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Novel ferritin nanoparticle vaccine candidate effective against SARS-CoV-2 variants in preclinical trials

A team of scientists from the United States has recently evaluated the efficacy of a ferritin nanoparticle-formulated, SARS-CoV-2 spike-based vaccine against newly emerged Variants of Concern (VOCs).

17 Jun 2021

Could type III interferons be used as a SARS-CoV-2 therapeutic?

Researchers have found that both type I and type III interferons can inhibit SARS-CoV-2 infection in human intestinal cells, but type III interferons can act faster and for a longer period, making them suitable for potential therapeutics.

17 Jun 2021

Could wastewater epidemiology help track the circulation of SARS-CoV-2 variants?

In a new study, released as a preprint on the medRxiv* server, researchers from Germany, Italy and Netherlands demonstrated the utility of integrating genomic and wastewater based epidemiology (WBE) to provide unprecedented insight into the abundance of SARS-CoV-2 and the profile of the mutations associated with the VOCs (i.e., B.1.1.7, B.1.351, P.1, and B.1.617.2) in the wastewater samples.

17 Jun 2021

Mouse-adapted SARS-CoV-2 and simian adenovirus vector advance COVID-19 vaccine research

A new preprint recently released on the bioRxiv* server describes the immunogenicity and protective potential of a novel adenovirus SARS-CoV-2 vaccine candidate against a form of the virus adapted to cause severe disease in mice. The findings show that this provides a useful mouse model for the study of new vaccines, in addition to demonstrating the protective efficacy of the current rhesus adenovirus vaccine candidate RhAd52.

17 Jun 2021

AI ECG as a novel noninvasive approach to diagnosing cardiac injury in COVID-19 patients

A recent study discusses the efficacy of an AI-enhanced ECG technique that has been used to diagnose left ventricular dysfunction in COVID-19 patients.

17 Jun 2021

What impacts public compliance with COVID-19 restrictions?

New research by scientists at Switzerland's Institute for Environmental Decisions reports that risk perception and public acceptance of NPIs depends on both worldview and levels of social trust. The study also found that, paradoxically, when the number of cases decreased in the period between the first and second waves, public willingness to comply with these measures fell.

17 Jun 2021

How the common cold can provide protection against COVID-19

In a recent study, researchers found that prior infection with the rhinovirus can provide a more effective immune response against SARS-CoV-2 infection.

17 Jun 2021

High junk food consumption in childhood increases risk of unhealthy body fat by early adulthood

A new paper published recently in the journal JAMA Pediatrics reports consistent and significant associations between the increased consumption of such ‘ultraprocessed foods’ by children in the UK, and a higher risk of obesity, increased body fat percentage, and overall body mass, by the time they reach young adulthood.

17 Jun 2021

A 'key clinical role' for community pharmacies in COVID-19 vaccination campaigns

Community pharmacies represent credible services across the UK, which could be key to COVID-19 vaccination campaigns.

17 Jun 2021

Landmark multiple myeloma study completes enrolment and method development

Binding Site is pleased to announce that the ground-breaking iStopMM study has reached an important milestone.

From Binding Site 17 Jun 2021

New noninvasive biomarker can be used in the diagnosis of NAFLD

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide and can progress to liver cirrhosis, liver failure or cancer. Currently, nonalcoholic steatohepatitis (NASH) diagnosis requires an invasive liver biopsy which can lead to procedural complications.

17 Jun 2021

MicroRNAs in urine could be a promising biomarker to diagnose brain tumors, study reveals

A recent study by Nagoya University researchers revealed that microRNAs in urine could be a promising biomarker to diagnose brain tumors.

17 Jun 2021

New technique shows promise as non-invasive intervention for congenital hearing loss

Broadband sounds embedded with short pauses can maintain temporal sound processing in a mouse model of hearing loss, according to new research published in eNeuro.

17 Jun 2021

New optic nerve stimulation protocol develops personalized visual signals to help the blind

Stimulation of the nervous system with neurotechnology has opened up new avenues for treating human disorders, such as prosthetic arms and legs that restore the sense of touch in amputees, prosthetic fingertips that provide detailed sensory feedback with varying touch resolution, and intraneural stimulation to help the blind by giving sensations of sight.

17 Jun 2021

New mouse model mimics human pathology of childhood restrictive cardiomyopathy

Severe childhood restrictive cardiomyopathy is a condition that causes the muscles in the walls of the heart to become stiff, so that the heart is unable to fill properly with blood.

17 Jun 2021

Using PET-CT scans to track the elimination of radiolabeled plastic particles in mice

Postdoctoral Researcher Outi Keinänen from the University of Helsinki developed a method to radiolabel plastic particles in order to observe their biodistribution on the basis of radioactivity with the help of positron emission tomography (PET).

17 Jun 2021

Immune cell-mimicking nanoparticles deliver drugs directly to inflamed lungs

Nanoengineers at the University of California San Diego have developed immune cell-mimicking nanoparticles that target inflammation in the lungs and deliver drugs directly where they're needed. As a proof of concept, the researchers filled the nanoparticles with the drug dexamethasone and administered them to mice with inflamed lung tissue.

17 Jun 2021

Importance of understanding different factors that causes ST segment abnormalities

In a new publication from Cardiovascular Innovations and Applications; Sharen Lee, Gary Tse, Xin Wang, Adrian Baranchuk and Tong Liu from Laboratory of Cardiovascular Physiology, Hong Kong, China, Second Hospital of Tianjin Medical University, Tianjin, China and Queen's University, Kingston, Ontario, Canada consider ST-segment depression in leads I and aVL.

16 Jun 2021

Bruisable artificial skin opens up opportunities for detecting damage in prosthetic devices

When someone bumps their elbow against a wall, they not only feel pain but also might experience bruising. Robots and prosthetic limbs don't have these warning signs, which could lead to further injury.

16 Jun 2021

UMSOM researchers receive $5 million federal grant to improve use of genetic risk scores

Researchers at the University of Maryland School of Medicine (UMSOM) have received a $5 million federal grant to pool genomic information from existing and new datasets - predominantly in African and African American populations -- in order to calculate the risk of developing specific diseases.

16 Jun 2021

Medical Science News

Novel ferritin nanoparticle vaccine candidate effective against SARS-CoV-2 variants in preclinical trials

Could type III interferons be used as a SARS-CoV-2 therapeutic?

Could wastewater epidemiology help track the circulation of SARS-CoV-2 variants?

Mouse-adapted SARS-CoV-2 and simian adenovirus vector advance COVID-19 vaccine research

AI ECG as a novel noninvasive approach to diagnosing cardiac injury in COVID-19 patients

What impacts public compliance with COVID-19 restrictions?

How the common cold can provide protection against COVID-19

High junk food consumption in childhood increases risk of unhealthy body fat by early adulthood

A 'key clinical role' for community pharmacies in COVID-19 vaccination campaigns

Landmark multiple myeloma study completes enrolment and method development

New noninvasive biomarker can be used in the diagnosis of NAFLD

MicroRNAs in urine could be a promising biomarker to diagnose brain tumors, study reveals

New technique shows promise as non-invasive intervention for congenital hearing loss

New optic nerve stimulation protocol develops personalized visual signals to help the blind

New mouse model mimics human pathology of childhood restrictive cardiomyopathy

Using PET-CT scans to track the elimination of radiolabeled plastic particles in mice

Immune cell-mimicking nanoparticles deliver drugs directly to inflamed lungs

Importance of understanding different factors that causes ST segment abnormalities

Bruisable artificial skin opens up opportunities for detecting damage in prosthetic devices

UMSOM researchers receive $5 million federal grant to improve use of genetic risk scores

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

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