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Discovery of key protein for burning fat may lead to obesity treatments

Obesity, which affects 650 million people worldwide, influences the development of cardiometabolic diseases and increases the risk of cancer.

13 Jan 2025

By 2060, 1 million U.S. adults are projected to develop dementia annually

The lifetime risk of dementia is 42%, with significant variations by race and sex, underscoring the importance of public health strategies for prevention.

13 Jan 2025

Short-chain fatty acids propionate and butyrate directly modify chromatin to regulate gene expression

Short-chain fatty acids influence gene regulation and chromatin accessibility, highlighting their role in colorectal cancer and normal cellular processes.

13 Jan 2025

Sleep loss triggers intrusive memories by disrupting REM sleep

Sleep deprivation affects the brain's memory control, with REM sleep essential for effective suppression of intrusive memories and cognitive function.

13 Jan 2025

Study finds certain H5N1 strains in cattle linked to milder human illness; other variants remain a concern

Study reveals that contemporary HPAI H5N1 viruses show reduced replication and immune activation in human lung organoids, potentially explaining milder disease in humans compared to historic strains.

13 Jan 2025

Mortality risks soar with ultra-processed foods - simple diet changes can help

Ultra-processed food consumption increases mortality risks, particularly from circulatory, digestive diseases, and Parkinson's, but substituting minimally processed foods can lower these risks.

12 Jan 2025

Being fit matters more than weight for long-term health, research shows

Cardiorespiratory fitness significantly reduces mortality risks regardless of BMI, highlighting fitness as a critical health determinant over weight loss strategies.

12 Jan 2025

Totally implantable cochlear implant promises a new era of hearing restoration

Scientists have developed a totally implantable cochlear implant that delivers hearing performance comparable to conventional devices while improving quality of life and eliminating the need for external components.

12 Jan 2025

Plant chemical discovered to prevent biofilm formation

If your teeth have ever felt fuzzy after skipping a brushing, you've encountered biofilm-a slimy bacterial layer that clings to surfaces. In medical settings, biofilms make infections harder to treat when they form protective shields for bacteria on devices like catheters and implants.

10 Jan 2025

New guidelines for correct use of biochemical indices of bone statuss published

The Joint International Osteoporosis Foundation (IOF) Working Group and the International Federation of Clinical Chemistry (IFCC) Committee on Bone Metabolism have published important updated guidelines for the correct use of biochemical indices of bone status.

10 Jan 2025

New software tool offers insights into 3D imaging of heart development

Researchers have developed a new software tool that provides unprecedented capabilities to see inside 3D images.

10 Jan 2025

Menarini Group signs licensing deal with Insilico for promising cancer treatment

The Menarini Group ("Menarini"), a leading international pharmaceutical and diagnostics company, and Stemline Therapeutics, Inc. ("Stemline"), a wholly-owned subsidiary of the Menarini Group focused on bringing transformational oncology treatments to cancer patients, and Insilico Medicine ("Insilico"), a clinical stage generative artificial intelligence (AI)-driven biotechnology company, today announced that the companies have entered into an exclusive licensing agreement granting Stemline the global rights to develop and commercialize a preclinical small molecule targeting high unmet needs in oncology.

10 Jan 2025

Scientists uncover evolution of ventral nerve cord in ecdysozoan animals

An international team of scientists has uncovered a fascinating piece of the evolutionary puzzle: how the ventral nerve cord, a key component of the central nervous system, evolved in ecdysozoan animals, a group that includes insects, nematodes, and priapulid worms.

10 Jan 2025

NIH grant supports study of copper's role in killing harmful bacteria

A researcher at the University of Arizona College of Medicine – Tucson received a $1.9 million grant from the National Institutes of Health to continue his research into uncovering the mysteries of copper – specifically, how it can be harnessed to kill harmful bacteria and other microorganisms.

10 Jan 2025

Red light exposure may help reduce risk of blood clots

Humans and mice exposed to long-wavelength red light had lower rates of blood clots that can cause heart attacks, lung damage and strokes, according to research led by University of Pittsburgh School of Medicine and UPMC surgeon-scientists and published today in the Journal of Thrombosis and Haemostasis.

10 Jan 2025

Biglycan and decorin play crucial roles in bone health

Bone tissue is a complex structure, consisting of mineralized collagen fibers and a variety of non-collagenous proteins, including proteoglycans such as biglycan and decorin.

10 Jan 2025

Eating more fiber supports growth of good bacteria and protects against gut infections

The group of bacteria called Enterobacteriaceae, including Klebsiella pneumoniae, Shigella, E.coli and others, is present at low levels as part of a healthy human gut microbiome.

10 Jan 2025

Self-destructing vaccine offers safer TB protection in monkeys

A self-destructing vaccine administered intravenously provides additional safety and protection against tuberculosis (TB) in macaque monkeys, suggests new University of Pittsburgh research published today in Nature Microbiology.

10 Jan 2025

T cells can completely prevent viral infections in humans

Scientists from Duke-NUS Medical School and the Singapore General Hospital have discovered that T cells-white blood cells that can destroy harmful pathogens-can completely prevent viral infection, to an extent previously thought only possible due to neutralizing antibodies.

10 Jan 2025

Brain maturation delays linked to unhealthy eating behaviors in youth

More than half of 23-year-olds in a European study show restrictive, emotional or uncontrolled eating behaviors, according to new research led by the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London.

10 Jan 2025