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Genetically engineered cartilage delivers anti-inflammatory drug in response to knee activity

Working to develop new treatments for osteoarthritis, researchers at Washington University School of Medicine in St. Louis have genetically engineered cartilage to deliver an anti-inflammatory drug in response to activity similar to the bending of a knee or other motions that put stress on joints.

27 Jan 2021

Miniaturized brush tested as a possible technique for loosening cells from walls of pancreatic cysts

In a potential step forward for early pancreatic cancer diagnosis, a miniaturized brush was successfully tested as a possible technique for loosening cells from the walls of pancreatic cysts.

27 Jan 2021

Study shows the limits of working memory in younger children

Imagine a 7-year-old and a college student both take a break from their virtual classes to get a drink of water.

27 Jan 2021

IU researchers identify how breast cancer cells evade immune attacks

Researchers at the Indiana University Melvin and Bren Simon Comprehensive Cancer Center have identified how breast cancer cells hide from immune cells to stay alive. The discovery could lead to better immunotherapy treatment for patients.

27 Jan 2021

Cleveland Clinic receives two grants to study therapeutic potential of anti-cancer drug in Alzheimer's

The National Institute of Aging, part of the National Institutes of Health, and the Alzheimer's Drug Discovery Foundation awarded five-year grants of $3.2 million and $1.4 million, respectively, to scientists from Cleveland Clinic Lou Ruvo Center for Brain Health to study the therapeutic potential of the anti-cancer drug lenalidomide in early-stage Alzheimer's disease, known as mild cognitive impairment.

27 Jan 2021

Vaccines delivered via skin may offer better protection against respiratory diseases

Among infectious diseases that have caused pandemics and epidemics, smallpox stands out as a success story. Smallpox vaccination led to the disease's eradication in the twentieth century.

27 Jan 2021

Study uncovers a novel promising target for diabetes treatment

Researchers have discovered a novel and druggable insulin inhibitory receptor, named inceptor. The latest study from Helmholtz Zentrum Muenchen, the Technical University of Munich and the German Center for Diabetes Research is a significant milestone for diabetes research as the scientific community celebrates 100 years of insulin and 50 years of insulin receptor discovery.

27 Jan 2021

New model could help clinicians to safely allow two patients to share a single ventilator

As Covid-19 continues to put pressure on healthcare providers around the world, engineers at the University of Bath have published a mathematical model that could help clinicians to safely allow two people to share a single ventilator.

27 Jan 2021

Study provides evidence to support the "volume loss" theory of facial aging

For many of us, as we get older the skin on our face begins to sag and we seem to lose volume around our eyes, cheeks and chin.

27 Jan 2021

Biliverdin shields SARS-CoV-2 from host antibody response, study finds

A team of international scientists has recently revealed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) interacts with two heme metabolites, bilirubin and biliverdin, to escape the antibody-mediated host immune responses.

27 Jan 2021

Anakinra shows therapeutic potential in critically ill COVID-19 patients

A team of international scientists recently conducted an open-level clinical trial to investigate the effects of personalized immunotherapy on critically ill COVID-19 patients.

27 Jan 2021

CDC researchers back U.S. school re-openings but with strict COVID-19 regulations

As the U.S. continues to grapple with surging cases and the complex logistics of mass vaccination, is the country in a position to fully re-open its schools for in-person learning? Researchers at the Centers for Disease Control and Prevention (CDC) think so – notwithstanding a few very important caveats.

27 Jan 2021

Study: TALEN is five times more efficient than CRISPR-Cas9 in tightly packed DNA

Researchers used single-molecule imaging to compare the genome-editing tools CRISPR-Cas9 and TALEN.

27 Jan 2021

Could spironolactone treat COVID-19-related pneumonia and pulmonary fibrosis?

Researchers have described the potential of the drug spironolactone, a potassium-sparing diuretic, and anti-androgen, in preventing or alleviating the severity of COVID-19 pneumonia, and in preventing pulmonary fibrosis.

27 Jan 2021

What do we know about the SARS-CoV-2 vaccines so far?

A new study surveys what we know so far about SARS-CoV-2 vaccine candidates from advanced clinical trials.

27 Jan 2021

New method replicates bone tissue complexity, bone remodeling processes

A multidisciplinary team of researchers at the University of Massachusetts Amherst's Institute for Applied Life Sciences (IALS) have developed a technique to replicate bone tissue complexity and bone remodeling processes.

27 Jan 2021

Certain malaria parasites use a mechanism to cross the blood–brain barrier

Malaria is one of the most common causes of death in children in Africa and is triggered by a small parasite that lives in the blood. When the parasite builds up in the blood vessels of the brain, it develops into one of the most dangerous forms of the disease, cerebral malaria.

27 Jan 2021

Inflammation of the brain gray matter decreases nerve-cell activity in mouse model

Damage to the brain gray matter plays an important role in the progression of multiple sclerosis. This study now shows that such damage can be caused by inflammatory reactions that lead to loss of synapses, which impairs neural activity.

27 Jan 2021

Melatonin reduces cysts in the renal tubules of fruit flies

A hormone commonly associated with sleep-wake regulation has been found to reduce cysts in fruit flies, according to Concordia researchers. It's a finding that may affect the way we treat some kidney diseases and reduce the need for kidney transplants.

27 Jan 2021

New data shows that mINDY gene is involved in blood pressure regulation

Authors from the German Center for Diabetes Research (DZD) presented data showing that the longevity gene mammalian Indy (mINDY) is involved in blood pressure regulation in the Journal of Clinical Investigation (JCI) insight.

27 Jan 2021

Medical Science News

Genetically engineered cartilage delivers anti-inflammatory drug in response to knee activity

Miniaturized brush tested as a possible technique for loosening cells from walls of pancreatic cysts

Study shows the limits of working memory in younger children

IU researchers identify how breast cancer cells evade immune attacks

Cleveland Clinic receives two grants to study therapeutic potential of anti-cancer drug in Alzheimer's

Vaccines delivered via skin may offer better protection against respiratory diseases

Study uncovers a novel promising target for diabetes treatment

New model could help clinicians to safely allow two patients to share a single ventilator

Study provides evidence to support the "volume loss" theory of facial aging

Biliverdin shields SARS-CoV-2 from host antibody response, study finds

Anakinra shows therapeutic potential in critically ill COVID-19 patients

CDC researchers back U.S. school re-openings but with strict COVID-19 regulations

Study: TALEN is five times more efficient than CRISPR-Cas9 in tightly packed DNA

Could spironolactone treat COVID-19-related pneumonia and pulmonary fibrosis?

What do we know about the SARS-CoV-2 vaccines so far?

New method replicates bone tissue complexity, bone remodeling processes

Certain malaria parasites use a mechanism to cross the blood–brain barrier

Inflammation of the brain gray matter decreases nerve-cell activity in mouse model

Melatonin reduces cysts in the renal tubules of fruit flies

New data shows that mINDY gene is involved in blood pressure regulation

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

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