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UK public health authorities review early data on the effectiveness of Pfizer and AstraZeneca COVID-19 vaccines

A team of UK scientists has recently evaluated the effectiveness of the Pfizer (BNT162b2) and AstraZeneca (ChAdOx1) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The findings reveal that both vaccines are effective in significantly reducing SARS-CoV-2 infection in older adults and providing long-term protection.

3 Mar 2021

Obesity may reduce COVID-19 vaccine efficacy, say researchers

A startling indicates that obesity may reduce the immune response to the current COVID-19 vaccines, along with other factors like age and sex. This could have significant implications for vaccination strategies in obese people.

3 Mar 2021

Delayed second dose strategy with mRNA vaccines may reduce COVID-19 mortality, say researchers

An interesting new preprint shows that even if countries are forced to delay the second dose of the current vaccines administered against SARS-CoV-2, to arrest the ongoing COVID-19 pandemic, the cumulative mortality would still fall significantly.

3 Mar 2021

Semaglutide drug also helps diabetic patients lose body weight, shows study

A drug approved for diabetes has now been shown to also help patients with diabetes lose on average 10 percent of their body weight, UT Southwestern reports in a landmark international study.

3 Mar 2021

Placebo-like effects may explain the benefits of psychedelic drugs

Positive psychological effects associated with taking small doses of psychedelic drugs are likely the result of users' expectations, suggests a study published today in eLife.

3 Mar 2021

Study provides detailed insight into neural mechanisms underlying placebo effects

A large proportion of the benefit that a person gets from taking a real drug or receiving a treatment to alleviate pain is due to an individual's mindset, not to the drug itself.

2 Mar 2021

Moderna vaccine reduces viral spread by at least 60 percent, finds study

An interesting new study by researchers at Harvard T.H. Chan School of Public Health in the U.S. suggests that the currently used Moderna vaccine reduces viral shedding by about 60%.

2 Mar 2021

Biological activity-based modeling offers a new approach for drug discovery

Assessing a drug compound by its activity, not simply its structure, is a new approach that could speed the search for COVID-19 therapies and reveal more potential therapies for other diseases.

2 Mar 2021

Researchers study the digestion process of drug-loaded DNA nanostructures in real time

DNA nanotechnology - the research field using DNA molecules as building material - has developed rapidly during recent years and enabled the construction of increasingly complex nanostructures.

2 Mar 2021

Hydroxychloroquine should not be used to prevent COVID-19, says WHO expert panel

The anti-inflammatory drug hydroxychloroquine should not be used to prevent infection in people who do not have covid-19, say a WHO Guideline Development Group (GDG) panel of international experts in The BMJ today.

2 Mar 2021

Comparative analysis of SARS-CoV-2 antivirals leads to new potential treatment for COVID-19

Scientists compared the in vitro efficacy and cytotoxicity profiles of PF-00835231 and remdesivir in two human model systems for SARS-CoV-2 infection.

1 Mar 2021

Single-dose of BNT162b2 vaccine may not be protective without prior SARS-CoV-2 infection

A new study by researchers at Imperial College London, UK, discusses the effect of a vaccine dose, specifically the BNT162b2 candidate (also known as the ‘Pfizer-BioNTech’ vaccine), on neutralizing antibody titers in individuals who have already been infected with the virus.

1 Mar 2021

Could SARS-CoV-2 antibody tests before first vaccine dose help increase coverage and protection?

A new study by scientists in the UK raises the very useful hypothesis that natural infection may help spread the vaccine thinner without loss of efficacy.

1 Mar 2021

FDA issues EUA for third COVID-19 vaccine

Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the third vaccine for the prevention of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

1 Mar 2021

Pfizer-BioNTech SARS-CoV-2 vaccine effective for wide range of Covid-19–related outcomes

The Pfizer-BioNTech mRNA vaccine was shown to be 95% effective in preventing severe COVID-19 infection in clinical trials. However, given that the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread and evolve into several concerning variants, it remained unknown how the vaccine would respond in a real-life setting.

1 Mar 2021

Bacteria use slimy strategy to defeat antibiotics that fight cystic fibrosis

University of Montana researchers and their partners have discovered a slimy strategy used by bacteria to defeat antibiotics and other drugs used to combat infections afflicting people with cystic fibrosis. The research was published Feb. 23 in the journal Cell Reports.

27 Feb 2021

FDA to finalize the issuance of emergency use authorization for vaccine distribution

Following today's positive advisory committee meeting outcome regarding the Janssen Biotech Inc. COVID-19 Vaccine, the U.S. Food and Drug Administration has informed the sponsor that it will rapidly work toward finalization and issuance of an emergency use authorization.

27 Feb 2021

FDA approves Nulibry to reduce risk of death caused by rare genetic, metabolic disorder

Today, the U.S. Food and Drug Administration approved Nulibry (fosdenopterin) for injection to reduce the risk of death due to Molybdenum Cofactor Deficiency Type A, a rare, genetic, metabolic disorder that typically presents in the first few days of life, causing intractable seizures, brain injury and death.

27 Feb 2021

Researchers develop an electroceutical for preterm labor detection and treatment

Preterm labor comprises 12.7% of all pregnancies. Although the overall rate of pregnancy is decreasing, the occurrence of premature birth due to preterm labor in south korea has been increasing over the past 7 years.

26 Feb 2021

Statin use associated with reduction in mortality of patients with severe COVID-19

People who took statins to lower cholesterol were approximately 50% less likely to die if hospitalized for COVID-19, a study by physicians at Columbia University Vagelos College of Physicians and Surgeons and NewYork-Presbyterian has found.

26 Feb 2021

Pharmaceutical News

UK public health authorities review early data on the effectiveness of Pfizer and AstraZeneca COVID-19 vaccines

Obesity may reduce COVID-19 vaccine efficacy, say researchers

Delayed second dose strategy with mRNA vaccines may reduce COVID-19 mortality, say researchers

Semaglutide drug also helps diabetic patients lose body weight, shows study

Placebo-like effects may explain the benefits of psychedelic drugs

Study provides detailed insight into neural mechanisms underlying placebo effects

Moderna vaccine reduces viral spread by at least 60 percent, finds study

Biological activity-based modeling offers a new approach for drug discovery

Researchers study the digestion process of drug-loaded DNA nanostructures in real time

Hydroxychloroquine should not be used to prevent COVID-19, says WHO expert panel

Comparative analysis of SARS-CoV-2 antivirals leads to new potential treatment for COVID-19

Single-dose of BNT162b2 vaccine may not be protective without prior SARS-CoV-2 infection

Could SARS-CoV-2 antibody tests before first vaccine dose help increase coverage and protection?

FDA issues EUA for third COVID-19 vaccine

Pfizer-BioNTech SARS-CoV-2 vaccine effective for wide range of Covid-19–related outcomes

Bacteria use slimy strategy to defeat antibiotics that fight cystic fibrosis

FDA to finalize the issuance of emergency use authorization for vaccine distribution

FDA approves Nulibry to reduce risk of death caused by rare genetic, metabolic disorder

Researchers develop an electroceutical for preterm labor detection and treatment

Statin use associated with reduction in mortality of patients with severe COVID-19

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Shaping the future of lab automation through AI and robotics

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