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New insights into how MSCs ‘traffic’ from the circulation into tissues

Mesenchymal stem cells (MSCs), are a newly emerging cellular therapy being tested in approximately 250 clinical trials worldwide to help repair damaged tissues, such as injured heart muscle following a heart attack. The problem is that when culture-expanded MSCs are injected into the circulation, they have trouble gaining access to the inflamed tissues-exactly where their help is needed.

16 Nov 2012

New pathway appears to play a major role in information processing in the brain

Scientists at The Scripps Research Institute (TSRI) have identified a new pathway that appears to play a major role in information processing in the brain. Their research also offers insight into how imbalances in this pathway could contribute to cognitive abnormalities in humans.

16 Nov 2012

Oxytocin regulates social distance between women and men

Flirting brings women and men closer. But the "social distance" ensures that they will keep a certain spatial distance from each other. Researchers under the leadership of the University of Bonn studied whether this distance can be diminished by the so-called love hormone, oxytocin.

16 Nov 2012

Shear thinning hydrogels hold promise in treating many diseases, including cancer

Gels that can be injected into the body, carrying drugs or cells that regenerate damaged tissue, hold promise for treating many types of disease, including cancer. However, these injectable gels don't always maintain their solid structure once inside the body.

16 Nov 2012

GigaScience announces publication of whole-genome sequencing and analysis of Wuzhishan Pig

The international open-access journal GigaScience announces the publication of the whole-genome sequencing and analysis of the Wuzhishan Pig, an extensively inbred, miniature pig, which can serve as an excellent model for human medical research.

16 Nov 2012

D737 compound restores motor function and longevity in fruit flies with Alzheimer's

An efficient, high-volume technique for testing potential drug treatments for Alzheimer's disease uncovered an organic compound that restored motor function and longevity to fruit flies with the disease, according to new research that could help put the search for an effective Alzheimer's drug on a faster track.

16 Nov 2012

Researchers make groundbreaking discovery into optimization of light sources to human vision

Vision researchers at Barrow Neurological Institute have made a groundbreaking discovery into the optimization of light sources to human vision. By tuning lighting devices to work more efficiently with the human brain the researchers believe billions of dollars in energy costs could be saved.

16 Nov 2012

Study finds mechanism that mediates inhibition of critical breathing muscles during REM sleep

A novel brain mechanism mediating the inhibition of the critical breathing muscles during rapid eye movement (REM) sleep has been identified for the first time in a new study, offering the possibility of a new treatment target for sleep-related breathing problems.

16 Nov 2012

AGT2R gene variant may predispose women to pre-eclampsia

New research at the University of Adelaide has revealed a genetic link in pregnant mums - and their male partners - to pre-eclampsia, a life-threatening complication during pregnancy.

16 Nov 2012

Low levels of omega-3 may be behind postpartum depression

Low levels of omega-3 may be behind postpartum depression, according to a review lead by Gabriel Shapiro of the University of Montreal and the Research Centre at the Sainte-Justine Mother and Child Hospital.

16 Nov 2012

Freestyle rapping increases brain activity in the medial prefrontal cortex

Researchers in the voice, speech, and language branch of the National Institute on Deafness and Other Communication Disorders (NIDCD) at the National Institutes of Health (NIH) have used functional magnetic resonance imaging to study the brain activity of rappers when they are "freestyling" - spontaneously improvising lyrics in real time.

16 Nov 2012

People with Prader-Willi Syndrome may have impaired autonomic nervous system

An Australian study reveals that people with the rare genetic disorder known as Prader-Willi Syndrome may have an impaired autonomic nervous system. This discovery opens up a new way of looking at the insatiable appetite experienced by all sufferers, as well as their very high risk of cardiovascular disease.

16 Nov 2012

Pachytene piRNAs play an essential role in protecting post-meiotic germ cells

Passing one's genes on to the next generation is a mark of evolutionary success. So it makes sense that the body would work to ensure that the genes the next generation inherits are exact replicas of the originals.

16 Nov 2012

Study looks at health outcomes of kidney transplant recipients with low donor-specific antibodies

Kidney transplant recipients who have even very low levels of preformed antibodies directed against a donated kidney have a significantly increased risk of organ rejection and kidney failure, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

16 Nov 2012

Maternal vitamin C deficiency can have serious consequences for foetal brain

Maternal vitamin C deficiency during pregnancy can have serious consequences for the foetal brain. And once brain damage has occurred, it cannot be reversed by vitamin C supplements after birth. This is shown through new research at the University of Copenhagen just published in the scientific journal PLOS ONE.

16 Nov 2012

Tanshinones protect against sepsis: Study

Researchers at The Feinstein Institute for Medical Research have discovered that tanshinones, which come from the plant Danshen and are highly valued in Chinese traditional medicine, protect against the life-threatening condition sepsis. The findings are published in the December issue of Biochemical Pharmacology.

16 Nov 2012

Study finds specific way in which Salmonella counteract defense mechanisms of human cells

A new study by researchers at Imperial College London has identified a way in which Salmonella bacteria, which cause gastroenteritis and typhoid fever, counteract the defence mechanisms of human cells.

16 Nov 2012

Researchers discover unlikely recipe to kill antibiotic resistant bacteria

Washington State University researchers have found an unlikely recipe for antibiotic resistant bacteria: Mix cow dung and soil, and add urine infused with metabolized antibiotic. The urine will kill off normal E. coli in the dung-soil mixture. But antibiotic-resistant E. coli will survive in the soil to recolonize in a cow's gut through pasture, forage or bedding.

16 Nov 2012

Genetic link between rheumatoid arthritis and the X chromosome

Researchers have pieced together new genetic clues to the arthritis puzzle in a study that brings potential treatments closer to reality and could also provide insights into why more women than men succumb to the disabling condition.

15 Nov 2012

Researchers identify broad patterns of gene activity that correspond to aggression

With a mate and a nest to protect, the male threespined stickleback is a fierce fish, chasing and biting other males until they go away.

15 Nov 2012

Medical Science News

New insights into how MSCs ‘traffic’ from the circulation into tissues

New pathway appears to play a major role in information processing in the brain

Oxytocin regulates social distance between women and men

Shear thinning hydrogels hold promise in treating many diseases, including cancer

GigaScience announces publication of whole-genome sequencing and analysis of Wuzhishan Pig

D737 compound restores motor function and longevity in fruit flies with Alzheimer's

Researchers make groundbreaking discovery into optimization of light sources to human vision

Study finds mechanism that mediates inhibition of critical breathing muscles during REM sleep

AGT2R gene variant may predispose women to pre-eclampsia

Low levels of omega-3 may be behind postpartum depression

Freestyle rapping increases brain activity in the medial prefrontal cortex

People with Prader-Willi Syndrome may have impaired autonomic nervous system

Pachytene piRNAs play an essential role in protecting post-meiotic germ cells

Study looks at health outcomes of kidney transplant recipients with low donor-specific antibodies

Maternal vitamin C deficiency can have serious consequences for foetal brain

Tanshinones protect against sepsis: Study

Study finds specific way in which Salmonella counteract defense mechanisms of human cells

Researchers discover unlikely recipe to kill antibiotic resistant bacteria

Genetic link between rheumatoid arthritis and the X chromosome

Researchers identify broad patterns of gene activity that correspond to aggression

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