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MR1 molecule and vitamin B6 could unlock new paths for cancer immunotherapy

Effective immunity hinges on the ability to sense infection and cellular transformation. In humans, there is a specialized molecule on the surface of cells termed MR1.

27 Nov 2024

Epigenetic profiles of blood cancer cells could aid in diagnosis and treatment

Research in biomedical laboratories has been changing significantly in recent years, to the point that test tubes have given way to computers on many occasions.

27 Nov 2024

McMaster University develops fast and easy test for bacteria detection in fluids

A novel new test for bacteria in fluids makes it as easy as observing a color change to confirm the presence of disease-causing pathogens, promising much easier diagnostic tests and greater food safety.

26 Nov 2024

Late-liver-stage malaria vaccine delivers 89% protection and boosts cellular immunity

Genetically attenuated malaria parasites with extended liver-stage arrest (GA2) showed 89% protection in a clinical trial, surpassing earlier vaccine candidates and highlighting the potential of cellular immunity.

26 Nov 2024

Rising waters, rising risks: The health impact of climate-driven floods

Flooding, driven by climate change, poses escalating health risks globally, disproportionately affecting vulnerable populations while demanding innovative prevention, preparedness, and recovery strategies.

26 Nov 2024

Placental defects linked to congenital heart defects

Congenital heart defects are the most common form of human birth defect, but we still don't fully understand what causes them.

26 Nov 2024

Mitochondrial energy shutdown triggers inflammatory response instead of cell death

Whether cells in the human body survive or die under stress depends, among other things, on their mitochondria.

26 Nov 2024

Study reveals how liver bile composition changes during enteric infections

Intestinal infections can change the composition of liver bile, leading to changes in immune function and gut bacteria, potentially helping fight off harmful bacteria .

26 Nov 2024

Scientists decode ovarian aging with groundbreaking molecular atlas

Researchers unveil a comprehensive multi-omics atlas of ovarian aging, highlighting coordinated gene expression changes, mTOR signaling, and cellular communication as key to understanding fertility decline.

26 Nov 2024

How public forests in the U.S. nourish and heal millions

Forests in the U.S. provide over 255,000 metric tons of food and medicines annually, sustaining millions through wild harvesting and grazing, with profound cultural, nutritional, and economic benefits.

26 Nov 2024

Growing gulf in US life expectancy deepened by COVID-19 pandemic

Researchers update their analysis from the original Eight Americas study to reflect current life expectancy disparities in the United States.

26 Nov 2024

Machine learning tool detects early signs of Alzheimer's in mice

Subtle signs of Alzheimer's disease can emerge decades before a diagnosis - often in the form of irregular behaviors that reflect very early stages of brain dysfunction.

26 Nov 2024

Specific protein patterns can predict IBD up to 16 years before diagnosis

Scientists at örebro University have identified specific protein patterns in blood that can predict inflammatory bowel disease (IBD) up to 16 years before diagnosis.

26 Nov 2024

Study shows cancers are uniformly growing masses

Researchers at the University of Cologne and the Centre for Genomic Regulation (CRG) in Barcelona have discovered that cancer grows uniformly throughout its mass, rather than at the outer edges.

26 Nov 2024

Research shows impact of concussions on aperiodic brain activity

A new study of high school football players found that concussions affect an often-overlooked but important brain signal.

26 Nov 2024

Coffee reshapes Brazilian diets: sugar up, milk down, and health risks highlighted

Coffee consumption in Brazil influences dietary choices, increasing sugar and sweetener intake while reducing milk and sugar-sweetened beverage consumption, with notable gender differences and public health implications.

25 Nov 2024

Atlas maps plasma proteins to transform disease diagnosis and treatment

Researchers have developed the most comprehensive atlas linking plasma proteins to diseases and traits in over 53,000 individuals, offering groundbreaking insights for precision medicine. This resource uncovers 168,100 protein-disease associations and identifies new therapeutic targets.

25 Nov 2024