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Researchers uncover mechanism that leads to disorders in pancreatic development, infant diabetes

Researchers at the University of Helsinki, Finland, have uncovered a mechanism through which a mutation in the STAT3 gene leads to a disorder in the development of the pancreas and to infant diabetes.

11 Apr 2017

Study identifies potential link between genes and treatment response in children with CAE

Consider two children who have childhood absence epilepsy (CAE), the most common form of pediatric epilepsy. They both take the same drug--one child sees an improvement in their seizures, but the other does not.

11 Apr 2017

Feinstein Institute research may lead to new treatment option for low-grade gliomas

Marc Symons, PhD, professor in The Feinstein Institute for Medical Research's Karches Center for Oncology Research, is examining if a common medication administered to treat pinworms, could replace the current treatment used for certain brain cancers.

11 Apr 2017

TSRI professor receives $4.8 million grant to advance potential HIV vaccine research

Professor Michael Farzan, co-chair of the Department of Immunology and Microbiology on the Florida campus of The Scripps Research Institute has received $4.8 million in funding through a 2017 Avant-Garde Award for HIV/AIDS research from the National Institutes of Health's National Institute on Drug Abuse.

11 Apr 2017

Duke researchers link specific differences in brain structure to multiple forms of mental disorder

A Duke University study is the first to link specific differences in brain structure to what is common across many types of mental illness.

11 Apr 2017

Scientists discover promising target to treat highly aggressive brain tumor in infants

Using state-of-the-art gene editing technology, scientists from Ann & Robert H. Lurie Children's Hospital of Chicago have discovered a promising target to treat atypical teratoid/rhabdoid tumor (AT/RT) – a highly aggressive and therapy resistant brain tumor that mostly occurs in infants.

11 Apr 2017

Researchers identify 26 novel genes linked to intellectual disability

Researchers at the Centre for Addiction and Mental Health and Queen's University have identified 26 new genes linked to intellectual disability. Currently most patients with intellectual disability receive no molecular diagnosis, which significantly affects their health and shortens their lifespan.

11 Apr 2017

JAX professor receives grant from National Eye Institute to study diseases of retinal pigment epithelium

The National Eye Institute has awarded Jackson Laboratory Professor Patsy Nishina, Ph.D., and Associate Professor Gregory Carter, Ph.D., a four-year grant totaling $2,414,304 to study diseases of the retinal pigment epithelium (RPE), with the goal of identifying druggable targets for age-related macular degeneration and other heritable retinal diseases.

11 Apr 2017

Antimicrobial protein reduces creamy white lesions linked to oral thrush in mouse models

An antimicrobial protein caused a dramatic reduction in the creamy white lesions associated with oral thrush in a preclinical study, report microbiologists with McGovern Medical School at The University of Texas Health Science Center at Houston.

11 Apr 2017

Activation of specific protein could lead to acute lymphoblastic leukemia, study reveals

The discovery of a protein signature that is highly predictive of leukemia could lead to novel treatments of the leading childhood cancer, according to new study showing that competition among certain proteins causes an imbalance that leads to leukemia.

11 Apr 2017

Metabolite produced by intestinal bacteria protects against type 2 diabetes, study shows

A high concentration of indolepropionic acid in the serum protects against type 2 diabetes, shows a new study from the University of Eastern Finland. Indolepropionic acid is a metabolite produced by intestinal bacteria, and its production is boosted by a fibre-rich diet.

11 Apr 2017

Identifying serious bowel conditions in under-50s

The fundamental problem is that the symptoms are very similar, or at least some are. Taking your example of IBS – this is characterised by abdominal pain, plus sometimes diarrhoea or constipation. Yet these are key symptoms of abdominal cancer!

11 Apr 2017

Scientists discover new role for autophagosomes in neurodegenerative diseases

Autophagosomes are at the center of attention, at least since the Nobel Prize for Medicine was awarded for research on autophagy in 2016. The much talked about autophagosomes are small membrane vesicles in charge of waste disposal to promote recycling of its components.

11 Apr 2017

Feeding status alters the human adipose tissue response to exercise, study reveals

Time and again, fitness enthusiasts have a question–to exercise before or after breakfast. A new study published online in the American Journal of Physiology—Endocrinology and Metabolism has highlighted the role of fat toward metabolism. This is the first study that reveals the effects of fasting and feed status on human adipose tissue responses to exercise.

11 Apr 2017

Scientists solve structure of protein crucial to reproduction and spread of Zika virus

Zika virus is a mosquito-borne infectious disease linked to certain birth defects in infants in South and Central America and the United States.

11 Apr 2017

Study reveals potential new therapeutic approach to tackle infection by Legionella bacteria

The precise mechanism used by Legionella bacteria to escape the body's defences has been unpicked in intricate detail and is described for the first time in the journal eLife.

11 Apr 2017

New study finds link between neural tube defects in infants and neurodegenerative diseases

A new study has found a link between neurological birth defects in infants commonly found in pregnant women with diabetes and several neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases.

10 Apr 2017

Miniature models of ‘womb lining’ could provide insights into early pregnancy and menstrual cycle

Scientists at the University of Cambridge have succeeded in growing miniature functional models of the lining of the womb (uterus) in culture.

10 Apr 2017

History of early life abuse may affect concentration abilities

Does a history of abuse before the age of 18 affect later capacity to concentrate and stay focused? According to a new study Veterans with a history of physical or sexual abuse or witnessing family violence before the age of 18 have a reduced ability to concentrate compared to Veterans who were not abused

10 Apr 2017

High level of protein appears to diminish energy burning power of brown fat

Too much of a protein already associated with prostate cancer appears to also diminish the energy burning power of brown fat, scientists report.

10 Apr 2017

Medical Science News

Researchers uncover mechanism that leads to disorders in pancreatic development, infant diabetes

Study identifies potential link between genes and treatment response in children with CAE

Feinstein Institute research may lead to new treatment option for low-grade gliomas

TSRI professor receives $4.8 million grant to advance potential HIV vaccine research

Duke researchers link specific differences in brain structure to multiple forms of mental disorder

Scientists discover promising target to treat highly aggressive brain tumor in infants

Researchers identify 26 novel genes linked to intellectual disability

JAX professor receives grant from National Eye Institute to study diseases of retinal pigment epithelium

Antimicrobial protein reduces creamy white lesions linked to oral thrush in mouse models

Activation of specific protein could lead to acute lymphoblastic leukemia, study reveals

Metabolite produced by intestinal bacteria protects against type 2 diabetes, study shows

Identifying serious bowel conditions in under-50s

Scientists discover new role for autophagosomes in neurodegenerative diseases

Feeding status alters the human adipose tissue response to exercise, study reveals

Scientists solve structure of protein crucial to reproduction and spread of Zika virus

Study reveals potential new therapeutic approach to tackle infection by Legionella bacteria

New study finds link between neural tube defects in infants and neurodegenerative diseases

Miniature models of ‘womb lining’ could provide insights into early pregnancy and menstrual cycle

History of early life abuse may affect concentration abilities

High level of protein appears to diminish energy burning power of brown fat

Exploring the nanoscale: How AFM is transforming cosmetic science

Innovating Texture and Culture in Plant-Based Foods

Advancing brain microphysiological systems (bMPS)

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