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Study links epigenetic mechanism to placental blood vessel development

If the development of blood vessels in the placenta is impaired, fetal growth retardation may result. Scientists from the German Cancer Research Center (DKFZ) and the Mannheim Medical Faculty of Heidelberg University discovered that the correct development of functioning blood vessels in the mouse placenta is controlled epigenetically: One of the enzymes that modify gene activity using methyl groups is responsible.

15 Jan 2025

Semaglutide improves glycemic control with automated insulin delivery

Semaglutide combined with automated insulin delivery enhances glucose control in type 1 diabetes, lowering insulin requirements and aiding weight management.

15 Jan 2025

Pancreatic cancer insights: How pORG classifications predict survival and guide treatment

Researchers identify distinct molecular and immune profiles that impact the prognosis of patients with metastatic pancreatic ductal adenocarcinoma.

15 Jan 2025

GroceryDB helps shoppers spot ultra-processed foods

This open-source database utilizes machine learning to assess food processing, promoting nutrition security and informed consumer choices in the grocery market.

15 Jan 2025

Study reveals how bile acids impact immunotherapy in liver cancer

Immunotherapy is a modern approach to cancer treatment that uses a patient's own immune system to help fight tumors.

15 Jan 2025

Ultrasensitive ctDNA detection improves risk prediction in early-stage lung cancer

Ultrasensitive ctDNA detection with NeXT Personal shows 81% sensitivity in early-stage lung adenocarcinoma, improving prognostic accuracy and therapy guidance.

15 Jan 2025

New gene-editing treatment extends lifespan in mice with prion disease

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition.

15 Jan 2025

Researchers uncover new mutation mechanism driving cancer progression

Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 and 20, during times of rapid bone growth. Although rare, it has a significant impact on young people and their families as treatment can require surgery or amputation.

15 Jan 2025

Study unravels the links between obesity and cancer

Obesity, recognized as a complex and growing health issue, is associated with an increased risk of various cancers. A comprehensive review provides insights into the mechanisms linking obesity to cancer risk and discusses potential clinical implications.

15 Jan 2025

Exploring the psychological impact of "topical steroid withdrawal"

Painful skin and trouble sleeping are among the problems reported when tapering cortisone cream for atopic eczema. This has been shown by a study headed by the University of Gothenburg. Many users consider the problems to be caused by cortisone dependence.

15 Jan 2025

Unveiling the hidden benefit of bariatric surgery

Welcoming a newborn is something many couples dream of doing, but it can get complicated when conceiving becomes a roadblock. Infertility affects one in six people, but obesity can also be a problem. When diet and exercise aren't enough to lose weight, bariatric surgery can become an option. Yet a new national survey by Orlando Health finds that 56% of Americans do not know that bariatric surgery is an effective way to improve fertility.

14 Jan 2025

Gut microbes revealed as hidden drivers of aging and cellular decline

Gut microbiota-derived phenylacetylglutamine accelerates aging by driving cellular senescence through mitochondrial dysfunction and DNA damage, offering insights into therapeutic interventions for age-related decline.

14 Jan 2025

Proteomic mapping identifies biomarkers driving healthy aging and preventing chronic diseases

Scientists mapped the serum proteome longitudinally to uncover biomarkers linked to healthy aging and cardiometabolic diseases, revealing potential therapeutic targets.

14 Jan 2025

High-fat diet linked to impulsive behaviors and brain changes

Researchers examines how a high-fat diet modifies inhibitory control.

14 Jan 2025

AI reveals key follicle sizes to boost IVF success

Researchers utilize explainable artificial intelligence to identify follicle sizes important for relevant downstream clinical outcomes during assisted conception.

14 Jan 2025

Genetics, brain development, and mental health shape teen eating

Investigating the interplay of genetics, brain maturation, and mental health, this study reveals insights into adolescent eating behaviors and obesity risk.

14 Jan 2025

Gut microbiome dynamics reveal key factors influencing Enterobacteriaceae colonization

Analysis of gut microbiomes reveals co-colonization patterns and potential therapeutic targets against Enterobacteriaceae, addressing global health challenges.

14 Jan 2025

Time-restricted eating paired with exercise: Small changes, big impact

Study reveals that combining time-restricted eating with exercise results in small but significant reductions in fat mass and body fat percentage while preserving fat-free mass. However, variability in outcomes and short study durations highlight the need for further research.

13 Jan 2025

Morning coffee cuts health risks, but all-day sipping doesn’t

Moderate morning coffee consumption may lower all-cause and cardiovascular mortality risks, but coffee consumed throughout the day offers no similar benefits.

13 Jan 2025

UQ and Vaxxas win global prize to accelerate patch-based mRNA vaccine for COVID-19

The University of Queensland's BASE facility – within the Australian Institute for Bioengineering and Nanotechnology (AIBN) – and Brisbane-based biotechnology company Vaxxas have been announced as stage winners of a prestigious global prize to accelerate a patch-based mRNA vaccine for COVID-19.

13 Jan 2025