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New protein target offers promise for alleviating cognitive decline in Parkinson's disease

A recently published study by researchers at the University of Arizona Health Sciences found that a tiny protein called PNA5 appears to have a protective effect on brain cells, which could lead to treatments for the cognitive symptoms of Parkinson's disease and related disorders.

19 Nov 2024

Study investigates impact of oxygen therapy on oxidative stress in patients with COVID-19 pneumonia

Severe COVID-19 pneumonia often requires high concentrations of oxygen, which can potentially lead to oxidative stress and lung injury.

19 Nov 2024

New research links sphingolipids to heart disease and atherosclerosis

Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns.

19 Nov 2024

Study provides insight into how low-dose ketamine alleviates symptoms of major depression

University at Buffalo neuroscientists have identified the binding site of low-dose ketamine, providing critical insight into how the medication, often described as a wonder drug, alleviates symptoms of major depression in as little as a few hours with effects lasting for several days.

19 Nov 2024

Research uncovers how inhaled house dust mites trigger of allergic asthma

New research from the University of Pittsburgh uncovers how inhaled house dust mites, a common trigger of allergic asthma, activate the immune system and drive this disease in mice.

19 Nov 2024

Study reveals variability in polygenic risk scores for predicting heart disease

Polygenic risk scores (PRSs) are a cutting-edge tool in genetics, combining information from genetic markers across the genome to estimate a person's risk of developing certain diseases, such as coronary artery disease (CAD).

19 Nov 2024

New CAR T-cell therapy shows promise against aggressive HER2+ breast cancer

One-third of HER2-positive (HER2+) tumors express the P95HER2 protein, which associates with an aggressive form of breast cancer with a poorer prognosis. Investigators of the Vall d'Hebron Institute of Oncology's (VHIO) Growth Factors Group, in collaboration with researchers of the Cancer Research Program of Hospital del Mar Research Institute (HMRI), Barcelona, have developed novel chimeric antigen receptor (CAR) T-cell therapy that can produce a potent antitumor response against p95HER2-expressing cells.

19 Nov 2024

Malaria crystal structure offers clues for more effective medications

Prof. Leslie Leiserowitz first became intrigued by malaria when he was a young boy in South Africa. His father, who scouted the continent in search of wood for the family business, brought back not only tales of elephants and gorillas but also skin rashes and ringing in his ears, side effects of the quinine he took to prevent malaria.

19 Nov 2024

Peptide hydrogel boosts antibiotic effectiveness against resistant bacteria

Research from Chalmers University of Technology, Sweden, shows that resistant bacteria can regain susceptibility to antibiotics when the treatment is combined with a material equipped with antibacterial peptides.

19 Nov 2024

Study reveals the power of sleep in enhancing motor learning for individuals with brain injury

New research published by scientists at Kessler Foundation provides critical insights into the role of sleep in motor learning for individuals recovering from traumatic brain injury (TBI).

19 Nov 2024

Athletes show better working memory performance than non-athletes

In cognitive science, there has recently been increasing attention to the relationship between sports expertise and working memory.

19 Nov 2024

New cell model reveals how hepatitis E viruses affect nerve cells

Using a new cell model, researchers can for the first time study how hepatitis E viruses affect nerve cells.

19 Nov 2024

MSU researchers develop method for earlier disease detection using blood proteins

Medical professionals have long known that the earlier a disease is detected, the higher the chance for a better patient outcome.

19 Nov 2024

New nasal vaccine could help stop the spread of whooping cough

As whooping cough cases rise in the U.S., a new nasal vaccine developed by Tulane University may hold the key to reducing the spread of the highly contagious respiratory disease.

19 Nov 2024

Stress, diet, and vascular health: Can cocoa flavonols help?

Incorporating flavonol-rich foods may counteract stress-induced vascular impairments, offering a dietary strategy for improved cardiovascular health.

19 Nov 2024

UQ swimming program reverses motor decline in young people with severe cerebral palsy

A competitive swimming program developed by University of Queensland researchers for young people with severe cerebral palsy has reversed motor decline associated with the condition.

19 Nov 2024

Impact of glucagon-like peptide-1 receptor agonists on alcohol consumption

The impact of GLP-1 RAs on alcohol use is explored, showing potential benefits in reducing intake and cravings, but with mixed results from clinical trials.

19 Nov 2024

Chewing gum to prevent preterm birth

Xylitol-containing gum during pregnancy significantly reduces preterm births and low birth weights, offering a simple solution for improving maternal health.

19 Nov 2024

By 2050, two-thirds of adults and one-third of adolescents could face obesity in the US

Rising obesity rates in the USA, particularly among adolescents, pose significant health risks, demanding immediate action and tailored prevention strategies.

19 Nov 2024

Memories of obesity can linger in fat cells long after weight loss

Epigenetic changes from obesity persist after weight loss, altering fat cell function and increasing the risk of weight regain, impacting metabolic health.

19 Nov 2024