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ALPK2 identified as promising new therapeutic target for treatment of heart failure

Tatsuya Yoshida, Mikito Takefuji, and Toyoaki Murohara in the Department of Cardiology, Nagoya University Graduate School of Medicine, identified an enzyme, alpha-kinase 2 (ALPK2) that is specifically expressed in the heart.

30 Jan 2025

Rapid blood test could identify brain bleeds from clot-caused strokes

A blood test may rapidly distinguish brain bleeds from clot-caused strokes, even before people with stroke symptoms reach the emergency room, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2025.

30 Jan 2025

Shorter telomeres linked to higher risk of age-related brain diseases

People with shorter protective caps at the end of their chromosomes (called telomeres) may be more likely to develop age-related brain diseases such as stroke, dementia and late-life depression (usually diagnosed at age 60 or older), according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2025.

30 Jan 2025

Stem cell-derived heart patches show promise for heart failure treatment

Innovative muscle patches derived from stem cells demonstrate efficacy in heart repair, improving function in primates and a human patient, with trials ahead.

30 Jan 2025

Can AI recognize the signs of depression in people’s voices?

Machine learning analysis of voice recordings shows promise for detecting depression, with over 70% accuracy, improving screening in healthcare settings.

30 Jan 2025

Cancer-fighting virus T-VEC helps shrink tough-to-treat skin tumors

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell composition with low adverse events.

30 Jan 2025

The key to healthy aging? Exercise might be the answer

Researchers explore the health benefits of physical activity in the elderly.

30 Jan 2025

Does taxing sugary drinks lead to health benefits?

Researchers identify a significant association between sugar-sweetened beverage tax and BMI changes among adults living in Berkeley, California.

30 Jan 2025

Researchers create high-performance artificial neurons for advanced perception systems

Artificially engineered biological processes, such as perception systems, remain an elusive target for organic electronics experts due to the reliance of human senses on an adaptive network of sensory neurons, which communicate by firing in response to environmental stimuli.

30 Jan 2025

New insights into mechanisms of mucosal mast cells in food allergies

Food allergy, or the aggressive immune system reaction following the consumption of a certain food or food ingredient, typically involves immunoglobulin E (IgE) antibodies and can be potentially life-threatening

29 Jan 2025

Targeting MYCN and MDM2 offers new hope for cancer therapy

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical reality.

29 Jan 2025

Climate change is pushing up rates of kidney disease and urological cancers

Climate change is increasing the risk of urological diseases, including cancer and kidney conditions, while urological healthcare itself contributes to environmental harm through high carbon emissions.

29 Jan 2025

Study reveals how glial cells respond to damage in neuron dendrites

Neurons may get all the glory, but they would be nothing without glial cells. While brain cells do the heavy lifting in the nervous system, it's the glia that provide nutrients, clean up waste, and protect neurons from harm.

29 Jan 2025

Bioengineers create non-invasive way to control cells using temperature

Imagine being at a big marquee event at an arena, like the Super Bowl, with the roar of the crowd, the smell of hot dogs, and a sea of jerseys all merging into one chaotic blur.

29 Jan 2025

Is juicing good for your gut? Research shows surprising microbiome changes

Short-term fruit and vegetable juicing causes microbial shifts in the oral and gut microbiome, but these changes are mostly transient and return to baseline after 14 days.

29 Jan 2025

From gut health to metabolism: How sleep controls more than you think

Study reveals that sleep traits predict over 15% of body characteristics across 15 physiological systems, with visceral fat, cardiovascular health, and metabolism deeply intertwined with sleep patterns.

29 Jan 2025

Can an online lifestyle plan keep your brain sharp? Research says yes

"Maintain Your Brain" study shows how a tailored online program can improve cognition and lower dementia risk—discover how simple lifestyle changes could protect your brain as you age.

29 Jan 2025

New AI tool promises faster vaccine development by predicting T cell epitopes

An exciting collaboration between the Ragon Institute and the Jameel Clinic at MIT has achieved a significant milestone in leveraging artificial intelligence (AI) to aid the development of T cell vaccine candidates.

29 Jan 2025

Researchers propose personalized probiotic therapies for inflammatory diseases

A new approach to treating inflammatory diseases through personalized probiotic therapies – also known as precision medicine – has been proposed by researchers at the University of Surrey.

29 Jan 2025

New compound Z526 combats cancer-associated cachexia in preclinical models

In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.

29 Jan 2025