Medical Science News

RSS

Hypothalamic ECM remodeling drives insulin resistance, contributing to obesity and diabetes

Researchers have discovered that remodeling of extracellular matrix (ECM) in the hypothalamus, specifically around AgRP neurons, drives insulin resistance and metabolic disease. Disrupting this ECM buildup improves insulin sensitivity and may be a promising treatment for obesity and diabetes.

19 Sep 2024

Do long genes hold the key to understanding the genetic underpinnings of aging?

Review highlights the growing evidence that aging is linked to reduced expression of long genes, offering insights into potential anti-aging therapies based on gene length.

19 Sep 2024

Study reveals MYC gene's role in prostate cancer initiation and progression

By tracking the changes in prostate cancer cells over time, researchers at the Johns Hopkins Kimmel Cancer Center have found that activation of the MYC gene - a well-known cancer-causing gene - sets off a cascade of events that leads to both initiation and progression of the disease.

19 Sep 2024

Researchers identify bacterial strains to combat antibiotic-resistant gut infections

Antibiotic-resistant bacterial infections often occur in patients with chronic inflammatory intestinal conditions, such as inflammatory bowel disease, and in patients who have taken antibiotics for a long time.

19 Sep 2024

Immune proteins in tooth enamel provide clues about ancient human health

A new way of looking at tooth enamel could give scientists a path to deeper understanding of the health of human populations, from the ancient to the modern.

19 Sep 2024

Global fight against antimicrobial resistance sees surge in deaths among older adults

Comprehensive study estimates the global antimicrobial resistance (AMR) burden from 1990 to 2021, identifying significant age and regional disparities. It highlights future AMR death projections and underscores the importance of prevention and new antibiotic development.

19 Sep 2024

Cellular sludge around hunger neurons linked to worsening diabetes and obesity

Investigating ECM changes in the hypothalamus reveals mechanisms behind insulin resistance, offering insights into obesity and metabolic disease treatment.

19 Sep 2024

Study reveals impact of human breast milk on infant microbiome and respiratory health

Human breast milk regulates a baby's mix of microbes, or microbiome, during the infant's first year of life. This in turn lowers the child's risk of developing asthma, a new study shows.

19 Sep 2024

New model reveals mechanisms of lung injury from mechanical ventilation

For the first time, scientists are able to directly compare the different kinds of injury that mechanical ventilation causes to cells in the lungs.

19 Sep 2024

Analyzing the connection between lifelong activity and longevity in aging research

A new research perspective was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 17 on September 9, 2024, entitled, "Longitudinal activity monitoring and lifespan: quantifying the interface."

19 Sep 2024

Study reveals links between bodily rhythms and visual perception

A study funded by the SNSF highlights previously unknown links between the body and the brain. The findings of this research carried out at the University of Fribourg show how our bodily rhythms affect our visual perception.

19 Sep 2024

Hypoxia's hidden role in boosting anti-cancer immunity

In the complex landscape of cancer, tumors create their own microenvironment, often marked by low oxygen levels, a condition known as hypoxia.

19 Sep 2024

Cardiovascular disease pathways associated with psoriasis, but not other immune-mediated diseases

A genetic connection between cardiovascular disease and psoriasis highlights shared inflammatory pathways, emphasizing the need for cardiovascular monitoring.

19 Sep 2024

Study highlights disparities in stroke burden across regions

Although stroke is highly preventable and treatable, there has been a rapid rise in the global stroke burden between 1990 and 2021, due to both population growth and the rise of aging populations worldwide, as well as a substantial increase in people's exposure to environmental and behavioral risk factors.

19 Sep 2024

Study finds thousands of food-contact chemicals in humans, raising safety concerns

A recent study reveals that 25% of known food-contact chemicals (FCCs) are present in humans, with significant gaps in hazard data for many chemicals, highlighting potential health risks.

19 Sep 2024

Study highlights the importance of placental evaluation in pregnancy outcomes

In an opinion article publishing September 18 in the Cell Press journal Trends in Molecular Medicine, physician-scientists argue that with most placentas discarded after birth, placental pathology is underutilized clinically, should be a routine part of obstetric and neonatal care, and also deserves more research attention.

19 Sep 2024

New kidney chip offers breakthrough for drug development and personalized medicine

Developing advanced drug screening tools is crucial for the advancement of personalized medicine and the creation of more effective treatments. One organ receiving particular attention in this area is the kidney.

19 Sep 2024

Researchers uncover receptor that dampens sensory input

Signals in our brain are not always processed in the same way: Certain receptors modulate these mechanisms, influencing our mood, perception, and behavior in various ways. One of these is the 5-HT2A receptor, which has a recently discovered unique characteristic.

18 Sep 2024

New biomarkers offer hope for early detection and prevention of Alzheimer's

The failure to diagnose Alzheimer's disease, the most common form of dementia in the elderly, at an early stage of molecular pathology is considered a major reason why treatments fail in clinical trials. Previous research to molecularly diagnose Alzheimer's disease yielded "A/T/N" central biomarkers based on the measurements of proteins, β-amyloid ("A") and tau ("T"), and "N" encompassing neurodegeneration. A/T/N can be measured in brain tissue, by in vivo brain imaging techniques, and by analysis of cerebrospinal fluid and plasma.

18 Sep 2024

Leptin variations may influence brain health and dementia development

New research is more closely linking obesity to dementia. Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults, according to a study by The University of Texas Health Science Center at San Antonio (UT Health San Antonio).

18 Sep 2024

Medical Science News

Hypothalamic ECM remodeling drives insulin resistance, contributing to obesity and diabetes

Do long genes hold the key to understanding the genetic underpinnings of aging?

Study reveals MYC gene's role in prostate cancer initiation and progression

Researchers identify bacterial strains to combat antibiotic-resistant gut infections

Immune proteins in tooth enamel provide clues about ancient human health

Global fight against antimicrobial resistance sees surge in deaths among older adults

Cellular sludge around hunger neurons linked to worsening diabetes and obesity

Study reveals impact of human breast milk on infant microbiome and respiratory health

New model reveals mechanisms of lung injury from mechanical ventilation

Analyzing the connection between lifelong activity and longevity in aging research

Study reveals links between bodily rhythms and visual perception

Hypoxia's hidden role in boosting anti-cancer immunity

Cardiovascular disease pathways associated with psoriasis, but not other immune-mediated diseases

Study highlights disparities in stroke burden across regions

Study finds thousands of food-contact chemicals in humans, raising safety concerns

Study highlights the importance of placental evaluation in pregnancy outcomes

New kidney chip offers breakthrough for drug development and personalized medicine

Researchers uncover receptor that dampens sensory input

New biomarkers offer hope for early detection and prevention of Alzheimer's

Leptin variations may influence brain health and dementia development

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

Latest News