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How neural and hormonal gut-brain communication shapes metabolism and health

Interoception research reveals how gut-brain communication via neural, hormonal, and microbial pathways regulates metabolism, hunger, and overall health, offering insights for therapeutic innovations.

25 Nov 2024

New discovery reveals dual binding in bitter taste receptors

"Tasting Upside-Down - An Unusual Sensing Mechanism was Found in Human Bitter Sensing" A new study revealed that some bitter molecules target their sensor through binding simultaneously at two distinct locations, one outside the cell, and the other inside it.

25 Nov 2024

Study links mother's emotional speech to infant oxytocin levels

Infants whose mothers regularly use language to describe what their child is thinking or feeling, have higher levels of the hormone oxytocin, finds a new study led by UCL researchers.

25 Nov 2024

New brain biomarker could enable early diagnosis of psychosis

The current standard of care for psychosis is a diagnostic interview, but what if it could be diagnosed before the first symptom emerged? Researchers at the Del Monte Institute for Neuroscience at the University of Rochester are pointing toward a potential biomarker in the brain that could lead to more timely interventions and personalized care.

25 Nov 2024

Dopamine and serotonin balance reward learning in opposing ways

If you've heard of two of the brain's chemical neurotransmitters, it's probably dopamine and serotonin. Never mind that glutamate and GABA do most of the work - it's the thrill of dopamine as the "pleasure chemical" and serotonin as tender mood-stabilizer that attract all the headlines.

25 Nov 2024

New discovery in the peripheral nervous system could help control obesity

An international team of researchers has discovered a new component of the peripheral nervous system that acts by increasing energy metabolism in the body.

25 Nov 2024

Researchers identify brain circuit behind sexual rejection in females

A team from the Champalimaud Foundation (CF) has pinpointed a critical neural circuit for sexual rejection, identifying a set of brain cells that play a crucial role in determining whether a female accepts or rejects mating attempts based on her reproductive cycle.

25 Nov 2024

U.S. restaurants face scrutiny over antibiotic policies

U.S. restaurant chains face scrutiny for their role in antibiotic resistance, with Chipotle leading the way and others lagging behind in transparency and policy implementation.

25 Nov 2024

Brain volume loss linked to Alzheimer's treatment may be caused by amyloid plaque removal

A loss of brain volume associated with new immunotherapies for Alzheimer's disease may be caused by the removal of amyloid plaques, rather than the loss of neurons or brain tissue, finds a study led by UCL researchers.

25 Nov 2024

IASLC and LCRF announce first grant recipient for lung cancer research

The International Association for the Study of Lung Cancer (IASLC) and The Lung Cancer Research Foundation (LCRF) announce the first grant recipient of the IASLC LCRF Team Science Research Grant on the Next Step in the Cure of Oncogene-Driven Lung Cancers Award.

25 Nov 2024

ASTRO releases updated guidelines for treating locally advanced rectal cancer

The American Society for Radiation Oncology (ASTRO) issued today an updated clinical guideline for physicians who use radiation therapy to treat patients with locally advanced rectal cancer.

25 Nov 2024

History of endometriosis and fibroids linked to higher long-term risk of early death

Researchers examine the impact of endometriosis and uterine fibroids on the risk of early death.

25 Nov 2024

How breast cancer patients respond to tamoxifen may be linked to the gut microbiome

A new study has shown that variation in the microbiota of the human gut impacts the pharmacokinetics of tamoxifen and thus the effectiveness of the drug.

25 Nov 2024

Physical activity essential at all stages of adult life

The research reveals that physical activity is key to lowering mortality risk, with stronger effects in older adults compared to other health factors over time.

25 Nov 2024

Study reveals the secret to cellular youth may lie in nucleolus size

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators.

25 Nov 2024

Research identifies the brain's 'locus coeruleus' as key player in sleep cycles

Researchers at the University of Lausanne have identified a novel role for the brain's 'locus coeruleus' in sleep and its disruptions.

25 Nov 2024

Researchers develop new approach to effectively deliver therapeutics into the brain

Researchers at the Icahn School of Medicine at Mount Sinai have developed an innovative approach - demonstrated in mouse models and isolated human brain tissue - to safely and effectively deliver therapeutics into the brain, providing new possibilities for treating a wide range of neurological and psychiatric diseases.

25 Nov 2024