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Rethinking the germ theory: A balanced take on microbes and disease outcomes

Review explores the complexities of infectious disease outcomes through a balanced perspective, emphasizing the interplay between pathogenic microbes and host conditions, challenging the traditional germ-disease theory by proposing a more integrated view that considers both pathogen virulence and host immunity's impact on disease manifestation.

10 Apr 2024

Study shows GHRH antagonist's role in AML drug resistance

A new research paper was published in Oncotarget's Volume 15 on April 8, 2024, entitled, "Exploring the role of GHRH antagonist MIA-602 in overcoming Doxorubicin-resistance in acute myeloid leukemia."

10 Apr 2024

New lab assay could make diagnosis and treatment of lung cancer easier

A new lab assay developed by researchers at Fred Hutch Cancer Center could make diagnosis and treatment of small-cell lung cancer and non-small cell lung cancer easier.

10 Apr 2024

New generative AI tool models the infant microbiome

The gut microbiome has a profound impact on the health and development of infants. Research shows that dysbiosis-;or imbalances in the microbial community-;is associated with gastrointestinal diseases and neurodevelopmental deficits.

10 Apr 2024

Researchers create novel drug that can prevent flu-induced lung injury

Infection with the influenza virus leads to lung injury through inflammation over-activation that causes collateral damage to cells required for breathing.

10 Apr 2024

Study unlocks how cortisone activates the body’s natural “brakes” on inflammation

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions.

10 Apr 2024

Human-wildlife interface: Starling movements linked to E. coli carriage

Research unveils how spotless starlings' movements, monitored via GPS, relate to the carriage and potential spread of Escherichia coli (E. coli), emphasizing the significant role of bird movement patterns in transmitting pathogens across different environments.

10 Apr 2024

New sleep-enhancing nutraceutical blend falls short in clinical trial

Study investigates the impact of a unique nutraceutical blend, combining L-theanine with valerian, saffron, and lemon balm extracts, on improving sleep quality, finding no significant difference compared to a placebo in individuals experiencing poor sleep.

10 Apr 2024

Unraveling the complex web of rectal infections and the microbiome in MSM

Study delves into the relationships between various sexually transmitted infections, including Neisseria gonorrhoeae, Chlamydia trachomatis, Torquetenovirus, and high-risk HPV, and their effects on the anorectal microbiome among men who have sex with men (MSM), unveiling complex interactions that may influence infection outcomes and treatment strategies.

10 Apr 2024

Study reveals unexpected vulnerability of lung immune cells to SARS-CoV-2

The lung-cell type that's most susceptible to infection by SARS-CoV-2, the virus that causes COVID-19, is not the one previously assumed to be most vulnerable.

10 Apr 2024

Sugar abnormalities in the blood may promote biological aging and inflammation in HIV patients

The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., along with his team and collaborators, has identified sugar abnormalities in the blood that may promote biological aging and inflammation in people living with HIV (PLWH).

10 Apr 2024

New natural supplement shows promise in preventing postpartum blues

A new study published in the Lancet discovery science journal eClinicalMedicine has confirmed that a novel natural supplement-;invented, researched, developed and commercialized at the Centre for Addiction and Mental Health (CAMH)-;prevents postpartum blues, and reduces symptoms of postpartum depression over the following six months after giving birth.

10 Apr 2024

Study sheds light on the significance of glucocorticoid receptor in drug-resistant prostate cancer

New research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by limiting the activity of coregulator proteins.

10 Apr 2024

Novel immune cell therapy may be a promising strategy for combating HBV infection

Chronic infection with the hepatitis B virus (HBV) causes progressive liver problems, and eradication of the virus remains a formidable challenge.

10 Apr 2024

Probiotics plus vitamin D supplements may improve cognitive function in individuals with schizophrenia

Previous studies have questioned whether gut microbe imbalances and vitamin D deficiency may be linked to schizophrenia.

10 Apr 2024

Integrating machine learning and gait analysis into orthopedic practice can lead to more effective care

Investigators have applied artificial intelligence techniques to gait analyses and medical records data to provide insights about individuals with leg fractures and aspects of their recovery.

10 Apr 2024

New evidence-based strategy for surgeons to sustain lifelong competency

As millions of Americans approach age 66, they face the inevitable question, is it time to retire? The physician population is aging alongside the general population – more than 40% of physicians in the U.S. will be 65 years or older within the next decade.

10 Apr 2024

Deciphering cancer plasticity:Insights from MSK research

About 90% of deaths from cancer are a result of metastasis -; that is, from cancer's ability to spread from an initial primary tumor to seed new tumors throughout the body, often in the lungs, liver, and brain.

10 Apr 2024

Enhancer-gene mapping with SCENT method offers insights into disease mechanisms

Genetic studies of diseases map segments of the genome driving disease. But to understand how those changes contribute to disease progression, it is important to understand how they may alter gene regulation of disease genes in cell populations assumed to be driving disease.

10 Apr 2024

Avian flu's leap to humans: Understanding risks and prevention strategies

Comprehensive report by the EFSA and ECDC delves into the factors that could prompt an avian influenza virus to evolve and potentially spark a pandemic, emphasizing the One Health approach for effective prevention and risk mitigation strategies.

10 Apr 2024