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New approach targets cell surface protein to treat leukemia and solid tumors

In 2021, research led by Ryan Flynn, MD, PhD, and his mentor, Nobel laureate Carolyn Bertozzi, PhD, opened a new chapter in biology, characterizing a new kind of player on the cell surface: glycoRNAs.

23 Apr 2025

New recommendations for the treatment of familial Mediterranean fever

In 2016, EULAR - The European Alliance of Associations for Rheumatology - published recommendations on the treatment of familial Mediterranean fever (FMF). Since then, new evidence has become available, so the recommendations have been reviewed and updated.

23 Apr 2025

Immune resilience identified as key to healthy aging and longevity

A study published in Aging Cell has identified immune resilience as a key driver of salutogenesis-the active process of promoting health and well-being.

23 Apr 2025

Muscle quality emerges as crucial factor in hip replacement recovery

Hip replacement surgery, or total hip arthroplasty (THA), can lessen pain and improve function in individuals with hip osteoarthritis, but some patients continue to experience long-term physical deficits-including muscle weakness, decreased functional mobility, and increased fall risk-after the procedure.

23 Apr 2025

DT-109 shows promise in treating atherosclerosis and liver disease

A drug candidate, previously successful at treating severe fatty liver disease, reduces atherosclerosis - a primary driver of cardiovascular death worldwide - in large mammals, a study suggests.

23 Apr 2025

Move more, think sharper: How physical activity boosts brain health in aging

A brisk walk, a splash of water aerobics, or even a light jog around the block – if your heart rate goes up then so too will your brain health according to new research from the University of South Australia.

23 Apr 2025

Mediterranean diet lowers breast cancer risk by 13%, postmenopausal women benefit most

A new meta-analysis of 31 observational studies finds that adherence to the Mediterranean diet is associated with a 13% lower risk of breast cancer in women, particularly among postmenopausal populations. The protective effect was strongest in Asian countries and in case-control study designs.

22 Apr 2025

Interferon regulatory factor 8 identified as key driver of liver fat buildup in NAFLD

Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance. Interferon regulatory factor 8 (IRF8) is well known for its roles in immune cell differentiation and tumor pathogenesis; however, its role in regulating glucose homeostasis and lipid metabolism remains unclear.

22 Apr 2025

UQ plays key role in a national effort to revolutionize prostate cancer treatment

The University of Queensland will play a key role in a national effort to revolutionize treatment for men with prostate cancer.

22 Apr 2025

Dogs offer more emotional support than most people, study finds

Study shows that dog-human relationships can be meaningfully evaluated using the same multidimensional social support scales applied to human relationships. Dogs were rated more positively than most human partners, especially in companionship, nurturance, and low conflict.

22 Apr 2025

Light-induced DNA detection technique enables rapid, ultra-sensitive genetic analysis

PCR genetic analysis has been in the spotlight since COVID-19, but light is now further facilitating PCR-free methods.

22 Apr 2025

Tulane researchers identify a potential new way to treat idiopathic pulmonary fibrosis

Researchers at Tulane University have identified a potential new way to treat idiopathic pulmonary fibrosis (IPF), a deadly and currently incurable lung disease that affects more than 3 million people worldwide.

22 Apr 2025

Study reveals how medulloblastoma spreads and grows on the leptomeninges

Researchers at Baylor College of Medicine, Texas Children's Hospital, the Hospital for Sick Children in Toronto and collaborating institutions reveal in Nature Cell Biology a strategy that helps medulloblastoma, the most prevalent malignant brain tumor in children, spread and grow on the leptomeninges, the membranes surrounding the brain and spinal cord.

22 Apr 2025

Can a plant-based diet help prevent breast cancer?

A case-control study in Iranian women found that higher adherence to a healthy plant-based diet significantly reduces breast cancer risk in postmenopausal women and those with a BMI under 25. In contrast, high intake of unhealthy plant-based foods raised risk in premenopausal women.

22 Apr 2025

Machine learning unlocks millions of safer CRISPR enzymes for gene editing

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions-but there is always room for improvement.

22 Apr 2025

Single psychedelic dose boosts long-term cognitive flexibility in mice

University of Michigan researchers have found that certain psychedelic compounds improve the brain’s ability to adapt and flexibly learn new concepts over long periods.

22 Apr 2025

Children’s mattresses expose sleepers to hidden chemical risks, study finds

A new study tested 16 children’s mattresses and found widespread contamination with harmful semivolatile organic compounds (SVOCs) like plasticizers and flame retardants. These chemicals can migrate into the sleeping environment, increasing children's risk of allergic and neurobehavioral effects.

22 Apr 2025

Study uncovers how prenatal stress leaves a molecular imprint on babies

A new study has uncovered how stress experienced by mothers during pregnancy leaves a molecular imprint on their babies—starting before birth.

22 Apr 2025

Disruption of sterol biosynthesis by prescription drugs: A hidden threat to brain development

A powerful editorial published today in Brain Medicine raises alarm about a previously overlooked threat to brain development and public health: the disruption of sterol biosynthesis by common prescription medications.

22 Apr 2025

Age and sex shape Alzheimer’s blood biomarkers, study finds

ESTHER study found that non-modifiable factors like age, sex, and APOE ε4 status significantly influence blood biomarker levels linked to Alzheimer’s disease. GFAP and NfL levels, in particular, showed strong age- and sex-related patterns, with GFAP levels rising faster in women.

22 Apr 2025