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Cell-by-cell analysis reveals brain changes in Tourette syndrome

In the first comprehensive, cell-by-cell analysis of brain tissue from individuals with Tourette syndrome, researchers have pinpointed exactly which cells are perturbed and how they malfunction, revealing how different types of brain cells are affected by the condition.

9 Apr 2025

Neural organoids offer insight into mechanisms of dementia

Researchers at The Ohio State University Wexner Medical Center and College of Medicine have discovered a new way that neurons act in neurodegeneration by using human neural organoids – also known as "mini-brain" models – from patients with frontotemporal lobar degeneration (FTLD).

9 Apr 2025

What happens if you significantly increase dietary folic acid intake?

Increased dietary folic acid intake may lead to adverse health effects, including inflammation and neurotoxicity, highlighting the need for optimal levels.

9 Apr 2025

Early-life ozone exposure linked to increased risk of childhood asthma and wheezing

Researchers investigate the impact of early-life ozone exposure on asthma and wheezing in children alone and in combination with other air pollutants.

9 Apr 2025

Male-female pairs of mice show resilience in coordinating fear responses

When faced with a potential threat, mice often freeze in place. Moreover, when two animals are together, they typically freeze at the same time, matching each other's periods of immobility.

9 Apr 2025

QRICH1 protein discovery opens new avenues for cancer and autoimmune therapies

In a study of the immune systems of mice, scientists at Johns Hopkins Medicine say they have found a new role for a protein, QRICH1, which could become a target for drugs to dial up or down the activation of T cells to fight cancers and autoimmune diseases.

9 Apr 2025

Study reveals how the brain processes active and passive touch differently

Though the sense of touch underlies how we and most other animals interact with the world around us, much remains unknown about how this sense is processed in the brain.

9 Apr 2025

Breakthrough nanoparticle delivery method targets brain inflammation for multiple conditions

Oregon State University researchers have discovered a way to get anti-inflammatory medicine across the blood-brain barrier, opening the door to potential new therapies for a range of conditions, including Alzheimer's disease, multiple sclerosis, Parkinson's disease and cancer cachexia.

9 Apr 2025

Can nature-based therapies heal people and the planet? Study investigates holistic solutions

Researchers at Swansea University have developed a protocol for a scoping review to explore how nature-based interventions influence individual, collective, and planetary well-being.

9 Apr 2025

IL-12 cytokine factory demonstrates success in targeting hard-to-treat cancers

A team of researchers from the Rice Biotech Launch Pad at Rice University has developed an implantable "cytokine factory" that safely triggers potent immune responses against hard-to-treat cancers, including metastatic melanoma, pancreatic and colorectal tumors.

8 Apr 2025

Food-as-medicine could save billions in healthcare costs—here’s what’s standing in its way

Researchers review how Food-as-Medicine (FAM) interventions can improve health, reduce healthcare costs, and reshape food production systems. They emphasize the urgent need for clinical validation before scaling individualized nutrition solutions.

8 Apr 2025

New drug compound prevents long COVID symptoms in mice

Researchers have shown a new drug compound can prevent long COVID symptoms in mice – a landmark finding that could lead to a future treatment for the debilitating condition.

8 Apr 2025

New discovery promises to revolutionize liver organoid development

Organoids are small-scale models that mimic human organs. These models could help scientists understand diseases and test treatments, and potentially aid in regenerative therapeutic methods.

8 Apr 2025

Anxiety fuels emotional eating and weight gain, study finds

Emotional eating and body dissatisfaction mediate links between BMI changes and mental health. These psychosocial factors explain how anxiety, depression, and weight gain interrelate over time.

8 Apr 2025

Experimental drug NU-9 shows promise for Alzheimer's and ALS treatment

Experimental drug NU-9 - a small molecule compound approved by the U.S. Food and Drug Administration (FDA) for clinical trials for the treatment of amyotrophic lateral sclerosis (ALS) - improves neuron health in animal models of Alzheimer's disease, according to a new Northwestern University study.

8 Apr 2025

Cutting carbs, not calories, may be key to better metabolic health

The intermittent fasting diet, which involves periods of severe calorie restriction, may be on the way out, as new research from the University of Surrey is suggesting that rather than drastically reducing calories, people can achieve similar metabolic benefits by cutting back on carbs.

8 Apr 2025