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Why Astrazeneca and J&J’s vaccines, in use the world over, are still on hold in America

The World Health Organization greenlighted emergency use of AstraZeneca and Oxford's covid-19 vaccine this month, following in the steps of the United Kingdom, the European Union and others, who are already injecting it as quickly as possible into the masses.

26 Feb 2021

Single dose of Pfizer BioNTech vaccine can reduce asymptomatic SARS-CoV-2 infections

New data from Addenbrooke's Hospital in Cambridge suggests that a single dose of the Pfizer BioNTech vaccine can reduce by four-fold the number of asymptomatic SARS-CoV-2 infections.

26 Feb 2021

Researchers propose new mechanism to promote access to COVID-19 vaccines

Although the value of vaccines for COVID-19 may seem obvious, government action and investment in vaccines have not been commensurate with the enormous scale of benefits they offer, argue Juan Camilo Castillo and colleagues in this Policy Forum.

26 Feb 2021

FDA allows flexible storage and transportation conditions for Pfizer-Biontech COVID-19 vaccine

Today, the U.S. Food and Drug Administration announced that it is allowing undiluted frozen vials of the Pfizer-BioNTech COVID-19 Vaccine to be transported and stored at conventional temperatures commonly found in pharmaceutical freezers for a period of up to two weeks.

26 Feb 2021

Researchers examine effectiveness of Pfizer vaccine against COVID-19

A major study, conducted in collaboration with researchers from Harvard University, examined data on 600,000 vaccinated individuals in Israel, along with 600,000 matched unvaccinated controls.

26 Feb 2021

Extensive use of opioid agonists can considerably reduce drug-related deaths

New evidence that opioid agonists such as methadone and buprenorphine could substantially reduce drug-related deaths if more widely used in the community and prison, and for longer, has been published in Lancet Psychiatry.

25 Feb 2021

FDA approval provides targeted treatment option for patients with rare DMD mutation

Today, the U.S. Food and Drug Administration granted approval for Amondys 45 (casimersen) injection for the treatment of Duchenne muscular dystrophy (DMD) in patients who have a confirmed mutation of the DMD gene that is amenable to exon 45 skipping (Exons are pieces of DNA that provide information for making proteins in a person's genome).

25 Feb 2021

New approach can reduce unnecessary evaluations of swollen lymph nodes after COVID-19 vaccination

Swelling of lymph nodes in the armpit area is a normal response to COVID-19 vaccinations, but when they are seen on mammograms, they can be mistaken for nodes that are swollen because of cancer. In some cases, the nodes are biopsied to confirm they are not cancer.

25 Feb 2021

Long-term steroid treatment may not be necessary for kidney transplant patients

Long-term use of a medication used to treat kidney transplant patients may not be necessary in individuals with low-to-moderate risk of organ rejection, according to the results of a study led by a University of Cincinnati transplant researcher.

24 Feb 2021

UK and South African SARS-CoV-2 variants show higher binding affinity to host cell receptor

New research by a team of scientists at Stanford University School of Medicine in the U.S. found that both the UK and South African SARS-CoV-2 variants display tighter binding to the ACE2 receptor.

24 Feb 2021

New study highlights the value of recycling general anesthetic used in routine operations

New research has highlighted the value of recycling general anaesthetic used in routine operations.In the UK, healthcare accounts for more than five per cent of national greenhouse gas emissions, and as much as 10 per cent in the US.

24 Feb 2021

Knowledge gaps about side effects may increase medication nonadherence among older people

Older people correctly ascertained basic information such as dosage and duration of use for more than 70% of the medications they were prescribed, regardless of whether their physician explained it during an office visit.

24 Feb 2021

New glioma-targeted nano-therapeutic offers a potential treatment for glioblastomas

With a survival rate of only five years, the most common and aggressive form of primary brain tumor, glioblastoma multiforme, is notoriously hard to treat using current regimens that rely on surgery, radiation, chemotherapy, and their combinations.

24 Feb 2021

New microneedle patches for delivery of psychedelic pharmaceuticals

Although one may think of psychedelic pharmaceuticals as being dangerous and detrimental, scientists have been conducting experiments and clinical trials on some of them and have obtained positive results when testing them for medical use.

23 Feb 2021

Could rotavirus vaccine platforms aid in the immunization campaign against SARS-CoV-2?

The study began with the generation of recombinant (r)SA11 rotaviruses, into which segment 7 modified RNAs were introduced. These encoded sequences for the non-structural protein NSP3 and some parts of the viral spike.

23 Feb 2021

Propranolol can be used to treat cerebral cavernous malformations

Propranolol, a drug that is efficacious against infantile haemangiomas ("strawberry naevi", resembling birthmarks), can also be used to treat cerebral cavernous malformations, a condition characterized by misshapen blood vessels in the brain and elsewhere.

23 Feb 2021

Three decades-old antibiotics could offer an alternative to opioid-based painkillers

Three decades-old antibiotics administered together can block a type of pain triggered by nerve damage in an animal model, UT Southwestern researchers report.

23 Feb 2021

An overview of spike protein antigen COVID-19 vaccine candidates

A new paper in the journal Reviews in Medical Virology provides a perspective on current vaccine development strategies and tools, which may allow the production of safe and effective vaccines.

22 Feb 2021

Novel SARS-CoV-2 vaccine utilizes recombinant spike protein with PIKA adjuvant

The primary aim of any vaccine is to stimulate immune functions and confer long-lasting protection. A paper recently uploaded to the preprint server bioRxiv by Tong et al. (17th Feb 2021) describes a novel vaccine utilizing PIKA adjuvant and recombinant spike proteins against COVID-19 disease that promises the generation of potent neutralization antibodies, which potentially support immune responses for years.

21 Feb 2021

Interval between doses of Oxford COVID-19 vaccine can be safely extended to 3 months, suggests study

A 3-month interval between doses of the Oxford COVID-19 vaccine results in higher vaccine efficacy than a 6-week interval, with the first dose offering 76% protection in the 3 months between doses.

20 Feb 2021

Pharmaceutical News

Why Astrazeneca and J&J’s vaccines, in use the world over, are still on hold in America

Single dose of Pfizer BioNTech vaccine can reduce asymptomatic SARS-CoV-2 infections

Researchers propose new mechanism to promote access to COVID-19 vaccines

FDA allows flexible storage and transportation conditions for Pfizer-Biontech COVID-19 vaccine

Researchers examine effectiveness of Pfizer vaccine against COVID-19

Extensive use of opioid agonists can considerably reduce drug-related deaths

FDA approval provides targeted treatment option for patients with rare DMD mutation

New approach can reduce unnecessary evaluations of swollen lymph nodes after COVID-19 vaccination

Long-term steroid treatment may not be necessary for kidney transplant patients

UK and South African SARS-CoV-2 variants show higher binding affinity to host cell receptor

New study highlights the value of recycling general anesthetic used in routine operations

Knowledge gaps about side effects may increase medication nonadherence among older people

New glioma-targeted nano-therapeutic offers a potential treatment for glioblastomas

New microneedle patches for delivery of psychedelic pharmaceuticals

Could rotavirus vaccine platforms aid in the immunization campaign against SARS-CoV-2?

Propranolol can be used to treat cerebral cavernous malformations

Three decades-old antibiotics could offer an alternative to opioid-based painkillers

An overview of spike protein antigen COVID-19 vaccine candidates

Novel SARS-CoV-2 vaccine utilizes recombinant spike protein with PIKA adjuvant

Interval between doses of Oxford COVID-19 vaccine can be safely extended to 3 months, suggests study

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