Molecular & Structural Biology

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DNAm measures of biological aging linked with neuropsychologically-validated cognitive decline in midlife

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 23, entitled, "DNA methylation-based measures of biological aging and cognitive decline over 16-years: preliminary longitudinal findings in midlife."

30 Dec 2022

New insights on the circadian clock of Drosophila melanogaster

The higher the temperatures, the faster physiological processes are. But there is an exception: the so-called circadian clock, which regulates the sleep-wake cycle in organisms.

30 Dec 2022

New insights into how working memory information may be held in mind

Between the time you read the Wi-Fi password off the café's menu board and the time you can get back to your laptop to enter it, you have to hold it in mind.

29 Dec 2022

Researchers design 3D structures made of DNA

Marvel at the tiny nanoscale structures emerging from research labs at Duke University and Arizona State University, and it's easy to imagine you're browsing a catalog of the world's smallest pottery.

23 Dec 2022

UC San Diego researchers rewrite the textbook on gene regulation

A fundamental principle of molecular biology governs how proteins are made within the cell, which happens in two stages called transcription and translation.

22 Dec 2022

DISCO-MS technology enables the study of diseases at their earliest stages

How can you trace a single diseased cell in an intact brain or a human heart? The search resembles looking for a needle in a haystack.

22 Dec 2022

Simple laser irradiation speeds up the detection of very small amounts of proteins

Protein detection based on antigen–antibody reaction is vital in early diagnosis of a wide range of diseases. How to effectively detect proteins, however, has frequently bedeviled researchers.

22 Dec 2022

Mutations responsible for common inherited heart condition corrected using CRISPR-Cas9 therapy

Using the CRISPR-Cas9 gene editing system, UT Southwestern researchers corrected mutations responsible for a common inherited heart condition called dilated cardiomyopathy (DCM) in human cells and a mouse model of the disease.

21 Dec 2022

Radiation damage to mature sperm cannot be repaired and is instead passed on to the offspring

Whether radiation exposure of fathers can have consequences on their children is one of the most long-standing questions in radiation biology.

21 Dec 2022

Research reveals how microorganisms found in the gut can worsen C. difficile infections

New research from the University of Virginia School of Medicine and collaborators reveals how microorganisms found in our guts can worsen dangerous C. difficile infections.

21 Dec 2022

New method uses artificial DNA to target and kill cancer cells

Researchers at the University of Tokyo have used artificial DNA to target and kill cancer cells in a completely new way.

21 Dec 2022

Study reveals both dark adapted and light-activated structures of a phytochrome

Scientist have revealed both dark adapted and light-activated structures of a red photosensory protein, phytochrome.

20 Dec 2022

Mild bee venom appears to be more usable for pharmacology

Honeybee venom has been used in traditional medicine for centuries as an anti-inflammatory. Only its main component, melittin, has been scientifically well researched.

20 Dec 2022

MGI’s DNBSEQ-T7* recognized for its ultra-high throughput and excellent accuracy

Thanks to high-throughput sequencing technologies, shotgun metagenomic methods were made possible and had effectively transformed microbiology.

19 Dec 2022

First cell-type specific multiomic study of the HIV brain

Researchers identify cell-type-specific differences in HIV integration sites in the brain.

19 Dec 2022

Smart molecular glue ensures the nucleus is correctly positioned for cell division

Researchers from Paul Scherrer Institute PSI and ETH Zurich have discovered how proteins in the cell can form tiny liquid droplets that act as a smart molecular glue.

19 Dec 2022

Cryo-electron microscopy reveals atomic structure of Staphylococcus epidermidis bacteriophage

Cryo-electron microscopy by University of Alabama at Birmingham researchers has exposed the structure of a bacterial virus with unprecedented detail.

18 Dec 2022

Study provides deeper insights into skeletal muscle aging

A new research paper was published on the cover of Aging (listed as "Aging (Albany NY)" by Medline/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 23, entitled, "Single nuclei profiling identifies cell specific markers of skeletal muscle aging, frailty, and senescence."

16 Dec 2022

Cryo-microscopy reveals high-resolution structure of monkeypox virus DNA polymerase holoenzyme

Using cryo-microscopy, researchers present a high-resolution structure of monkeypox virus DNA polymerase holoenzyme, a complex that plays a key role in the genome replication process of the virus.

16 Dec 2022

Study reveals subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinoma

Researchers from the Department of Clinical Oncology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered a novel subtype of Epstein-Barr Virus (EBV)-positive nasopharyngeal carcinoma (NPC) and EBV-associated immunosuppression in the tumor microenvironment (TME).

16 Dec 2022

Molecular & Structural Biology

DNAm measures of biological aging linked with neuropsychologically-validated cognitive decline in midlife

New insights on the circadian clock of Drosophila melanogaster

New insights into how working memory information may be held in mind

Researchers design 3D structures made of DNA

UC San Diego researchers rewrite the textbook on gene regulation

DISCO-MS technology enables the study of diseases at their earliest stages

Simple laser irradiation speeds up the detection of very small amounts of proteins

Mutations responsible for common inherited heart condition corrected using CRISPR-Cas9 therapy

Radiation damage to mature sperm cannot be repaired and is instead passed on to the offspring

Research reveals how microorganisms found in the gut can worsen C. difficile infections

New method uses artificial DNA to target and kill cancer cells

Study reveals both dark adapted and light-activated structures of a phytochrome

Mild bee venom appears to be more usable for pharmacology

MGI’s DNBSEQ-T7* recognized for its ultra-high throughput and excellent accuracy

First cell-type specific multiomic study of the HIV brain

Smart molecular glue ensures the nucleus is correctly positioned for cell division

Cryo-electron microscopy reveals atomic structure of Staphylococcus epidermidis bacteriophage

Study provides deeper insights into skeletal muscle aging

Cryo-microscopy reveals high-resolution structure of monkeypox virus DNA polymerase holoenzyme

Study reveals subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinoma

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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