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Study reveals route of entry for Semliki Forest virus into the brain

In a recent study, researchers from Uppsala University show that the Semliki Forest virus enters the central nervous system by first entering the cerebrospinal fluid and then binding to a specific cell type before penetrating deeper into the brain.

13 Jan 2025

CeVD-related brain network phenotype can provide insights into cognitive decline trajectory

Researchers have uncovered novel insights into how brain function disruptions related to cerebrovascular disease (CeVD) interact with Alzheimer's disease (AD) pathology to impact neurodegeneration and cognition in older adults.

13 Jan 2025

NFL players prescribed very few opioids for pain management

Due to the physical contact nature of their occupation, the elite athletes of the National Football League (NFL) often experience pain.

13 Jan 2025

Inflammasome protects stem cells from becoming cancerous

A group of immune proteins called the inflammasome can help prevent blood stem cells from becoming malignant by removing certain receptors from their surfaces and blocking cancer gene activity, according to a preclinical study by Weill Cornell Medicine investigators.

13 Jan 2025

Study reveals how Zika virus hijacks host protein for reproduction

The mosquito-borne Zika virus is known for causing microcephaly, a birth defect in which abnormal brain development results in a smaller-than-expected head.

13 Jan 2025

ORACLE test enhances prediction of lung cancer outcomes

A new test, developed by researchers from UCL Cancer Institute and the Francis Crick Institute, can better predict lung cancer survival at the point of diagnosis, which could inform treatment decisions and potentially reduce the risk of the cancer returning or spreading.

13 Jan 2025

The impact of extreme weather events on HIV prevention and care

Researchers review the impact of extreme weather events related to climate change on HIV strategies.

13 Jan 2025

Women experience higher waiting-list mortality in lung transplantation

Research highlights gender-based disparities in lung transplantation, showing women face longer wait times yet achieve better post-transplant survival outcomes.

13 Jan 2025

New test could predict lung cancer outcomes using tumor DNA

Scientists from the Francis Crick Institute, UCL, UCLH and Personalis have found that a test to detect circulating tumor DNA can predict lung cancer outcome in a Cancer Research UK-funded study.

13 Jan 2025

Discovery of key protein for burning fat may lead to obesity treatments

Obesity, which affects 650 million people worldwide, influences the development of cardiometabolic diseases and increases the risk of cancer.

13 Jan 2025

By 2060, 1 million U.S. adults are projected to develop dementia annually

The lifetime risk of dementia is 42%, with significant variations by race and sex, underscoring the importance of public health strategies for prevention.

13 Jan 2025

Short-chain fatty acids propionate and butyrate directly modify chromatin to regulate gene expression

Short-chain fatty acids influence gene regulation and chromatin accessibility, highlighting their role in colorectal cancer and normal cellular processes.

13 Jan 2025

Sleep loss triggers intrusive memories by disrupting REM sleep

Sleep deprivation affects the brain's memory control, with REM sleep essential for effective suppression of intrusive memories and cognitive function.

13 Jan 2025

Study finds certain H5N1 strains in cattle linked to milder human illness; other variants remain a concern

Study reveals that contemporary HPAI H5N1 viruses show reduced replication and immune activation in human lung organoids, potentially explaining milder disease in humans compared to historic strains.

13 Jan 2025

Mortality risks soar with ultra-processed foods - simple diet changes can help

Ultra-processed food consumption increases mortality risks, particularly from circulatory, digestive diseases, and Parkinson's, but substituting minimally processed foods can lower these risks.

12 Jan 2025

Being fit matters more than weight for long-term health, research shows

Cardiorespiratory fitness significantly reduces mortality risks regardless of BMI, highlighting fitness as a critical health determinant over weight loss strategies.

12 Jan 2025

Totally implantable cochlear implant promises a new era of hearing restoration

Scientists have developed a totally implantable cochlear implant that delivers hearing performance comparable to conventional devices while improving quality of life and eliminating the need for external components.

12 Jan 2025

Plant chemical discovered to prevent biofilm formation

If your teeth have ever felt fuzzy after skipping a brushing, you've encountered biofilm-a slimy bacterial layer that clings to surfaces. In medical settings, biofilms make infections harder to treat when they form protective shields for bacteria on devices like catheters and implants.

10 Jan 2025

New guidelines for correct use of biochemical indices of bone statuss published

The Joint International Osteoporosis Foundation (IOF) Working Group and the International Federation of Clinical Chemistry (IFCC) Committee on Bone Metabolism have published important updated guidelines for the correct use of biochemical indices of bone status.

10 Jan 2025