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Research shows IQGAP1 as a common target in variants of triple negative breast cancer

The cover for issue 26 of Oncotarget features Figure 6, "Mislocalization of IQGAP1-BRCA1 in human TNBC tumors phenocopies the dominant mutants and the TNBC cells," by Osman, et al. and reported that IQGAP1 is a signaling scaffold implicated in TNBC, but its mechanism is unknown.

30 Jun 2020

Novel brain pathology could improve diagnosis, treatment of neurodegenerative diseases

Bristol scientists have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington's disease.

30 Jun 2020

A semi-empirical model to reproduce the brain states from wakefulness to deep sleep

The human brain is a complex system comprising 1010 non-linear units (neurons) that interact in 1015 sites (synapses).

30 Jun 2020

Scientists discover mechanism involving key protein that predicts cancer progression and relapse

Cancer cases have been rising over the years and according to the statistics, the number of people living with cancer will continue to increase.

30 Jun 2020

Researchers uncover a potentially promising strategy to target brain tumors

Gliomas with mutations in what are called the isocitrate dehydrogenase (IDH) genes are the most common brain tumors diagnosed in younger adults aged 18 to 45 years.

30 Jun 2020

SARS-CoV-2 can infect heart cells in a lab dish, study shows

A new study shows that SARS-CoV-2, the virus that causes COVID-19 (coronavirus), can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus.

30 Jun 2020

A biocompatible polymer can help heal broken bones

Healing broken bones could get easier with a device that provides both a scaffold for the bone to grow on and electrical stimulation to urge it forward, UConn engineers reported on June 27 in the Journal of Nano Energy.

30 Jun 2020

COVID-19 patients' blood can help identify people at greatest risk of severe illness

Doctors can examine COVID-19 patients' blood to identify those at greatest risk of severe illness and to pinpoint those most likely to need a ventilator, new research from the University of Virginia School of Medicine suggests.

30 Jun 2020

COVID-19 triggers changes in blood platelets

Changes in blood platelets triggered by COVID-19 could contribute to the onset of heart attacks, strokes, and other serious complications in some patients who have the disease, according to University of Utah Health scientists.

30 Jun 2020

Novel vaccine that removes aged immune cells mitigates metabolic disorders in obese mice

Aging is a multifaceted process that affects our bodies in many ways. In a new study, researchers from Osaka University developed a novel vaccine that removes aged immune cells and then demonstrated an improvement of diabetes-associated metabolic derangements by vaccinating obese mice.

30 Jun 2020

Stool microbial and metabolite signatures predict cirrhosis

Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide, affecting an estimated one-quarter of the global population. It is a progressive condition that, in worst cases, can lead to cirrhosis, liver cancer, liver failure and death.

30 Jun 2020

Glowing dye may illuminate tumors during surgery

"Clean margins" are a goal of cancer excision surgery. If even a small piece of cancerous tissue is left behind, it increases the likelihood of a local recurrence and spread of the disease, possibly reducing overall survival time.

30 Jun 2020

Children from 8 years spontaneously link voice to facial emotion

Do children have to wait until age 8 to recognize - spontaneously and without instructions - the same emotion of happiness or anger depending on whether it is expressed by a voice or on a face?

30 Jun 2020

New vaccination strategy targets toxic molecules released by all Staphylococcal bacteria

Experiments in mice have shown early success in vaccinating them against potentially deadly bacterial infections, such as methicillin-resistant Staphylococcal aureus, or MRSA, the strain resistant to most drug treatments.

30 Jun 2020

SAFB1 may be a diagnostic marker for neurodegenerative diseases, shows study

Bristol scientists have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington's disease.

30 Jun 2020

Researchers identify new step in brain cell mechanism that shows promise for treating epilepsy

Researchers have identified a critical new step in how brain cells function in people with one of the most common forms of epilepsy.

30 Jun 2020

Newly identified molecules can help develop COVID-19 therapeutics

SARS-CoV-2, the coronavirus causing the global COVID-19 pandemic, uses a protein called polymerase to replicate its genome inside infected human cells.

30 Jun 2020

Researchers develop new coatings for implants to make them more compatible

New coatings on implants could help make them more compatible. Researchers at the Martin Luther University Halle-Wittenberg (MLU) have developed a new method of applying anti-inflammatory substances to implants in order to inhibit undesirable inflammatory reactions in the body.

30 Jun 2020

Glitches in DNA replication have important implications for treating cancer

USC researchers peering deep inside a living cell have discovered something surprising: Its system for preventing genetic damage linked to diseases can fail so badly that the cell would be better off without it.

30 Jun 2020

Engineered immune cells attack solid-tumor cancer cells from humans and mice

A method known as CAR-T therapy has been used successfully in patients with blood cancers such as lymphoma and leukemia.

30 Jun 2020

Medical Science News

Research shows IQGAP1 as a common target in variants of triple negative breast cancer

Novel brain pathology could improve diagnosis, treatment of neurodegenerative diseases

A semi-empirical model to reproduce the brain states from wakefulness to deep sleep

Scientists discover mechanism involving key protein that predicts cancer progression and relapse

Researchers uncover a potentially promising strategy to target brain tumors

SARS-CoV-2 can infect heart cells in a lab dish, study shows

A biocompatible polymer can help heal broken bones

COVID-19 patients' blood can help identify people at greatest risk of severe illness

COVID-19 triggers changes in blood platelets

Novel vaccine that removes aged immune cells mitigates metabolic disorders in obese mice

Stool microbial and metabolite signatures predict cirrhosis

Glowing dye may illuminate tumors during surgery

Children from 8 years spontaneously link voice to facial emotion

New vaccination strategy targets toxic molecules released by all Staphylococcal bacteria

SAFB1 may be a diagnostic marker for neurodegenerative diseases, shows study

Researchers identify new step in brain cell mechanism that shows promise for treating epilepsy

Newly identified molecules can help develop COVID-19 therapeutics

Researchers develop new coatings for implants to make them more compatible

Glitches in DNA replication have important implications for treating cancer

Engineered immune cells attack solid-tumor cancer cells from humans and mice

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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