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Researchers find explanation for link between persistent infection and long-term immunity

Many infectious diseases are one and done; people get sick once and then they are protected from another bout of the same illness.

17 Jan 2017

Yale researchers discover how tick-borne bacteria cause infection

Before infecting humans, tick-borne bacteria or viruses first have to get past a tick's defenses to colonize it.

17 Jan 2017

Naturally-occurring compound can inhibit early formation of toxins linked to Parkinson's Disease

A naturally-occurring compound has been found to block a molecular process thought to underlie Parkinson's Disease, and to suppress its toxic products, scientists have reported.

17 Jan 2017

Knowledge bank approach could help find best treatment option for AML patients

An international collaboration led by clinical researchers at the Wellcome Trust Sanger Institute has shown proof-of-concept that truly personalised therapy will be possible in the future for people with cancer.

17 Jan 2017

Every meal triggers short-term inflammatory responses in healthy individuals

When we eat, we do not just take in nutrients - we also consume a significant quantity of bacteria. The body is faced with the challenge of simultaneously distributing the ingested glucose and fighting these bacteria.

17 Jan 2017

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Metastatic pancreatic cancer -- cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths -- changes its metabolism and is "reprogrammed" for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

16 Jan 2017

Functional deficits caused by mini-strokes can last longer than previously thought

Evidence overwhelmingly supports a link between cognitive decline and cerebrovascular diseases such as atherosclerosis, arteriolosclerosis, and cerebral amyloid angiopathy. Not only do individuals with cerebrovascular diseases have a much higher incidence of cortical microinfarcts (mini-strokes), but post-mortem histological and in vivo radiological studies also find that the burden of microinfarcts is significantly greater among people with vascular cognitive impairment and dementia (VCID) than in age-matched, non-demented individuals.

16 Jan 2017

Spectroscopy and computer help RUB scientists gain new insights into workings of protein switches

Using a combination of infrared spectroscopy and computer simulation, researchers at Ruhr-Universität Bochum have gained new insights into the workings of protein switches.

16 Jan 2017

Researchers discover underlying cause for formation of granulomas

Granulomas are tissue nodules of immune cells that occur in diseases such as tuberculosis and sarcoidosis and can damage many organs.

16 Jan 2017

New antibody design may pave way for treating diseases affecting the brain

Immunotherapy has proven to be effective against many serious diseases. But to treat diseases in the brain, the antibodies must first get past the obstacle of the blood-brain barrier.

16 Jan 2017

Nanoparticle exposure can trigger dormant viruses in lung tissue cells

Nanoparticles from combustion engines can activate viruses that are dormant in lung tissue cells. This is the result of a study by researchers of Helmholtz Zentrum München, a partner in the German Center for Lung Research, which has now been published in the journal 'Particle and Fibre Toxicology'.

16 Jan 2017

Impact of IBS on patients

The report reveals a quite alarming situation about the economic impact of IBS on healthcare system, society and patients themselves. In particular, it disclosed that there are a lot of hidden costs related to the utilization of healthcare resources by means of patients, frequently not recognized as IBS...

16 Jan 2017

Biomarker linked to depression during pregnancy and low birth weight in baby

Depression is very common during pregnancy, with as many as one in seven women suffering from the illness and more than a half million women impacted by postpartum depression in the U.S. alone.

12 Jan 2017

Study finds that T cells play important role in control of Zika infections

The worst of the global Zika virus outbreak may be over but many key questions remain, such as why the virus persists in certain tissues after the systemic infection has cleared; how does the immune system counteract the virus and protect against reinfection; what determines the likelihood of long-term complications?

12 Jan 2017

Endogenous retroviruses may have played significant role in development of the brain

Over millions of years retroviruses have been incorporated into our human DNA, where they today make up almost 10 per cent of the total genome.

12 Jan 2017

Concussions accelerate Alzheimer's disease-related brain atrophy and cognitive decline, research finds

New research has found concussions accelerate Alzheimer's disease-related brain atrophy and cognitive decline in people who are at genetic risk for the condition.

12 Jan 2017

Study reveals brain activity may be key to link between stress and heart disease

Increased activity in a deep-lying region of the brain called the amygdala is associated with a higher risk of heart attack and stroke, according to a study published in The Lancet. The amygdala is known to process emotions such as fear and anger and the finding sheds light on the possible mechanism by which stress can lead to cardiovascular disease (CVD), say the study authors.

12 Jan 2017

Scientists identify Smurf1 protein that plays role in autophagy of TB bacteria

UT Southwestern Medical Center researchers have identified a protein that is central to the immune system's ability to recognize and destroy the bacterium responsible for the global tuberculosis (TB) epidemic.

12 Jan 2017

Could pathogen infection really lead to Alzheimer’s?

New concepts of infectious disease are evolving with the realization that pathogens are key players in the development of progressive chronic diseases that originally were not thought to be infectious. Infection is well-known to be associated with numerous neurological diseases for which...

12 Jan 2017

AAN issues new guideline on mapping the brain before epilepsy surgery

Before epilepsy surgery, doctors may consider using brain imaging to locate language and memory functions in the brain instead of the more invasive procedure that is commonly used, according to a guideline published by the American Academy of Neurology in the January 11, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Jan 2017

Medical Science News

Researchers find explanation for link between persistent infection and long-term immunity

Yale researchers discover how tick-borne bacteria cause infection

Naturally-occurring compound can inhibit early formation of toxins linked to Parkinson's Disease

Knowledge bank approach could help find best treatment option for AML patients

Every meal triggers short-term inflammatory responses in healthy individuals

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Functional deficits caused by mini-strokes can last longer than previously thought

Spectroscopy and computer help RUB scientists gain new insights into workings of protein switches

Researchers discover underlying cause for formation of granulomas

New antibody design may pave way for treating diseases affecting the brain

Nanoparticle exposure can trigger dormant viruses in lung tissue cells

Impact of IBS on patients

Biomarker linked to depression during pregnancy and low birth weight in baby

Study finds that T cells play important role in control of Zika infections

Endogenous retroviruses may have played significant role in development of the brain

Concussions accelerate Alzheimer's disease-related brain atrophy and cognitive decline, research finds

Study reveals brain activity may be key to link between stress and heart disease

Scientists identify Smurf1 protein that plays role in autophagy of TB bacteria

Could pathogen infection really lead to Alzheimer’s?

AAN issues new guideline on mapping the brain before epilepsy surgery

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

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