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MCCIR scientists use video imaging to investigate effectiveness of rituximab in killing cancerous B cells

Scientists from the Manchester Collaborative Centre for Inflammation Research have discovered why a particular cancer drug is so effective at killing cells.

From The University of Manchester 25 Apr 2013

Novel approach using Listeria bacteria shows promise against metastatic pancreatic cancer

Researchers at Albert Einstein College of Medicine of Yeshiva University have developed a therapy for pancreatic cancer that uses Listeria bacteria to selectively infect tumor cells and deliver radioisotopes into them.

25 Apr 2013

Higher TMAO blood levels linked to increased risk of heart disease

A microbial byproduct of intestinal bacteria contributes to heart disease and serves as an accurate screening tool for predicting future risks of heart attack, stroke and death in persons not otherwise identified by traditional risk factors and blood tests, according to Cleveland Clinic research published today in The New England Journal of Medicine.

25 Apr 2013

Astrocytes more effective in promoting recovery after brain injury

The production of a certain kind of brain cell that had been considered an impediment to healing may actually be needed to staunch bleeding and promote repair after a stroke or head trauma, researchers at Duke Medicine report.

25 Apr 2013

Sirolimus effective in treating children with Pretzel syndrome, new study reports

With a better understanding of underlying mechanisms that cause a rare neurodevelopmental disorder in the Old Order Mennonite population, referred to as Pretzel syndrome, a new study reports that five children were successfully treated with a drug that modifies the disease process, minimizing seizures and improving receptive language.

25 Apr 2013

Individuals with MEN1 are at increased risk of developing neuroendocrine tumors

A mutation in a protein called menin causes a hereditary cancer syndrome called MEN1 (multiple endocrine neoplasia type 1).

25 Apr 2013

Personalized PSA testing using genetic variants reduces unnecessary prostate biopsies

With the help of genetics, prostate specific antigen screenings may become more accurate and reduce the number of unnecessary prostate biopsies, according to a new study from Northwestern Medicine.

25 Apr 2013

Hospital for Special Surgery receives grant for new genomics center to study autoimmune diseases

Hospital for Special Surgery in New York City has received a $5.6 million grant from The Tow Foundation to establish the Hospital for Special Surgery Genomics Center.

25 Apr 2013

Cultivation of legumes helps farmers add natural nitrogen to agricultural fields

The overuse of nitrogen fertilizers in agriculture can wreak havoc on waterways, health and the environment.

25 Apr 2013

Vesicular stomatitis virus spares non-cancerous cells and kills melanoma cells

Researchers from Yale University School of Medicine have demonstrated that vesicular stomatitis virus (VSV) is highly competent at finding, infecting, and killing human melanoma cells, both in vitro and in animal models, while having little propensity to infect non-cancerous cells.

25 Apr 2013

Individual hydroxymethylcytosine molecules in DNA detected by new method involving chemical modification and nanopore analysis

Changes in the bases that make up DNA act as markers, telling a cell which genes it should read and which it shouldn’t. In the journal Angewandte Chemie, a British team has now introduced a new method that makes it possible to enrich the rare gene segments that contain the modified base hydroxymethylcytosine and to identify individual hydroxymethylcytosine molecules in DNA. Such modifications are associated with autoimmune diseases and cancer.

24 Apr 2013

New research ties mushrooms to potential health outcomes

New research published as abstracts in The FASEB Journal and presented at Experimental Biology 2013 ties mushrooms to potential health outcomes - demonstrating that mushrooms provide more to a dish than just flavor.

24 Apr 2013

Advaita selected to participate in Michigan I-Corps program starting May 2013

Advaita, a Plymouth, MI biotechnology startup company spun out from Wayne State University, is one of 25 companies selected to participate in the new Michigan I-Corps program starting May 2013.

24 Apr 2013

Tissue engineering combined with gene therapy can manage repair of defective articular cartilage

Researchers at Micro Orthopaedics, Zhongnan Hospital of Wuhan University, led by Dr. Ai-xi Yu, have suggested that articular cartilage defects can be repaired by a novel thermo-sensitive injectable hydrogel engineered with gene modified bone marrow mesenchymal stromal cells.

24 Apr 2013

Researchers decode toggle switch that can stimulate fat burning

For a long time, scientists have dreamt of converting undesirable white fat cells into brown fat cells and thus simply have excess pounds melt away. Researchers at the University of Bonn have now gotten a step closer to this goal: They decoded a "toggle switch" in mice which can significantly stimulate fat burning.

24 Apr 2013

Nanogels to attack lupus: an interview with Dr Look and Dr Fahmy, Yale University

Nanogels are synthetic particles that can be used for drug delivery. They are approximately 100 nm to 200 nm in diameter, and are made from safe, biocompatible materials: a gel-like interior and a lipid exterior.

24 Apr 2013

Transformative technologies highlighted in current issue of Technology and Innovation

Improving brain function is one of the topics explored in the latest issue of Technology and Innovation - Proceedings of the National Academy of Inventors.

24 Apr 2013

Research project to identify mechanisms underlying effects of cancer drug interferon-α

The immune system plays a decisive role in the fight against tumor cells. However, when tumor cells themselves prevent activation of the immune system, the immune system fails to destroy cancer cells.

24 Apr 2013

Study identifies gene variants associated with histological features of NAFLD

More patients could be diagnosed earlier with non-alcoholic fatty liver disease after a cohort study presented at the International Liver Congress 2013 identified variants within four genes significantly associated with the histological features of the disease.

24 Apr 2013

Study identifies malaria parasite protein as potential new target for drug treatment to prevent malaria

Scientists have discovered how a protein within the malaria parasite is essential to its survival as it develops inside a mosquito. They believe their findings identify this protein as a potential new target for drug treatments to prevent malaria being passed to humans.

24 Apr 2013

Medical Science News

MCCIR scientists use video imaging to investigate effectiveness of rituximab in killing cancerous B cells

Novel approach using Listeria bacteria shows promise against metastatic pancreatic cancer

Higher TMAO blood levels linked to increased risk of heart disease

Astrocytes more effective in promoting recovery after brain injury

Sirolimus effective in treating children with Pretzel syndrome, new study reports

Individuals with MEN1 are at increased risk of developing neuroendocrine tumors

Personalized PSA testing using genetic variants reduces unnecessary prostate biopsies

Hospital for Special Surgery receives grant for new genomics center to study autoimmune diseases

Cultivation of legumes helps farmers add natural nitrogen to agricultural fields

Vesicular stomatitis virus spares non-cancerous cells and kills melanoma cells

Individual hydroxymethylcytosine molecules in DNA detected by new method involving chemical modification and nanopore analysis

New research ties mushrooms to potential health outcomes

Advaita selected to participate in Michigan I-Corps program starting May 2013

Tissue engineering combined with gene therapy can manage repair of defective articular cartilage

Researchers decode toggle switch that can stimulate fat burning

Nanogels to attack lupus: an interview with Dr Look and Dr Fahmy, Yale University

Transformative technologies highlighted in current issue of Technology and Innovation

Research project to identify mechanisms underlying effects of cancer drug interferon-α

Study identifies gene variants associated with histological features of NAFLD

Study identifies malaria parasite protein as potential new target for drug treatment to prevent malaria

Edoardo Fabini

Reducing polypharmacy through innovative drug formulation technologies

How innovation in dried blood spot testing is transforming neurological disease monitoring

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