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Kirigami-inspired stent to improve drug delivery for diseases that affect tubular organs

Diseases that affect tubular structures in the body, such as the gastrointestinal (GI) system, vasculature and airway, present a unique challenge for delivering local treatments.

14 Jun 2021

Plant-based diet appears to offer protection against hypertension and preeclampsia

A plant-based diet appears to afford significant protection to rats bred to become hypertensive on a high-salt diet, scientists report. When the rats become pregnant, the whole grain diet also protects the mothers and their offspring from deadly preeclampsia.

14 Jun 2021

Researchers examine the importance of time after COVID-19 vaccination

A new study has been published on the medRxiv* preprint server, which deals with the importance of time post-vaccination based on the quantification of VOC immune evasion. The current study developed a toy model to estimate the effectiveness of the vaccines against VOC over time. Researchers have shown that the estimated value is highly dependent on time post-vaccination. Additionally, this model can describe the implications of changes in vaccine efficacy against VOC.

14 Jun 2021

LSU Health New Orleans receives $2.38 million in funding to sequence SARS-CoV-2 variants

LSU Health New Orleans has been awarded $2.38 million in funding to lead partnerships to sequence SARS-CoV-2 variants.

14 Jun 2021

Robust immunity against SARS-CoV-2 with Pfizer vaccine is mediated by memory B cells

A reassuring study, released as a preprint on the medRxiv* server, from a multi-institutional team of researchers in Italy suggests that with the Pfizer-BioNTech BNT162b2 vaccine, post-vaccination immunity against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is both robust and durable.

14 Jun 2021

Intranasal monoclonal SARS-CoV-2 antibody therapy shows promise in preclinical trials

A new study, released as a preprint on the bioRxiv* server, presents a new monoclonal antibody (MAb) called DZIF-10c that powerfully neutralizes SARS-CoV-2, including the current variants of concern (VOCs). With high bioavailability in the lungs and wide distribution in the body, the antibody was able to prevent SARS-CoV-2 infection in mice after intranasal administration.

14 Jun 2021

Bone density scan can detect calcium build-up linked to higher risk of serious falls

The build-up of calcium in a major blood vessel is linked with a 39 per cent higher risk of serious falls in older women, new Edith Cowan University (ECU) research has found.

14 Jun 2021

Fatty acid binding site on SARS-CoV-2 spike triggers spike monomer crosstalk that is key to infectivity

A new study, released as a preprint on the bioRxiv* server, examines the role played by a fatty acid called linoleic acid (LA) that attaches at a binding site near the receptor-binding domain (RBD) of the spike protein. The spike exists as a homotrimer in open or closed conformations. In the former, at least one RBD points upwards.

14 Jun 2021

Can rapid antigen tests help screen for COVID-19?

The spread of SARS-CoV-2 is driven by the high proportion of asymptomatic and very mild infections, allowing people to move around and engage in public activity normally. There are many modeling studies that suggest that large-scale screening for the presence of this virus can help curb transmission at this point, from people with few or no symptoms. A new study points out the accuracy of SARS-CoV-2 antigen-detection rapid diagnostic tests for this purpose when used at the point-of-care.

14 Jun 2021

COVID-19 in pregnancy could be less severe than previously thought: A Danish case study

A reassuring study by researchers in Denmark indicates that while 5% of pregnant women with COVID-19 may require hospitalization, severe maternal and neonatal outcomes are rare.

14 Jun 2021

Delays and shortages hit SARS-CoV-2 genomic surveillance program

A new study from the Institute of Bioinformatics and Applied Biotechnology (IBAB), Bengaluru, India, provides an overview of how well this important monitoring mechanism is functioning around the world. The team has released their findings as a preprint on the bioRxiv* server.

14 Jun 2021

Emerging SARS-CoV-2 variants contain mutations that interfere with genomic sequencing

A recent study by researchers in Canada shows how mutations in newly emerging lineages of SARS-CoV-2 may disrupt the sequencing process and thus interfere with this important area of research.

14 Jun 2021

Simpleware ScanIP Medical Receives FDA 510(k) Clearance for 3D Medical Printing

Synopsys’ Simpleware ScanIP Medical is now available for 3D medical printing after receiving FDA 510(k) clearance in this area.

From Synopsys Simpleware™ Software 14 Jun 2021

Study reports self-disinfecting polymer surfaces that can inactivate SARS-CoV-2

Surfaces with anionic block copolymers can inactivate different viruses within minutes by making the polymer-microbe interface very acidic. Such surfaces can continuously disinfect surfaces without the need for reapplication of disinfectant.

14 Jun 2021

Study suggests COVID-19 in children is milder than the flu

Researchers retrospectively analyzed the medical records of children in Turkey hospitalized because of coronavirus disease 2019 (COVID-19) or influenza and found COVID-19 to be milder than influenza in this group.

14 Jun 2021

Super-resolution imaging technique could enable early detection of neurological disorders

A new imaging technique has the potential to detect neurological disorders--such as Alzheimer's disease--at their earliest stages, enabling physicians to diagnose and treat patients more quickly.

13 Jun 2021

Role of traditional medicine against SARS-CoV-2

A group of researchers at Kannur University reviewed selected papers and in silico work on potential drug leads that could be used to manage COVID-19.

13 Jun 2021

Study shows poor antibody response in naive elderly of nursing homes after mRNA vaccination

A new study describes inadequate antibody responses to the Pfizer/BioNTech vaccine against coronavirus disease 2019 (COVID-19) in elderly residents of a care home with no prior history of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), compared to those with such a history. This adds to the current understanding of vaccine efficacy against infection.

13 Jun 2021

Calcified Tissue International announces top 10 most impactful papers of 2019

Calcified Tissue International and Musculoskeletal Research is among the leading peer-reviewed journals publishing original preclinical, translational, and clinical research as well as expert reviews in the bone and musculoskeletal field.

13 Jun 2021

New radiopharmaceutical shows therapeutic efficacy in preclinical model of ovarian cancer

Preclinical trials of a new radiopharmaceutical to treat ovarian cancer have produced successful results, dramatically limiting tumor growth and decreasing tumor mass.

11 Jun 2021

Medical Science News

Kirigami-inspired stent to improve drug delivery for diseases that affect tubular organs

Plant-based diet appears to offer protection against hypertension and preeclampsia

Researchers examine the importance of time after COVID-19 vaccination

LSU Health New Orleans receives $2.38 million in funding to sequence SARS-CoV-2 variants

Robust immunity against SARS-CoV-2 with Pfizer vaccine is mediated by memory B cells

Intranasal monoclonal SARS-CoV-2 antibody therapy shows promise in preclinical trials

Bone density scan can detect calcium build-up linked to higher risk of serious falls

Fatty acid binding site on SARS-CoV-2 spike triggers spike monomer crosstalk that is key to infectivity

Can rapid antigen tests help screen for COVID-19?

COVID-19 in pregnancy could be less severe than previously thought: A Danish case study

Delays and shortages hit SARS-CoV-2 genomic surveillance program

Emerging SARS-CoV-2 variants contain mutations that interfere with genomic sequencing

Simpleware ScanIP Medical Receives FDA 510(k) Clearance for 3D Medical Printing

Study reports self-disinfecting polymer surfaces that can inactivate SARS-CoV-2

Study suggests COVID-19 in children is milder than the flu

Super-resolution imaging technique could enable early detection of neurological disorders

Role of traditional medicine against SARS-CoV-2

Study shows poor antibody response in naive elderly of nursing homes after mRNA vaccination

Calcified Tissue International announces top 10 most impactful papers of 2019

New radiopharmaceutical shows therapeutic efficacy in preclinical model of ovarian cancer

A new method to measure intracellular water in biological systems

Obesity, GLP-1s, and metabolic care

Automation in cell-based workflows

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