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Researchers report long-lasting effects of gene therapy in children with deadly immune disorder

Over a decade ago, UCLA physician-scientists began using a pioneering gene therapy they developed to treat children born with a rare and deadly immune system disorder.

18 Oct 2021

Engineered 3D scaffolds of human brown adipose tissue as a new therapeutic strategy for obesity and diabetes

A group of researchers from various institutes in the USA addressed the limitations of BAT therapy by transplanting a low dose of brown adipocytes (BAs) without Matrigel to determine if this could alleviate high-fat diet-induced OB, metabolic symptoms, and T2DM in mice.

18 Oct 2021

Common treatment for MIS-C patients likely works by depleting neutrophils

Intravenous immune globulin (IVIG) — a common treatment for multisystem inflammatory syndrome in children (MIS-C) — likely works by depleting immune cells called neutrophils, according to a recent study funded by the National Institutes of Health.

15 Oct 2021

Metabolic restoration as a therapeutic approach to promote natural immune protection against HIV

The human immunodeficiency virus (HIV-1) particularly attacks CD4 lymphocytes, a type of white blood cell considered to be the conductor of the immune system.

15 Oct 2021

Researchers explore how opioids may have become so widely abused

Researchers may have uncovered new answers on how to create safer opioids. Design a new opioid to bypass the part of brain that feels pleasure, but retain the analgesic properties, which make opioids one of the most effective pain relievers.

15 Oct 2021

Phase 1 open-label trial shows SARS-CoV-2 DNA vaccine induces durable immune response

The efficacy and safety of a DNA-based vaccine are investigated, finding that the unique vaccine imparts a robust and long-lasting immunogenic response.

15 Oct 2021

The military as a disease vector and COVID-19

A recent systematic review aimed to study existing evidence for the military being a historically relevant disease vector that has been overlooked during the COVID-19 pandemic.

15 Oct 2021

Study finds menstrual bleeding changes after SARS-CoV-2 vaccination

A new study investigated menstrual bleeding patterns among current and former menstruating people, based on the premise that these bleeding changes were associated with changes in clotting or inflammation, which can affect the normal menstrual repair.

15 Oct 2021

Researchers develop new technique to improve understanding of how acid damages teeth

The University of Surrey and the School of Dentistry at the University of Birmingham have developed a new technique to improve understanding of how acid damages teeth at the microstructural level.

15 Oct 2021

Scientists identify gene responsible for food-dependent form of Cushing's Syndrome

A team of scientists in Montreal and Paris has succeeded in identifying the gene responsible for the development of a food-dependent form of Cushing's Syndrome, a rare disease affecting both adrenal glands.

15 Oct 2021

Salk researchers discover how the brain ignores distracting signals to coordinate movements

As you read this article, touch receptors in your skin are sensing your environment. Your clothes and jewelry, the chair you're sitting on, the computer keyboard or mobile device you're using, even your fingers as they brush one another unintentionally - each touch activates collections of nerve cells.

15 Oct 2021

Cell-based quadrivalent influenza vaccine produces sufficient immune response in children

A cell-based influenza vaccine has effectively provided protection against the flu in children and adolescents, according to a new study.

15 Oct 2021

Study unravels new mechanism for muscle repair after physiological damage

Muscle is known to regenerate through a complex process that involves several steps and relies on stem cells. Now, a new study led by researchers at Pompeu Fabra University (UPF, Spain)/Centro Nacional de Investigationes Cardiovasculares (CNIC, Spain)/CIBERNED (Spain) and Instituto de Medicina Molecular João Lobo Antunes (iMM, Portugal), published on 15 October in the journal Science, describes a new mechanism for muscle repair after physiological damage relying on the rearrangement of muscle fiber nuclei, and independently of muscle stem cells.

15 Oct 2021

RUDN study reveals macrophage dynamics in the regenerating liver after resection

RUDN University discovered the features of liver macrophages activation during its regeneration. In future, it can be used to develop new treatment methods for liver cirrhosis. The results are published in the Biomedicine.

15 Oct 2021

Moment-to-moment fluctuations in brain activity can reliably predict psychiatric treatment outcomes

It remains a central challenge in psychiatry to reliably judge whether a patient will respond to treatment.

14 Oct 2021

High intake of alpha linolenic acid associated with lower risk of mortality from all causes

A high intake of alpha linolenic acid (ALA) - found mainly in nuts, seeds, and plant oils - is associated with a lower risk of death from all causes, and specifically from diseases of the heart and blood vessels, finds a study published by The BMJ today.

14 Oct 2021

Post-trauma brain activity profiles may help predict long-term mental health outcomes

The way a person's brain responds to stress following a traumatic event, such as a car accident, may help to predict their long-term mental health outcomes, according to research supported by the National Institute of Mental Health, part of the National Institutes of Health.

14 Oct 2021

UC San Diego researchers receive NIH award to expand the study of developing brains

The National Institutes of Health has awarded researchers at University of California San Diego approximately $30 million over five years to expand and deepen longitudinal studies of the developing brain in children.

14 Oct 2021

Study reveals a detrimental role of the immune system in Lewy body dementias

T-cells respond to buildups of alpha-synuclein, the aggregated protein clumps that are a feature of neurodegenerative diseases including dementia with Lewy bodies and Parkinson's disease (PD), according to a Northwestern Medicine study published in Science.

14 Oct 2021

Aspirin use daily by healthy adults could be harmful

Scientists determine if the daily use of aspirin prolongs a healthy life span that is defined as being free from dementia and physical disability.

14 Oct 2021

Medical Science News

Researchers report long-lasting effects of gene therapy in children with deadly immune disorder

Engineered 3D scaffolds of human brown adipose tissue as a new therapeutic strategy for obesity and diabetes

Common treatment for MIS-C patients likely works by depleting neutrophils

Metabolic restoration as a therapeutic approach to promote natural immune protection against HIV

Researchers explore how opioids may have become so widely abused

Phase 1 open-label trial shows SARS-CoV-2 DNA vaccine induces durable immune response

The military as a disease vector and COVID-19

Study finds menstrual bleeding changes after SARS-CoV-2 vaccination

Researchers develop new technique to improve understanding of how acid damages teeth

Scientists identify gene responsible for food-dependent form of Cushing's Syndrome

Salk researchers discover how the brain ignores distracting signals to coordinate movements

Cell-based quadrivalent influenza vaccine produces sufficient immune response in children

Study unravels new mechanism for muscle repair after physiological damage

RUDN study reveals macrophage dynamics in the regenerating liver after resection

Moment-to-moment fluctuations in brain activity can reliably predict psychiatric treatment outcomes

High intake of alpha linolenic acid associated with lower risk of mortality from all causes

Post-trauma brain activity profiles may help predict long-term mental health outcomes

UC San Diego researchers receive NIH award to expand the study of developing brains

Study reveals a detrimental role of the immune system in Lewy body dementias

Aspirin use daily by healthy adults could be harmful

Advancing Motor Neuron Disease Diagnosis with Non-Invasive Ultrasound and AI

How agentic AI is reshaping laboratory workflows

Fourier 80: bringing benchtop NMR systems to the laboratory

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