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Collaborative Frontiers grant to help predict behavior of the brain under metabolic stress

More than 30 million Americans have diabetes, with the vast majority having Type 2 disease. Characterized by insulin resistance and persistently high blood sugar levels, poorly controlled Type 2 diabetes has a host of well-recognized complications: compared with the general population, a greatly increased risk of kidney disease, vision loss, heart attacks and strokes, and lower limb amputations.

11 Dec 2019

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Huntington's disease (HD) is an incurable and fatal hereditary disease. Developing disease-modifying drugs to treat patients with HD depends on studying them in animal models. Scientists evaluated the mouse models used for developing new treatments for mood disorders in HD and recommended which of these models are most relevant to their studies.

11 Dec 2019

Study could help improve GENUS to become a therapeutic approach for Alzheimer's disease

The sweeping extent to which increasing 40Hz "gamma" rhythm power in the brain can affect the pathology and symptoms of Alzheimer's disease in mouse models has been surprising, even to the MIT neuroscientists who've pioneered the idea. So surprising, in fact, they can't yet explain why it happens.

11 Dec 2019

Researchers develop 'scar in a dish' model to closely mimic progressive organ scarring

Every organ in the body is capable, to some extent, of repairing itself after an injury. As part of this process, scar tissue forms and then recedes to make room for normal tissue when healing is complete.

11 Dec 2019

New therapy shows dramatic effect against worst types of leukaemias

A collaborative research effort by Australian and US scientists has led to the discovery of a promising new approach to treating some of the worst types of leukaemia, including an aggressive leukaemia that mostly affects babies.

11 Dec 2019

Researchers develop spray gel for frostbite injuries

Mountaineers and winter sports enthusiasts know the dangers of frostbite -- the tissue damage that can occur when extremities, such as the nose, ears, fingers and toes, are exposed to very cold temperatures. However, it can be difficult to get treated quickly in remote, snowbound areas.

11 Dec 2019

Study sheds light on the factors at play in neuroblastoma metastasis

Neuroblastoma can grow and spread in the body very aggressively, making it very difficult to treat. New research has shed important light on the factors at play in the metastasis of neuroblastoma, which could potentially lead to new treatment strategies.

11 Dec 2019

Nano-sized vesicles released by bacteria may protect against HIV infection

Nano-sized vesicles released by certain bacteria that inhabit the vagina may protect against HIV infection, suggests a study of human cells and tissues by researchers at the National Institutes of Health and the University of Bologna, Italy. Known as extracellular vesicles, these bubble-like particles are produced by many kinds of cells and are thought to transport molecules from one cell to another.

11 Dec 2019

New approach to alter intestinal microbiota and protect against inflammatory diseases

Targeted immunization against bacterial flagellin, a protein that forms the appendage that enables bacterial mobility, can beneficially alter the intestinal microbiota, decreasing the bacteria's ability to cause inflammation and thus protecting against an array of chronic inflammatory diseases, according to a new study by the Institute for Biomedical Sciences and the Neuroscience Institute at Georgia State University.

11 Dec 2019

Researchers use stem cells to create in-vitro 3D neural tissue model

Researchers at the University of Illinois at Urbana-Champaign have successfully used stem cells to engineer living biohybrid nerve tissue to develop 3D models of neural networks with the hopes of gaining a better understanding of how the brain and these networks work.

11 Dec 2019

Mice study shows the impact of taking antidepressants during pregnancy

Exposure to antidepressants during pregnancy and the first weeks of life can alter sensory processing well into adulthood, according to research in mice recently published in eNeuro.

From Society for Neuroscience 11 Dec 2019

Eating ice cream may cause you a headache

As opposed to making you happy, eating ice cream may cause you a headache. Cephalalgia, the official journal of the International Headache Society, published the article entitled "Prevalence and characteristics of headache attributed to ingestion or inhalation of a cold stimulus (HICS): A cross-sectional study", by Torsten Kraya and colleagues from the Department of Neurology, at Martin-Luther-University Halle-Wittenberg, and St. Georg Hospital, Leipzig, Germany.

10 Dec 2019

Fresh red blood cell transfusions are no more beneficial than older ones to critically ill children

A new study led by the Sainte-Justine University Hospital Centre and the University of Montreal, along with the Washington University School of Medicine in St. Louis, has found that transfusions using fresh red blood cells--cells that have spent seven days or less in storage--are no more beneficial than older red blood cells in reducing the risk of organ failure or death in critically ill children.

10 Dec 2019

Researchers find another piece of puzzle relating to bird flu viruses

Normally, bird flu viruses do not spread easily from person to person. But if this does happen, it could trigger a pandemic. Researchers from the MDC and RKI have now explained in the journal Nature Communications what makes the leap from animals to humans less likely.

10 Dec 2019

New joint venture aims to develop implantable cell therapies for debilitating conditions with no cure

Mayo Clinic and W. L. Gore & Associates Inc., a global materials science company, have formed a joint venture to advance the development of implantable cell therapies to treat debilitating conditions with no cure. Avobis Bio will combine Mayo Clinic's clinical and cell expertise and Gore's expertise in material sciences to address some of the most challenging medical issues.

10 Dec 2019

Justified and unjustified violence in movies activate different parts of adolescent brain

The gun violence seen in popular PG-13 movies aimed at children and teenagers has more than doubled since the rating was introduced in 1984. The increasing on-screen gun violence has raised concerns that it will encourage imitation, especially when it is portrayed as "justified."

10 Dec 2019

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

Cystic fibrosis is caused by an inherited mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

10 Dec 2019

Study provides most detailed classification of acute myeloid leukemia, myelodysplastic syndrome

Results from a study conducted by St. Jude Children's Research Hospital and the Munich Leukemia Laboratory were presented today as a late-breaking abstract at the American Society of Hematology annual meeting. The study integrates genomic and transcriptomic sequencing to provide the most detailed classification of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) to date.

10 Dec 2019

Researchers aim to exploit DNA mutations in the treatment of blood and bone marrow cancers

In a clinical trial led by Yale Cancer Center and Smilow Cancer Hospital, researchers aim to exploit DNA mutations in the treatment of two blood and bone marrow cancers, a different tacit than the more traditional approach of blunting or switching off genetic mutations linked to cancer.

10 Dec 2019

Yeasts derived from food can reduce multi-drug resistant fungal infections

A study by researchers in the United States and India has shown that probiotic yeasts derived from food are able to reduce the virulence of, and even prevent infections by, several types of fungi that are responsible for life-threatening infections in hospitalized and immune-compromised individuals, including the multi-drug resistant Candida auris, which was recently listed as an urgent threat by the U.S. Centers for Disease Control in its 2019 Antibiotic Resistance Threats report.

10 Dec 2019

Medical Science News

Collaborative Frontiers grant to help predict behavior of the brain under metabolic stress

Scientists evaluate mouse models used for developing new treatments for Huntington's disease

Study could help improve GENUS to become a therapeutic approach for Alzheimer's disease

Researchers develop 'scar in a dish' model to closely mimic progressive organ scarring

New therapy shows dramatic effect against worst types of leukaemias

Researchers develop spray gel for frostbite injuries

Study sheds light on the factors at play in neuroblastoma metastasis

Nano-sized vesicles released by bacteria may protect against HIV infection

New approach to alter intestinal microbiota and protect against inflammatory diseases

Researchers use stem cells to create in-vitro 3D neural tissue model

Mice study shows the impact of taking antidepressants during pregnancy

Eating ice cream may cause you a headache

Fresh red blood cell transfusions are no more beneficial than older ones to critically ill children

Researchers find another piece of puzzle relating to bird flu viruses

New joint venture aims to develop implantable cell therapies for debilitating conditions with no cure

Justified and unjustified violence in movies activate different parts of adolescent brain

Modifier gene offers a likely explanation for less infection in some patients with cystic fibrosis

Study provides most detailed classification of acute myeloid leukemia, myelodysplastic syndrome

Researchers aim to exploit DNA mutations in the treatment of blood and bone marrow cancers

Yeasts derived from food can reduce multi-drug resistant fungal infections

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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