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Scientists find that mice develop age-related progressive motor symptoms of Parkinson's disease

The presence of Lewy bodies in nerve cells, formed by intracellular deposits of the protein α-synuclein, is a characteristic pathologic feature of Parkinson's Disease (PD). In the quest for an animal model of PD that mimics motor and non-motor symptoms of human PD, scientists have developed strains of mice that overexpress α-synuclein.

10 Jun 2013

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

A drug used to control Type II diabetes can help repair the spinal cords of mice suffering from the inherited disease adrenoleukodystrophy which, untreated, leads eventually to a paralysis, a vegetative state and death.

10 Jun 2013

Blood vessels within sensory area of mammalian brain loop connect in unexpected ways, new map reveals

Blood vessels within a sensory area of the mammalian brain loop and connect in unexpected ways, a new map has revealed.

10 Jun 2013

New non-invasive test measures methylation of SDC2 gene, detects 87% of colorectal cancer

The average 5-year survival for colorectal cancer (CRC) is less than 10% if metastasis occurs, but can reach 90% if detected early. A new non-invasive test has been developed that measures methylation of the SDC2 gene in tissues and blood sera.

10 Jun 2013

Common antidepressant medications may impair a form of learning, new report suggests

An interesting new report of animal research published in Biological Psychiatry suggests that common antidepressant medications may impair a form of learning that is important clinically.

10 Jun 2013

Whitehead Institute researchers identify drug target for anemia

Researchers at Whitehead Institute have identified a protein that is the target of glucocorticoids, the drugs that are used to increase red blood cell production in patients with certain types of anemia, including those resulting from trauma, sepsis, malaria, kidney dialysis, and chemotherapy.

10 Jun 2013

Viewpoints: Will 'rate shock' grow?; Krugman says GOP spite is driving opposition to Medicaid expansion; Determining who owns genes

Any plausible health care reform, the various conservative alternatives to Obamacare included, would necessarily have losers as well as winners, and as far as potential losers go single young men with above-average incomes are not precisely the country's most disadvantaged demographic. If you think the current system is flawless, then I suppose any rate increase anywhere is a strike against health care reform.

10 Jun 2013

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Novel abnormalities in the FGFR gene, called FGFR fusions, were identified in a spectrum of cancers, and preliminary results with cancer cells harboring FGFR fusions suggested that some patients with these cancers may benefit from treatment with FGFR inhibitor drugs, according to data published in Cancer Discovery, a journal of the American Association for Cancer Research.

10 Jun 2013

Second-annual SINAInnovations conference to highlight power of Team Science

Leaders in health care, technology, design, the military and the arts will gather at The Mount Sinai Medical Center for the second-annual SINAInnovations conference on November 18 and 19, 2013.

10 Jun 2013

Optogenetics: A promising technique for treatment of obsessive-compulsive disorders

By applying light stimulation to highly specific neurons in the brain, the researchers managed to re-establish normal behaviour in mice that had beforehand presented pathological repetitive behaviour similar to that observed in human patients suffering from obsessive-compulsive disorders.

10 Jun 2013

Genetic testing for cancer-causing mutations in affected families is very low, study finds

A new study of the use of genetic testing for cancer-causing mutations in affected families in France has found that its take-up is very low.

10 Jun 2013

Data emphasise need for comprehensive analysis of mtDNA in mitochondrial disease patients

French scientists have discovered that supposedly rare mutations in the mitochondria, the 'power plants' of human cells responsible for creating energy, account for more than 7% of patients with a mitochondrial disease manifesting itself as a respiratory deficiency.

10 Jun 2013

Scientists discover how Arc protein helps translate learning into memory

Scientists at the Gladstone Institutes have deciphered how a protein called Arc regulates the activity of neurons-providing much-needed clues into the brain's ability to form long-lasting memories. These findings, reported today in Nature Neuroscience, also offer newfound understanding as to what goes on at the molecular level when this process becomes disrupted.

10 Jun 2013

Essential fatty acid found in vegetable oils does not promote inflammation in humans, scientists find

A typical American consumes approximately 3 or more tablespoons of vegetable oil each day. Vegetable oils, like those from soy, corn and canola, are a significant source of calories and are rich in linoleic acid, which is an essential nutrient.

10 Jun 2013

McGill researchers use computer simulations to show how immune cells identify foreign antigens

How do immune cells manage to sort through vast numbers of similar-looking proteins within the body to detect foreign invaders and fight infections?

10 Jun 2013

USC scientists unlock mystery of why new cases of Noonan Syndrome are so common

Scientists at USC have unlocked the mystery of why new cases of the genetic disease Noonan Syndrome are so common: a mutation that causes the disease disproportionately increases a normal father's production of sperm carrying the disease trait.

10 Jun 2013

Researchers discover potential target for cancer-fighting drugs

As tumors grow, their centers are squeezed of oxygen. And so tumors must flip specific genetic switches to survive in these hypoxic environments.

10 Jun 2013

Study sheds light on origin of wide range of brain disorders

Researchers at Weill Cornell Medical College have uncovered a mechanism that guides the exquisite wiring of neural circuits in a developing brain -- gaining unprecedented insight into the faulty circuits that may lead to brain disorders ranging from autism to mental retardation.

10 Jun 2013

Researchers find new way to repair genetic defects in the skin cells of epidermolysis bullosa patients

A research team led by pediatric blood and marrow transplantation experts Mark Osborn, Ph.D. and Jakub Tolar, M.D., Ph.D. from the Masonic Cancer Center, University of Minnesota, have discovered a remarkable new way to repair genetic defects in the skin cells of patients with the skin disease epidermolysis bullosa.

10 Jun 2013

Researchers find way to differentiate iPSCs into mature human neurons in the brain

Difficult-to-study diseases such as Alzheimer's, schizophrenia, and autism now can be probed more safely and effectively thanks to an innovative new method for obtaining mature brain cells called neurons from reprogrammed skin cells. According to Gong Chen, the Verne M. Willaman Chair in Life Sciences and professor of biology at Penn State University and the leader of the research team, "the most exciting part of this research is that it offers the promise of direct disease modeling, allowing for the creation, in a Petri dish, of mature human neurons that behave a lot like neurons that grow naturally in the human brain."

10 Jun 2013

Medical Science News

Scientists find that mice develop age-related progressive motor symptoms of Parkinson's disease

Drug used to control Type II diabetes can help repair spinal cords of mice suffering from inherited disease

Blood vessels within sensory area of mammalian brain loop connect in unexpected ways, new map reveals

New non-invasive test measures methylation of SDC2 gene, detects 87% of colorectal cancer

Common antidepressant medications may impair a form of learning, new report suggests

Whitehead Institute researchers identify drug target for anemia

Viewpoints: Will 'rate shock' grow?; Krugman says GOP spite is driving opposition to Medicaid expansion; Determining who owns genes

Novel abnormalities in FGFR gene identified in a spectrum of cancers

Second-annual SINAInnovations conference to highlight power of Team Science

Optogenetics: A promising technique for treatment of obsessive-compulsive disorders

Genetic testing for cancer-causing mutations in affected families is very low, study finds

Data emphasise need for comprehensive analysis of mtDNA in mitochondrial disease patients

Scientists discover how Arc protein helps translate learning into memory

Essential fatty acid found in vegetable oils does not promote inflammation in humans, scientists find

McGill researchers use computer simulations to show how immune cells identify foreign antigens

USC scientists unlock mystery of why new cases of Noonan Syndrome are so common

Researchers discover potential target for cancer-fighting drugs

Study sheds light on origin of wide range of brain disorders

Researchers find new way to repair genetic defects in the skin cells of epidermolysis bullosa patients

Researchers find way to differentiate iPSCs into mature human neurons in the brain

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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