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Leptin could offer alternative to insulin for managing type 1 diabetes complication

More than a decade ago, researchers found that an acute complication of type 1 diabetes, diabetic ketoacidosis (DKA), can be resolved with the hormone leptin, even in the absence of insulin.

4 Aug 2025

New brainwave marker identified for Alzheimer’s detection

Using a custom-built tool to analyze electrical activity from neurons, researchers at Brown University have identified a brain-based biomarker that could be used to predict whether mild cognitive impairment will develop into Alzheimer's disease.

4 Aug 2025

New analgesic shows promise as opioid alternative

Opioids like morphine are widely used in medical practice due to their powerful pain-relieving effects. However, they carry the risk of serious adverse effects such as respiratory depression and drug dependence.

4 Aug 2025

Sleep strengthens motor learning through targeted brain rhythms

When faced with difficult tasks, sometimes people hit a mental wall and make the decision to "sleep on it." Returning to the task after sleeping, they often perform better. Why? Rhythmic brain activity during sleep transforms task-related information into stronger, longer-term memory.

4 Aug 2025

Targeted botox delivery shows promise for treating jaw disorder

Temporomandibular disorder (TMD) limits jaw function and is so painful that it lessens the quality of life.

4 Aug 2025

Mouth and gut microbes talk to each other - here’s why it matters for disease

Researchers reviewed nearly 250 studies to uncover how the oral and gut microbiomes communicate through multiple pathways, influencing the risk of diseases such as IBD, colorectal cancer, and cardiovascular disorders. The review highlights that maintaining oral health and dietary habits is crucial for overall systemic wellbeing.

4 Aug 2025

Scientists reveal how rare gene mutations drive schizophrenia risk

Researchers analyzed the largest exome-sequencing dataset to date and identified new rare coding variants and genes linked to schizophrenia risk. The study highlights converging genetic pathways, implicating chromatin organization and GABAergic signaling in schizophrenia neurobiology.

4 Aug 2025

Impulsivity shapes diet and gut bacteria in healthy adults, study finds

Impulsivity in healthy adults is linked to unhealthy dietary choices, such as higher intake of alcohol and sugary drinks and lower fiber consumption. These dietary behaviors, in turn, are associated with changes in specific gut bacterial genera, highlighting an indirect pathway between personality traits and the gut microbiome.

4 Aug 2025

HIV trial points to semaglutide as a new anti-aging contender

Once-weekly semaglutide significantly slowed epigenetic aging in adults with HIV-associated lipohypertrophy, as measured by multiple DNA methylation clocks in a randomized controlled trial. These exploratory findings suggest GLP-1 receptor agonists could impact biological aging but require further validation in broader populations.

4 Aug 2025

UCLA study shows stem cells can be reprogrammed to fight cancer

In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune system's most powerful cancer-killing agents.

4 Aug 2025

Weight loss doubles when eating minimally processed foods over ultra-processed alternatives

When given nutritionally matched diets, participants lost twice as much weight eating minimally processed foods compared to ultra-processed foods, suggesting that cutting down on processing could help to sustain a healthy weight long term, finds a new clinical trial led by researchers at UCL and UCLH.

4 Aug 2025

Understanding the importance of B vitamins for health

Eight different vitamins make up the B complex, and they all play crucial roles in the body, such as producing energy, keeping our nervous system healthy, and supporting cell development.

4 Aug 2025

Psychedelic and non-hallucinogenic drugs promote neuroplasticity through shared pathways

Understanding exactly how psychedelics promote new connections in the brain is critical to developing targeted, non-hallucinogenic therapeutics that can treat neurodegenerative and neuropsychiatric diseases.

4 Aug 2025

New Swiss study probes lingering fatigue after Legionnaires' disease

Researchers in Switzerland launched the LongLEGIO study to compare the long-term health impacts of Legionnaires’ disease and other bacterial pneumonias. Baseline data reveal key differences in comorbidities and quality of life between the groups, with follow-up underway.

4 Aug 2025

Can your diet and health change your breast milk? Review uncovers the key maternal and birth factors

This review highlights how maternal, obstetrical, and neonatal factors influence the energy and macronutrient content of breast milk. The findings underscore significant variability in milk composition, with implications for tailored nutritional support in early life.

3 Aug 2025

Metformin’s blood sugar control starts in the brain, not just the liver, study finds

Low, clinically relevant doses of metformin lower blood glucose by inhibiting the Rap1 protein in specific neurons of the hypothalamus, revealing a brain-first mechanism. This action is essential for metformin’s effect at therapeutic doses and highlights new directions for diabetes treatment.

3 Aug 2025

AI spots hidden diabetes risk even when test results look normal

Researchers used continuous glucose monitoring and multimodal data from over 3,000 people to reveal hidden patterns in glucose spikes across normoglycemia, prediabetes, and type 2 diabetes. Their AI-driven model exposed high individual variability and offers a personalized path for early detection and prevention of diabetes.

3 Aug 2025

Immune molecule found to play a key role in regulating inflammation in rheumatoid arthritis

Researchers at Kyoto University have discovered that an immune molecule found only in primates, called IGFL2, plays a key role in regulating inflammation in rheumatoid arthritis (RA).

1 Aug 2025

Mapping the brain’s serotonin switch could lead to better antidepressants

In a discovery that could guide the development of next-generation antidepressants and antipsychotic medications, researchers at the Icahn School of Medicine at Mount Sinai have developed new insights into how a critical brain receptor works at the molecular level and why that matters for mental health treatments.

1 Aug 2025

Key protein found to guide melanoma cells during spread

Researchers have discovered a protein which is critical for steering melanoma cancer cells as they spread throughout the body.

1 Aug 2025

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Medical Science News

Leptin could offer alternative to insulin for managing type 1 diabetes complication

New brainwave marker identified for Alzheimer’s detection

New analgesic shows promise as opioid alternative

Sleep strengthens motor learning through targeted brain rhythms

Targeted botox delivery shows promise for treating jaw disorder

Mouth and gut microbes talk to each other - here’s why it matters for disease

Scientists reveal how rare gene mutations drive schizophrenia risk

Impulsivity shapes diet and gut bacteria in healthy adults, study finds

HIV trial points to semaglutide as a new anti-aging contender

UCLA study shows stem cells can be reprogrammed to fight cancer

Weight loss doubles when eating minimally processed foods over ultra-processed alternatives

Understanding the importance of B vitamins for health

Psychedelic and non-hallucinogenic drugs promote neuroplasticity through shared pathways

New Swiss study probes lingering fatigue after Legionnaires' disease

Can your diet and health change your breast milk? Review uncovers the key maternal and birth factors

Metformin’s blood sugar control starts in the brain, not just the liver, study finds

AI spots hidden diabetes risk even when test results look normal

Immune molecule found to play a key role in regulating inflammation in rheumatoid arthritis

Mapping the brain’s serotonin switch could lead to better antidepressants

Key protein found to guide melanoma cells during spread

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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