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Targeting intracellular checkpoints to enhance NK cell immunotherapy

Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.

27 Nov 2024

Strategic participant selection boosts reliability in brain imaging studies

Brain-wide association studies, which use magnetic resonance imaging to identify relationships between brain structure or function and human behavior or health, have faced criticism for producing results that often cannot be replicated by other researchers.

27 Nov 2024

Novel mRNA-based therapy offers hope for patients with proliferative vitreoretinopathy

A new preclinical study by Mass Eye and Ear investigators showed that a novel mRNA-based therapy may be able to prevent blindness and scarring from proliferative vitreoretinopathy (PVR) following a retinal detachment repair or traumatic injury to the eye.

27 Nov 2024

Stanford team uses natural cell death mechanism to kill cancer cells

Our bodies divest themselves of 60 billion cells every day through a natural process of cell culling and turnover called apoptosis.

27 Nov 2024

DNA-based nanorobotic hand could block viruses and enable rapid diagnostics

A tiny, four-fingered "hand" folded from a single piece of DNA can pick up the virus that causes COVID-19 for highly sensitive rapid detection and can even block viral particles from entering cells to infect them, University of Illinois Urbana-Champaign researchers report.

27 Nov 2024

Study reveals protein mobility defect as a key factor in chronic diseases

Chronic diseases like type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of disease burden and deaths around the globe, are physically and economically taxing, and the number of people with such diseases is growing.

27 Nov 2024

TRiC mutations found to cause developmental brain malformations in children

In 1992, Judith Frydman, PhD, discovered a molecular complex with an essential purpose in all of our cells: folding proteins correctly.

27 Nov 2024

Fungus found in the mouse stomach may hold a key to fungal evolution in the gut

A fungus discovered in the mouse stomach may hold a key to fungal evolution within the gastrointestinal tract, according to new research led by Weill Cornell Medicine investigators.

27 Nov 2024

Philadelphia beverage tax: Did it curb childhood obesity?

The 2017 Philadelphia beverage tax aimed to reduce sugar-sweetened beverage consumption and improve pediatric health. While it significantly reduced sugary drink purchases, its impact on overall pediatric weight was limited, with minor changes observed in specific subgroups.

27 Nov 2024

Research challenges old ideas on the evolution of brain size

Modern humans, Neanderthals, and other recent relatives on our human family tree evolved bigger brains much more rapidly than earlier species, a new study of human brain evolution has found.

27 Nov 2024

New insights into cationic polymer structure in RNA drug delivery

LMU researchers have investigated how cationic polymers organize on a molecular level when transporting RNA drugs.

27 Nov 2024

Steep decline in cervical cancer deaths among young women in US

Research shows a dramatic 62% decrease in cervical cancer mortality in U.S. women under 25, attributed to HPV vaccination and enhanced screening efforts.

27 Nov 2024

New gold-based drug proves to be more potent than standard chemotherapy

A new gold-based drug can slow tumour growth in animals by 82% and target cancers more selectively than standard chemotherapy drugs, according to a study by Australian and Indian researchers.

27 Nov 2024

GLP-1 receptor agonists reduce kidney failure risk and cardiovascular events

Researchers evaluate the effects of glucagon-like peptide-1 receptor agonists on kidney and cardiovascular outcomes.

27 Nov 2024

Depression increases chances of experiencing menstrual pain

Scientists investigate the genetic relationship between depression and dysmenorrhea.

27 Nov 2024

AI models beat human experts in forecasting neuroscience study results

Large language models, a type of AI that analyses text, can predict the results of proposed neuroscience studies more accurately than human experts, finds a new study led by UCL (University College London) researchers.

27 Nov 2024

Soccer heading may cause long-term brain damage

Soccer heading may cause more damage to the brain than previously thought, according to a study being presented next week at the annual meeting of the Radiological Society of North America (RSNA).

27 Nov 2024

Individuals with less efficient learning mechanisms benefit more from brain stimulation

As we age, our cognitive and motor functions deteriorate, which in turn affects our independence and overall quality of life.

27 Nov 2024

Woman’s saliva could offer clues to stress and mental health during pregnancy

New research out of Michigan State University found that the number and type of microbes present in the saliva of pregnant women differ according to whether they are experiencing life stress and symptoms of anxiety, depression and post-traumatic stress disorder.

27 Nov 2024

Small increases in physical activity could promote healthy longevity

If everyone in the United States population was as active as the top 25 per cent, individuals over the age of 40 could add five years to their life, according to a new study led by Griffith University researchers.

27 Nov 2024