Molecular & Structural Biology

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Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity

Researchers identified the anti-SARS-CoV-2 function of phospholipid scramblase 1 (PLSCR1).

14 Jul 2023

Exploring the relationship between epigenetic aging and gut microbiome composition in physically fit men and women

Researchers investigate the relationship between the gut microbiome, physical fitness, and epigenetic aging in physically fit individuals.

14 Jul 2023

Cryo-EM reveals structure of key enzyme involved in protein production

Transfer RNAs (tRNAs) are among the most common types of RNA in a cell and are indispensable for protein production in all known organisms.

13 Jul 2023

Investigating the role of T-cell immunity in long COVID

Researchers investigates the persistence of symptoms and the immune response in patients recovering from COVID-19.

13 Jul 2023

Scientists track nanoscale processes of CRISPR-Cas complexes

Scientists at Leipzig University, in collaboration with colleagues at Vilnius University in Lithuania, have developed a new method to measure the smallest twists and torques of molecules within milliseconds.

12 Jul 2023

Study unveils an astounding array of unexplored protein folds in nature

A groundbreaking study has shed new light on the astonishing diversity of protein structures and their folds in nature.

12 Jul 2023

Novel protein modifies the cellular machinery responsible for producing cellulose in plant cells

Cellulose - an integral component of plant cell walls - is an important source of food, paper, textiles and biofuels, but how its creation is regulated within plant cells has remained unclear.

11 Jul 2023

New study shows circulating anti-insulin CD4 T cells reflect progression of anti-islet immunity

In a recent study published in Science Translational Medicine, researchers profile antigen-specific helper clusters of differentiation 4-positive (CD4+) T-lymphocytes to determine anti-islet autoimmunity among mice and humans.

9 Jul 2023

How B-cells and androgens contribute to the development of PCOS

Researchers evaluate the role of B-cell frequencies in the pathogenesis of polycystic ovary syndrome.

9 Jul 2023

Cryo-EM helps decode the molecular architecture of a neural transport protein

Using Cryo-EM, a powerful microscopy technique, researchers at IISc and collaborators have decoded the molecular architecture of a transporter protein controlling the movement of a key neurotransmitter.

6 Jul 2023

Scientists develop breakthrough approach to create artificial allosteric sites in protein complexes

According to a recently published research paper by a team of scientists, a groundbreaking approach has been developed to create artificial allosteric sites (where by binding an effector molecule, activity at the distal active site is regulated) in protein complexes.

6 Jul 2023

Researchers discover a molecular switch that regulates lipid metabolism in cells

Our body's fat metabolism plays a vital role in energy production in our body. A research team at the University of Basel, Switzerland, has discovered a molecular switch that regulates lipid metabolism in our cells.

3 Jul 2023

New AI tool can help track and identify complex fruit fly behavior

How can you tell if a fruit fly is hungry? Ask a computer. While that may sound like a bad dad joke, it's reality at Tulane University, where researchers have developed a new A.I. tool that can tell you if a fruit fly is hungry, sleepy or singing (yes, fruit flies sing).

30 Jun 2023

High-res insights into key bacterial enzyme could lead to development of new antibiotics

A team of scientists from around the globe, including those from Trinity College Dublin, has gained high-res structural insights into a key bacterial enzyme, which may help chemists design new drugs to inhibit it and thus suppress disease-causing bacteria.

30 Jun 2023

Katydid fossil found with internal organs intact

50 million years ago in what is now northwestern Colorado, a katydid died, sank to the bottom of a lake and was quickly buried in fine sediments, where it remained until its compressed fossil was recovered in recent years.

26 Jun 2023

Chickpea's secret history: How trade routes and migrations shaped the legume's genetic heritage

With its nutty flavor and dense nutrient profile, the humble chickpea has captivated palates and nourished civilizations for millennia.

23 Jun 2023

Analyzing the conformational dynamics of a human tRNA using high hydrostatic pressure

Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn.

23 Jun 2023

Deciphering a biochemical mechanism explains the center of protein factories

Based on genetic blueprints, individual amino acids are assembled into long amino acid chains, the proteins, in the protein factories of our cells, the ribosomes. Each newly formed protein starts with the amino acid methionine.

23 Jun 2023

UQ researchers uncover the structure of Langya virus' fusion protein

Researchers have shed light on how a highly infectious virus, that has recently transferred from animals to people, is able to enter human cells.

22 Jun 2023

Novel approach to multimodal aging clock for interpretable age prediction and target discovery

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 11, entitled, "Precious1GPT: multimodal transformer-based transfer learning for aging clock development and feature importance analysis for aging and age-related disease target discovery."

21 Jun 2023

Molecular & Structural Biology

Unveiling the key defender: PLSCR1 identified as a potent anti-SARS-CoV-2 factor in COVID-19 immunity

Exploring the relationship between epigenetic aging and gut microbiome composition in physically fit men and women

Cryo-EM reveals structure of key enzyme involved in protein production

Investigating the role of T-cell immunity in long COVID

Scientists track nanoscale processes of CRISPR-Cas complexes

Study unveils an astounding array of unexplored protein folds in nature

Novel protein modifies the cellular machinery responsible for producing cellulose in plant cells

New study shows circulating anti-insulin CD4 T cells reflect progression of anti-islet immunity

How B-cells and androgens contribute to the development of PCOS

Cryo-EM helps decode the molecular architecture of a neural transport protein

Scientists develop breakthrough approach to create artificial allosteric sites in protein complexes

Researchers discover a molecular switch that regulates lipid metabolism in cells

New AI tool can help track and identify complex fruit fly behavior

High-res insights into key bacterial enzyme could lead to development of new antibiotics

Katydid fossil found with internal organs intact

Chickpea's secret history: How trade routes and migrations shaped the legume's genetic heritage

Analyzing the conformational dynamics of a human tRNA using high hydrostatic pressure

Deciphering a biochemical mechanism explains the center of protein factories

UQ researchers uncover the structure of Langya virus' fusion protein

Novel approach to multimodal aging clock for interpretable age prediction and target discovery

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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