling the mystery of science behind regeneration

Many salamanders can readily regenerate a lost limb, but adult mammals, including humans, cannot. Why this is the case is a scientific mystery that has fascinated observers of the natural world for thousands of years.

3 Jun 2021

Newly developed spheroidal structure reproduces the microenvironment of tumors

Every tumor is different, every patient is different. So how do we know which treatment will work best for the patient and eradicate the cancer? In order to offer a personalised treatment that best suits the case being treated, a team of scientists led by the University of Geneva (UNIGE), Switzerland, had already developed a spheroidal reproduction of tumors that integrates the tumor cells, but also their microenvironment.

3 Jun 2021

Single mutation to bat virus spike protein allows cell entry using human ACE2

In a paper recently uploaded to the preprint server bioRxiv by Kirchhoff et al. (May 31st, 2021) it is demonstrated that a single mutation to the RaTG13 spike protein results in significantly greater affinity towards the human receptor, indicating that the presence of a positively charged amino group at this position better facilitates interaction with the human ACE2 receptor, and helping to identify other viruses with zoonotic potential.

3 Jun 2021

European Virtual Institute receives award to explore brain circuits that underlie emotional behavior

A Marie Sklodowska-Curie Innovative Training Network will explore the brain circuits that underlie emotional behavior thanks to funding of 4.5 million euros by the European Research Council.

3 Jun 2021

New study will help design better antibodies for potential treatments

Scientists are harnessing hard X-rays in the fight against cancer. A team of researchers, in conjunction with the U.S. Department of Energy's (DOE) Argonne National Laboratory, has used ultrabright X-ray light to determine how specific types of antibodies can tell the difference between different forms of a cancer-linked molecule.

3 Jun 2021

People taking anti-inflammatory drug mount a weaker immune response to COVID-19 vaccine

One-quarter of people who take the drug methotrexate for common immune system disorders -- from rheumatoid arthritis to multiple sclerosis -- mount a weaker immune response to a COVID-19 vaccine, a new study shows.

2 Jun 2021

Long COVID patients at higher risk of small airway disease

The preprint discussed herein describes the effects of SARS-CoV-2 on lung structure and function in patients with long COVID.

2 Jun 2021

E484K mutation may confer immune evasion capability on UK variant of SARS-CoV-2

A new medRxiv* preprint reports the immunomodulatory effect of the E484K mutation newly acquired by the United Kingdom (U.K.) variant.

2 Jun 2021

Large-scale expansion of spike-reactive T cells feasible after COVID-19 vaccination

A new bioRxiv* preprint reports on the successful use of a protocol to expand SARS-CoV-2-reactive T-cells a thousand-fold.

2 Jun 2021

Study reveals how HIV prevents the maturation of myelin-making brain cells

It's long been known that people living with HIV experience a loss of white matter in their brains. As opposed to "gray matter," which is composed of the cell bodies of neurons, white matter is made up of a fatty substance called myelin that coats neurons, offering protection and helping them transmit signals quickly and efficiently.

2 Jun 2021

New insight into how platelets help resolve bacterial lung inflammation

Treating patients with acute respiratory failure is a constant challenge in intensive care medicine. In most cases, the underlying cause is lung inflammation triggered by a bacterial infection or - more rarely, despite being frequently observed at present due to the corona pandemic - a viral infection.

2 Jun 2021