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Scientists obtain detailed molecular structure of member of Tet family of enzymes

Scientists have obtained the first detailed molecular structure of a member of the Tet family of enzymes.

28 Dec 2013

Combination of NGF microspheres and chitosan conduits exhibit better effects in repairing facial nerve injury

The chitosan molecule can promote nerve cell adherence and growth along the surface of the material. It can enhance the adherence and influx of Schwann cells, thus encouraging the growth of axons.

28 Dec 2013

Protein responsible for excretion of copper in body cells utilizes unique transport mechanism

We are fundamentally dependent on the presence of copper in the cells of the body. Copper is actually part of the body's energy conversion and protective mechanisms against oxygen radicals, as well as part of the immune system, and it also has great importance for the formation of e.g. hormones and neurotransmitters.

28 Dec 2013

Cancer immunotherapy named 2013 Breakthrough of the Year by journal Science

Detect. Destroy. Remember. The mantra of the immune system's relentless campaign against infectious invaders and the body's own abnormal cells finally is applying to cancer in meaningful ways.

28 Dec 2013

Unprecedented, atom-scale simulation of G protein-coupled receptor site's transformation

Roughly 40 percent of all medications act on cells' G protein-coupled receptors (GPCRs). One of these receptors, beta 2 adrenergic receptor site (B2AR), naturally transforms between two base configurations; knowing the precise location of each of approximately 4,000 atoms is crucial for ensuring a snug fit between it and the drug.

28 Dec 2013

Rho-associated protein kinase regulates hippocampal neurite growth, microtubule formation

Rho-associated protein kinase is an essential regulator of cytoskeletal dynamics during the process of neurite extension. However, whether Rho kinase regulates microtubule remodeling or the distribution of adhesive proteins to mediate neurite outgrowth remains unclear.

28 Dec 2013

Study shows beneficial effects of normobaric oxygen on cerebral ischemic injury

Normobaric oxygen has the rapid and non-invasive characteristics and may have therapeutic effects on ischemic/hypoxic disease.

28 Dec 2013

Stroke rehabilitation researchers report improvement in spatial neglect with prism adaptation therapy

Stroke rehabilitation researchers report improvement in spatial neglect with prism adaptation therapy. This new study supports behavioral classification of patients with spatial neglect as a valuable tool for assigning targeted, effective early rehabilitation.

27 Dec 2013

Researchers explore ways to overcome transplant rejection

Given that 10.5 % of patients who receive a transplant reject the new organ, researchers at the Center of Research and Advanced Studies of the National Polytechnic Institute (Cinvestav) are working in the design of a tool capable of preventing this problem.

27 Dec 2013

MitoQ antioxidant reverses MS-like disease in animal

Researchers at Oregon Health & Science University have discovered that an antioxidant designed more than a dozen years ago to fight damage within human cells significantly helps symptoms in mice that have a multiple sclerosis-like disease.

27 Dec 2013

Researchers study health consequences of RTE proliferation that occurs in aging tissues

The genomes of organisms from humans to corn are replete with "parasitic" strands of DNA that, when not suppressed, copy themselves and spread throughout the genome, potentially affecting health. Earlier this year Brown University researchers found that these "retrotransposable elements" were increasingly able to break free of the genome's control in cultures of human cells.

27 Dec 2013

Research: Neuropeptides may serve as index for evaluating early peripheral nerve injury

Substance P and calcitonin gene-related peptide are the main neuropeptides in peripheral nerve ganglia, which can anterogradely transmit nociceptive information to the central nervous system.

27 Dec 2013

Stem cell-based gene therapy shows long-term outcomes for treatment of genetic skin diseases

Stem cell-based gene therapy holds promise for the treatment of devastating genetic skin diseases, but the long-term clinical outcomes of this approach have been unclear.

27 Dec 2013

Experts to share insights on the integration of science, psychotherapy and spirituality

Neuroscience is the new buzzword in the world of psychotherapy, yet distinguishing between true innovation and mere speculation can be difficult. In a new program at the 2014 iaedp Symposium in St. Petersburg, Florida (February 26-March 2), keynote speakers, Carolyn Costin, MFt, MA, MEd, CEDS and Joan Borysenko, PhD, will share their insights on the integration of science, psychotherapy and spirituality.

27 Dec 2013

Magnetic nanoparticles-based method uses saliva to screen DNA polymorphism in stroke patients

C677T polymorphism in the methylenetetrahydrofolate reductase (MTHFR) gene is a risk factor for stroke. Studies have report a higher C677T homozygosity frequency in Chinese than in Europeans. Usually, the detection of genetic diseases is rather complicated on a large scale owing to the invasive sampling and a cumbersome DNA extraction process.

27 Dec 2013

Research shows that human brains stumble on even the simplest rule-based calculations

Even scientists are fond of thinking of the human brain as a computer, following sets of rules to communicate, make decisions and find a meal.

24 Dec 2013

Hypoxic preconditioning has protective effects against acute cerebral infarction

Hypoxic preconditioning has been shown to have protective effects against acute cerebral infarction. To investigate the protective mechanisms of hypoxic preconditioning in relation to its effects on angiogenesis, Prof. Xunming Ji and team from Xuanwu Hospital, Capital Medical University in China induced a photochemical model of cerebral infarction in an inbred line of mice (BALB/c) which were exposed to hypoxic preconditioning prior to model establishment.

24 Dec 2013

Cell transplantation, gene therapy combination to open new therapeutic avenues for Alzheimer's disease

In a recent study published in the Neural Regeneration Research (Vol. 8, No. 33, 2013), Prof. Feng Li and team from Zhongshan School of Medicine, Sun Yat-sen University in China, synthesized a 19-nt oligonucleotide targeting BACE1, the key enzyme in amyloid beta protein (Aβ) production, and introduced it into the pSilenCircle vector to construct a short hairpin (shRNA) expression plasmid against the BACE1 gene.

24 Dec 2013

Study explores how genetic sequencing can help fight new strains of flu

Published in the Journal Proceedings of the National Academy of Sciences, senior author, Associate Professor Katherine Kedzierska from the Department of Microbiology and Immunology said that being able to predict which patients will be more susceptible to the emerging influenza strain, will allow clinicians to better manage an early intervention strategy.

24 Dec 2013

Fluidigm announces universal sample prep workflow for single-cell DNA sequencing

Fluidigm Corporation today announced a universal sample prep workflow for single-cell DNA sequencing that runs on its C1TM Single-Cell Auto Prep System. This workflow streamlines targeted, whole exome and whole genome sequencing in heterogeneous cell populations and enables researchers to discover and screen somatic mutations, such as SNP, small indels, and translocations.

24 Dec 2013

Medical Science News

Scientists obtain detailed molecular structure of member of Tet family of enzymes

Combination of NGF microspheres and chitosan conduits exhibit better effects in repairing facial nerve injury

Protein responsible for excretion of copper in body cells utilizes unique transport mechanism

Cancer immunotherapy named 2013 Breakthrough of the Year by journal Science

Unprecedented, atom-scale simulation of G protein-coupled receptor site's transformation

Rho-associated protein kinase regulates hippocampal neurite growth, microtubule formation

Study shows beneficial effects of normobaric oxygen on cerebral ischemic injury

Stroke rehabilitation researchers report improvement in spatial neglect with prism adaptation therapy

Researchers explore ways to overcome transplant rejection

MitoQ antioxidant reverses MS-like disease in animal

Researchers study health consequences of RTE proliferation that occurs in aging tissues

Research: Neuropeptides may serve as index for evaluating early peripheral nerve injury

Stem cell-based gene therapy shows long-term outcomes for treatment of genetic skin diseases

Experts to share insights on the integration of science, psychotherapy and spirituality

Magnetic nanoparticles-based method uses saliva to screen DNA polymorphism in stroke patients

Research shows that human brains stumble on even the simplest rule-based calculations

Hypoxic preconditioning has protective effects against acute cerebral infarction

Cell transplantation, gene therapy combination to open new therapeutic avenues for Alzheimer's disease

Study explores how genetic sequencing can help fight new strains of flu

Fluidigm announces universal sample prep workflow for single-cell DNA sequencing

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?

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