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Mitochondrial DNA variant predicts resistance to melanoma immunotherapy

Results from a new study help resolve the decade-long mystery of why many patients with the deadliest form of skin cancer do not respond to the latest cancer treatments.

6 Jun 2025

New technique creates multimeric aptamers for precision virus targeting

We have all heard of antibodies – proteins produced by our bodies to bind to viruses or bacteria, marking them for elimination by the immune system.

6 Jun 2025

Study aims to demystify the immune toxicity triggered by osimertinib-ICI co-treatment

Non-small cell lung cancer (NSCLC) accounts for the majority of lung cancer cases and remains a leading cause of cancer mortality worldwide.

6 Jun 2025

Oncologists push for age inclusive use of cancer treatments

Recent advances have resulted in highly effective "tissue-agnostic" drugs that treat cancers based on their molecular markers rather than their tissue of origin, but very few of these drugs are approved for use in children.

6 Jun 2025

Stanford scientists grow vascularized heart and liver organoids

For over a decade, scientists have been growing organoids - small clusters of cells that mimic a particular organ - to serve as miniature biological models.

6 Jun 2025

Taurine levels found unreliable as a biomarker of aging

Scientists at the National Institutes of Health (NIH) have found that levels of circulating taurine, a conditionally essential amino acid involved in multiple important biological functions, is unlikely to serve as a good biomarker for the aging process.

6 Jun 2025

Study uncovers brain regions that help differentiate imagination from reality

Areas of the brain that help a person differentiate between what is real and what is imaginary have been uncovered in a new study led by UCL researchers.

6 Jun 2025

Overexpression of two long non-coding RNAs identified in gastric cancer

A new research paper was published in Volume 16 of Genes & Cancer on May 9, 2025, titled "Evaluation of LncRNAs CBR3-AS1 and PCA3 expression in Gastric cancer and their correlation to clinicopathological variables."

6 Jun 2025

Eating more pulses and vegetables lowers stress by boosting beneficial gut bacteria, study finds

Higher diet quality, especially with more pulses and vegetables, was linked to greater Lachnospira abundance in the gut and lower stress scores among Japanese adults. The relationship appears to be mediated by specific gut bacteria rather than a direct effect of diet on stress.

6 Jun 2025

Generative AI system from Northwestern doubles radiology efficiency

A first-of-its-kind generative AI system, developed in-house at Northwestern Medicine, is revolutionizing radiology - boosting productivity, identifying life-threatening conditions in milliseconds and offering a breakthrough solution to the global radiologist shortage, a large new study finds.

6 Jun 2025

Scientists identify genetic clues linking air pollution to neurodegeneration

This review highlights how air pollution and occupational inhalation exposures may contribute to neurodegenerative disorders by triggering epigenetic changes. The authors stress the urgent need for advanced research to identify early biomarkers and guide protective health strategies for high-risk populations.

6 Jun 2025

Healthy diet improves metabolism even without weight loss

Nearly one-third of people who adopted and adhered to a healthy diet did not lose any weight, but still reaped many health benefits, according to a new study led by researchers at Harvard T.H. Chan School of Public Health and Ben Gurion University, Israel.

6 Jun 2025

New retinal prosthesis restores vision in blind mice and detects near-infrared light in macaques

A new prosthesis for the retina weaved with nanowires partially restored vision in blind mice and allowed detection of near-infrared light in macaques, according to a new study.

6 Jun 2025

Maternal exposure to metals rewires infants’ gut and resistance genes

Prenatal exposure to trace elements like selenium, copper, and arsenic can significantly alter the infant gut microbiome, metabolism, and antibiotic resistance gene patterns. These changes appear as early as three months and evolve during the first year of life.

5 Jun 2025

New Japanese database reveals how gut microbes and diet connect

Researchers have launched the NIBN Japan Microbiome Database, featuring over 2,000 gut microbiome profiles from healthy Japanese adults with extensive lifestyle and dietary metadata. This resource aims to accelerate microbiome-health research and enable precision medicine insights.

5 Jun 2025

Breakthrough drug delivery system transports genetic therapies directly to the lungs

Scientists have made a key breakthrough for treating respiratory diseases by developing a new drug delivery system that transports genetic therapies directly to the lungs, opening promising possibilities for patients with conditions like lung cancer and cystic fibrosis.

5 Jun 2025