Pharmaceutical News

RSS

Drugs used to treat HIV and hepatitis B could be repurposed to prevent type 2 diabetes

A group of drugs used to treat HIV and hepatitis B could be repurposed to prevent type 2 diabetes, a new study suggests.

23 Sep 2020

Cardiovascular adverse events linked to hydroxychloroquine and chloroquine

As the antimalarial drugs hydroxychloroquine and chloroquine have drawn attention as potential therapies for COVID-19 and are being widely used off-label, it's now more important than ever to have a thorough assessment of the safety of these medications.

23 Sep 2020

HIV drugs cause immune-system changes that can improve resistance to viral infections

Drugs currently used to keep the HIV virus in check also cause immune-system changes that might make humans better able to resist viral infections – but might also cause harmful inflammation, according to a study published today in Cell Reports Medicine.

23 Sep 2020

New book sheds light on addiction to psychoactive drugs

Cold Spring Harbor Laboratory Press (CSHLP) announced the publication of Addiction, 2e, now available on its website in ebook and hardcover formats.

23 Sep 2020

BCG vaccine may offer protection against COVID-19, shows study

While scientists race to develop and test a vaccine effective against SARS-CoV-2, the virus that causes COVID-19, recent studies have indicated that countries with widespread BCG vaccination appear to be weathering the pandemic better than their counterparts.

22 Sep 2020

New data shows alarming surge in opioid-related overdoses during COVID-19

In a paper published Friday by the Journal of the American Medical Association, Virginia Commonwealth University researchers released data showing an alarming surge in opioid-related overdoses during the COVID-19 pandemic.

22 Sep 2020

Drug used to treat breast and ovarian cancer can transform treatment for prostate cancer

A drug used to treat breast and ovarian cancer can extend the lives of some men with prostate cancer and should become a new standard treatment for the disease, concludes a major trial which is set to change clinical practice.

21 Sep 2020

In vitro testing suggests effective novel drug combinations for SARS-CoV-2

A recent study published on the preprint server bioRxiv* in September 2020 shows the value of drug combinations to enhance the therapeutic and preventive efficacy of such repositioned drugs in standard antiviral therapy.

20 Sep 2020

New polygenic risk score to help predict the odds of drugs causing liver damage

The ancient Romans studied the livers of sacrificial animals to read omens and make prophesies. Now researchers at Tokyo Medical and Dental University and Takeda-CiRA program along with a world-wide team of collaborators, have devised a polygenic risk score (PRS) based on liver genomics that can predict the likelihood of medications causing liver damage.

19 Sep 2020

Researchers design transdisciplinary course to prepare future clinicians in opioid crisis

Opioid use disorder and overdose have reached unprecedented levels around the world. In the United States, remediation of pain is one of the most common reasons American adults seek healthcare.

18 Sep 2020

Study highlights need for scientific, pharmaceutical standards for developing live biotherapeutic products

The Pharmabiotic Research Institute (PRI), Europe's only regulatory expertise centre for the development of microbiome-based drug products, has announced the publication of a review titled "Live biotherapeutic products: the importance of a defined regulatory framework".

18 Sep 2020

Researchers identify biomarkers that predict patient’s response to metformin treatment

Metformin is the first-line drug that can lower blood sugar levels in type 2 diabetes patients. One third of patients do not respond to metformin treatment and 5 per cent experience serious side effects, which is the reason many choose to stop medicating.

18 Sep 2020

Study shows huge asymmetry in cancer clinical trials in different countries

Access to cancer medicines is highly unequal across Europe both for new drugs in development because of uneven access to clinical trials and for currently approved drugs due to huge disparities in healthcare spending by different countries, according to results from studies presented at ESMO 2020.

18 Sep 2020

Scientists investigate how psychedelic drugs interact with brain cells at the molecular level

Psychedelic drugs such as LSD, psilocybin, and mescaline cause severe and often long-lasting hallucinations, but they show great potential in treating serious psychiatric conditions, such as major depressive disorder.

18 Sep 2020

Study finds wide variation in levels and anti-tumor effectiveness of a common cancer drug

When used to manage infections, the drug itraconazole is generally given at a single, fixed dose to all patients.

17 Sep 2020

PPI use linked to worse outcomes in urothelial cancer patients treated with atezolizumab

Proton pump inhibitor (PPI) use was associated with worse outcomes in patients with urothelial cancer treated with the immunotherapeutic atezolizumab (Tecentriq), compared with patients who did not use PPIs.

17 Sep 2020

IU School of Medicine wins $12.3 million grant for research into opioid addiction treatment

Researchers at Indiana University School of Medicine are testing use of tezampanel, a novel antagonist at glutamate receptors that could treat opioid withdrawal syndrome and other addictions and mental illnesses.

17 Sep 2020

Combined use of three drugs linked with lower lung cancer incidence and mortality

Combined use of aspirin, statins, and metformin is associated with decreased lung cancer incidence and mortality, according to a study published in the Journal of Thoracic Oncology.

17 Sep 2020

Ceftazidime flagged as a potential inhibitor of the SARS-COV-2 virus

After screening more than 3,500 FDA-approved drugs and small molecules, researchers at the Chinese Academy of Sciences found that ceftazidime, an antibiotic approved for use in treating pneumonia, binds to the receptors that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to in human cells.

17 Sep 2020

Study: Pleotropic drugs can have both favorable and unfavorable effects on cell growth, survival

The cover for issue 37 of Oncotarget features Figure 7, "The combination of romidepsin and KU60019 is synergistic in a xenograft model of MCL," by Scotto, et al. which reported that the antiproliferative effect induced by histone deactylase inhibitors is associated with the up-regulated expression of the cyclin-dependent kinase inhibitor p21.

17 Sep 2020

Pharmaceutical News

Drugs used to treat HIV and hepatitis B could be repurposed to prevent type 2 diabetes

Cardiovascular adverse events linked to hydroxychloroquine and chloroquine

HIV drugs cause immune-system changes that can improve resistance to viral infections

New book sheds light on addiction to psychoactive drugs

BCG vaccine may offer protection against COVID-19, shows study

New data shows alarming surge in opioid-related overdoses during COVID-19

Drug used to treat breast and ovarian cancer can transform treatment for prostate cancer

In vitro testing suggests effective novel drug combinations for SARS-CoV-2

New polygenic risk score to help predict the odds of drugs causing liver damage

Researchers design transdisciplinary course to prepare future clinicians in opioid crisis

Study highlights need for scientific, pharmaceutical standards for developing live biotherapeutic products

Researchers identify biomarkers that predict patient’s response to metformin treatment

Study shows huge asymmetry in cancer clinical trials in different countries

Scientists investigate how psychedelic drugs interact with brain cells at the molecular level

Study finds wide variation in levels and anti-tumor effectiveness of a common cancer drug

PPI use linked to worse outcomes in urothelial cancer patients treated with atezolizumab

IU School of Medicine wins $12.3 million grant for research into opioid addiction treatment

Combined use of three drugs linked with lower lung cancer incidence and mortality

Ceftazidime flagged as a potential inhibitor of the SARS-COV-2 virus

Study: Pleotropic drugs can have both favorable and unfavorable effects on cell growth, survival

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

Latest News