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Study may offer an unexpected pathway for targeted treatment of brain tumors

In a new study led by Yale Cancer Center, researchers show the nucleoside transporter ENT2 may offer an unexpected path to circumventing the blood-brain barrier (BBB) and enabling targeted treatment of brain tumors with a cell-penetrating anti-DNA autoantibody.

15 Jun 2021

Research provides insights into why COVID-19 patients develop severe blood clots

Scientists have identified how and why some Covid-19 patients can develop life-threatening clots, which could lead to targeted therapies that prevent this from happening.

15 Jun 2021

Adapting COVID-19 vaccination strategies based on SARS-CoV-2’s evolution

Given the risk of SARS-CoV-2 developing new variants in unvaccinated individuals, vaccination sites are crucial. However, new research from the University of Michigan, USA, shows current vaccination programs may be worsening regional outbreaks when viral strains and SARS-CoV-2 escape mutations outdo vaccination rates.

15 Jun 2021

Could urine tests predict kidney injury and mortality in COVID-19?

A team of scientists from the Columbia University, New York, has recently identified a potential biomarker to predict acute kidney injury in COVID-19 patients. By analyzing urine samples of 444 COVID-19 patients, they have revealed that the urinary level of neutrophil gelatinase-associated lipocalin (NGAL) can be used to determine the severity and duration of acute kidney and tubular injuries, as well as to predict the risk of mortality in acute COVID-19 patients.

15 Jun 2021

RBD and NTD antibody cocktail could prevent the emergence of SARS-CoV-2 escape mutants

A new bioRxiv* preprint demonstrates how a combination of antibodies to two different regions on the viral spike could enhance neutralization efficiency as well as prevent the emergence of resistant variants.

15 Jun 2021

Does SARS-CoV-2 show seasonal variation in transmission in temperate countries?

The need to understand how and why such spread occurs is vital to containing it. A new medRxiv* preprint describes a significant reduction in transmission during the summer (by 42%), which is comparable to the impact of the most effective non-pharmaceutical intervention (NPI).

15 Jun 2021

Fusogenicity and resistance of SARS-CoV-2 B.1.1.7 and B.1.351 compared to D614G

A new study, released as a preprint on the bioRxiv* server, describes the biological effects induced by mutations in two circulating VOCs. These are the alpha and beta strains, also called B.1.1.7 and B.1.351, respectively.

15 Jun 2021

Potent antibodies against SARS-CoV-2 can be produced without T follicular helper cells, suggests study

It has been uncertain whether antibodies produced via this non-canonical pathway are protective against SARS-CoV-2. In a new study, recently released as a preprint on the bioRxiv*server, the neutralization potency of these antibodies is compared with those traditionally produced in germinal center-based antiviral responses.

15 Jun 2021

Researchers screen dual main protease-cathepsin L inhibitors against SARS-CoV-2

In a recent study released on the bioRxiv* preprint server, a selective dual inhibitor of MPRO and cathepsin L is described, producing synergistic results that suppress SARS-CoV-2 infection.

15 Jun 2021

Study finds ‘widespread’ use of toxic chemicals in a range of cosmetics

Cosmetics from the United States have been found to contain high levels of polyuoroalkyl substances (PFAS), associated with a range of harmful conditions.

15 Jun 2021

Carbon-based antimicrobial nanoweapons to fight COVID-19

In a recent review article published in the journal ACS Nano, interdisciplinary researchers from across the world evaluated the role of carbon-based nanomaterials (CBNs), such as fullerene, carbon dots, graphene, and their derivatives as promising alternatives to combat COVID-19 (coronavirus disease 2019) and other microbial infections.

15 Jun 2021

Study uncovers novel drug that effectively thwarts pancreatic tumors

Pancreatic cancer is an aggressive disease in which malignant cells form in the tissues of the pancreas, a long and flat gland located behind the stomach that helps with digestion and blood sugar regulation.

14 Jun 2021

High genetic running capacity promotes healthier metabolism in tissues as we age

High running capacity is associated with health and longevity. However, whether high genetic running capacity promotes more efficient metabolism with aging is not known.

14 Jun 2021

Stents inspired by kirigami could deliver drugs to tubular organs

Inspired by kirigami, the Japanese art of folding and cutting paper to create three-dimensional structures, MIT engineers and their collaborators have designed a new type of stent that could be used to deliver drugs to the gastrointestinal tract, respiratory tract, or other tubular organs in the body.

14 Jun 2021

New study pushes the memory clock back over a year

On average the earliest memories that people can recall point back to when they were just two-and-a-half years old, a new study suggests.

14 Jun 2021

Researchers demonstrate an alternative way to produce highly detailed images of the brain

The gold standard in functional brain imaging for over two decades, functional magnetic resonance imaging (fMRI) has transformed the landscape of research and clinical care. Yet, because of its cost and functional limitations, scientists have continued to look for new ways to see into the human brain.

14 Jun 2021

Medical Science News

Study may offer an unexpected pathway for targeted treatment of brain tumors

Research provides insights into why COVID-19 patients develop severe blood clots

Adapting COVID-19 vaccination strategies based on SARS-CoV-2’s evolution

Could urine tests predict kidney injury and mortality in COVID-19?

RBD and NTD antibody cocktail could prevent the emergence of SARS-CoV-2 escape mutants

Does SARS-CoV-2 show seasonal variation in transmission in temperate countries?

Fusogenicity and resistance of SARS-CoV-2 B.1.1.7 and B.1.351 compared to D614G

Potent antibodies against SARS-CoV-2 can be produced without T follicular helper cells, suggests study

Researchers screen dual main protease-cathepsin L inhibitors against SARS-CoV-2

Study finds ‘widespread’ use of toxic chemicals in a range of cosmetics

Carbon-based antimicrobial nanoweapons to fight COVID-19

Study uncovers novel drug that effectively thwarts pancreatic tumors

High genetic running capacity promotes healthier metabolism in tissues as we age

Stents inspired by kirigami could deliver drugs to tubular organs

New study pushes the memory clock back over a year

Researchers demonstrate an alternative way to produce highly detailed images of the brain

New approach to gene therapy uses common pain reliever to fight against genetic diseases

Artificial intelligence for predicting TMB-H colorectal cancer from histopathological characteristics

USC study suggests new treatment target for Alzheimer's disease in people with APOE4 gene

Nanoparticle-based therapy alleviates pulmonary hypertension in mouse model of rare lung disease

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

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