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Hebrew University researchers pave way for development of new approaches to cure malaria

More than a million people die each year of malaria caused by different strains of the Plasmodium parasite transmitted by the Anopheles mosquito. The medical world has yet to find an effective vaccine against the deadly parasite, which mainly affects pregnant women and children under the age of five. By figuring out how the most dangerous strain evades the watchful eye of the immune system, researchers from the Hebrew University of Jerusalem have now paved the way for the development of new approaches to cure this acute infection.

4 Dec 2012

Linagliptin may reduce brain damage following stroke in type 2 diabetic patients

In a study in mice, scientists at Karolinska Institutet in Sweden have discovered a new potential therapy that may reduce brain damage following stroke in type 2 diabetic patients. The suggested drug is already approved for the treatment of type 2 diabetes. However, the scientists hope that this new results, presented in the scientific journal Diabetes, also opens up the possibility to decrease brain injury after stroke in other patient groups with a high stroke risk.

4 Dec 2012

psi-GSH prevents neurodegeneration associated with Alzheimer's in mouse model

Researchers at the University of Minnesota's Center for Drug Design have developed a synthetic compound that, in a mouse model, successfully prevents the neurodegeneration associated with Alzheimer's disease.

4 Dec 2012

New research finds bisphenol A in fetal liver tissues

New research from the University of Michigan School of Public Health found BPA, or bisphenol A, in fetal liver tissue, demonstrating that there is considerable exposure to the chemical during pregnancy.

4 Dec 2012

Researchers derive dopaminergic neurons from bone marrow stem cells in monkeys

Parkinson's disease is a degenerative disorder of the central nervous system that is characterized by tremors, rigidity, slowness of movement, and difficulty walking. It is caused by loss of the neurons that produce the neurotransmitter dopamine (known as dopaminergic neurons). One of the primary goals in Parkinson's disease research is to develop a replacement for dopaminergic neurons.

4 Dec 2012

New antibodies effective at preventing formation of toxic protein particles linked to Parkinson’s, AD

Antibodies developed by researchers at Rensselaer Polytechnic Institute are unusually effective at preventing the formation of toxic protein particles linked to Alzheimer's disease and Parkinson's disease, as well as Type 2 diabetes, according to a new study.

4 Dec 2012

Researchers describe role of calcium in ability of Yersinias to cause disease

A more than 50-year-old question has now been answered. Chemists and microbiologists at the Biological Chemistry Center at Umeå University in Sweden are now able to describe in detail the role of calcium in the ability of the plague bacterium Yersinias to cause disease.

4 Dec 2012

UI researchers develop neonatal piglet model to study micronutrient deficiencies

University of Illinois researchers have developed a model that uses neonatal piglets for studying infant brain development and its effect on learning and memory. To determine if the model is nutrient-sensitive, they have done some research on the effects of iron-deficient diets.

4 Dec 2012

Feeding probiotics to baby zebrafish accelerates their development into adulthood

Probiotics like those found in yogurt are not only good for people--they are also good for fish. A new study by scientists at the Institute of Marine and Environmental Technology found that feeding probiotics to baby zebrafish accelerated their development and increased their chances of survival into adulthood.

4 Dec 2012

Link between stress and brain activation in patients with seizure

A study reported here at the 66th American Epilepsy Society Annual Meeting has identified a significant difference in the brain response to stress in patients who believe stress is an important factor in their seizure control compared to patients who do not hold this belief.

4 Dec 2012

Researchers identify 4 new genetic regions that influence birth weight

Researchers have identified four new genetic regions that influence birth weight, providing further evidence that genes as well as maternal nutrition are important for growth in the womb. Three of the regions are also linked to adult metabolism, helping to explain why smaller babies have higher rates of chronic diseases later in life.

4 Dec 2012

Researchers discover first-ever mouse model of diffuse idiopathic skeletal hyperostosis

Researchers at Western University have made a breakthrough that could lead to a better understanding of a common form of arthritis that, until now, has eluded scientists.

4 Dec 2012

Certain SSRI medications fail to achieve same selectivity for prevention of SUDEP

Scientists from Southern Illinois University today reported the results of a study evaluating the potential effect of two selective serotonin reuptake inhibitors (SSRI) antidepressant medications in reducing the risk of sudden unexpected death in epilepsy (SUDEP).

4 Dec 2012

Researchers discover 15 new genetic regions linked with coronary artery disease

The University of Ottawa Heart Institute (UOHI) participated in the largest genetic study of Coronary Artery Disease (CAD) to date. Researchers from the CARDIoGRAMplusC4D Consortium report the identification of 15 genetic regions newly associated with the disease, bringing to 46 the number of regions associated with CAD risk.

3 Dec 2012

Prrx1 component prevents cancer cells from lodging in other organs

Researchers discover that the cellular component Prrx1 prevents cancer cells from lodging in other organs and, therefore, generating new focuses of cancer.

3 Dec 2012

Scientists discover new target molecule for development of treatment against Alzheimer's

Scientists from VIB and KU Leuven have discovered a new target molecule for the development of a treatment against Alzheimer's disease. There is currently no cure for this disease.

3 Dec 2012

microRNAs play an important role during embryonic development

Sanford-Burnham researchers discover that microRNAs play an important role in germ layer formation-the process that determines which cells become which organs during embryonic development

3 Dec 2012

Researchers discover four new gene regions that contribute to low birth weight

An international team of genetics researchers has discovered four new gene regions that contribute to low birth weight. Three of those regions influence adult metabolism, and appear to affect longer-term outcomes such as adult height, risk of type 2 diabetes and adult blood pressure.

3 Dec 2012

Scientists identify 15 new genetic regions associated with coronary artery disease

Fifteen new genetic regions associated with coronary artery disease have been identified by a large, international consortium of scientists - including researchers at the Stanford University School of Medicine - taking a significant step forward in understanding the root causes of this deadly disease. The new research brings the total number of validated genetic links with heart disease discovered through genome-wide association studies to 46.

3 Dec 2012

Children with changes in bully genes have poor survival

In a genome sequencing study of 74 neuroblastoma tumors in children, scientists at the Johns Hopkins Kimmel Cancer Center and the Children's Hospital of Philadelphia (CHOP) found that patients with changes in two genes, ARID1A and ARID1B, survive only a quarter as long as patients without the changes. The discovery could eventually lead to early identification of patients with aggressive neuroblastomas who may need additional treatments.

3 Dec 2012

Medical Science News

Hebrew University researchers pave way for development of new approaches to cure malaria

Linagliptin may reduce brain damage following stroke in type 2 diabetic patients

psi-GSH prevents neurodegeneration associated with Alzheimer's in mouse model

New research finds bisphenol A in fetal liver tissues

Researchers derive dopaminergic neurons from bone marrow stem cells in monkeys

New antibodies effective at preventing formation of toxic protein particles linked to Parkinson’s, AD

Researchers describe role of calcium in ability of Yersinias to cause disease

UI researchers develop neonatal piglet model to study micronutrient deficiencies

Feeding probiotics to baby zebrafish accelerates their development into adulthood

Link between stress and brain activation in patients with seizure

Researchers identify 4 new genetic regions that influence birth weight

Researchers discover first-ever mouse model of diffuse idiopathic skeletal hyperostosis

Certain SSRI medications fail to achieve same selectivity for prevention of SUDEP

Researchers discover 15 new genetic regions linked with coronary artery disease

Prrx1 component prevents cancer cells from lodging in other organs

Scientists discover new target molecule for development of treatment against Alzheimer's

microRNAs play an important role during embryonic development

Researchers discover four new gene regions that contribute to low birth weight

Scientists identify 15 new genetic regions associated with coronary artery disease

Children with changes in bully genes have poor survival

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