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Evotec collaborates with CENTOGENE to develop compounds to treat rare genetic diseases

CENTOGENE today announced that Evotec AG and CENTOGENE AG entered into a global strategic collaboration agreement for joint drug discovery projects, developing compounds to treat rare genetic diseases.

27 Aug 2018

Aspirin appears to cause major bleeds and have no effect on cancers

Aspirin prevented serious vascular events in patients with diabetes who did not already have cardiovascular disease, but it caused almost as many major bleeds and there was no effect on cancers.

27 Aug 2018

Study: 1 in 12 children taking multiple medications at risk of drug-drug interactions

According to new research from the University of Illinois at Chicago, about one in five children regularly use prescription medications, and nearly one in 12 of those children are at risk for experiencing a harmful drug-drug interaction.

27 Aug 2018

Study finds traces of marijuana in breast milk up to six days after use

With the legalization of marijuana in several states, increased use for both medicinal and recreational purposes has been documented in pregnant and breastfeeding women.

27 Aug 2018

Oral anticoagulant use after hospital discharge may offer protection from non-fatal blood clots

The use of an oral anticoagulant medicine in medically ill patients for 45 days following their discharge from the hospital reduces the rate of non-fatal symptomatic blood clots with no impact on fatal blood clots, according to late breaking results from the MARINER trial presented today in a Hot Line Session at ESC Congress 2018 and published in The New England Journal of Medicine.

27 Aug 2018

ARRIVE study assesses impact of daily aspirin on heart attacks, strokes

The jury is still out on whether people at moderate risk of a first heart attack or stroke should take daily aspirin to lower their risk, according to late breaking results from the ARRIVE study presented today in a Hot Line Session at ESC Congress 2018 and with simultaneous publication in the Lancet.

27 Aug 2018

Weight loss pill Lorcaserin found to have low cardiovascular risk

Weight loss pills have been discovered and then withdrawn from the market because of the risks that they pose to the heart. Some of them have raised the risk of heart attacks, suicides, heart valve problems significantly and have been thus banned.

27 Aug 2018

$Entresto drug can be initiated early and safely in heart failure patients with reduced ejection fraction$

Entresto drug can be initiated early and safely in heart failure patients with reduced ejection fraction

Data from the TRANSITION study presented today at the European Society of Cardiology Congress in Munich, Germany has shown that Entresto® can be initiated early and safely in a wide range of heart failure patients with reduced ejection fraction who have been stabilized after hospitalization due to an acute heart failure episode.

25 Aug 2018

Peptilogics held pre-IND meeting with FDA to develop PLG0206 for treating prosthetic joint infections

Peptilogics, a development stage company utilizing its innovative peptide platform to treat multidrug-resistant bacterial infections, today announced it recently held a pre-Investigational New Drug (pre-IND) meeting with the U.S. Food and Drug Administration to discuss the regulatory pathway for the development of PLG0206 for the treatment of prosthetic joint infections.

25 Aug 2018

Patients with blood pressure must start treatment with two drugs as a single pill

A single pill with two drugs could transform blood pressure treatment, according to the 2018 European Society of Cardiology and European Society of Hypertension Guidelines on arterial hypertension published online today in European Heart Journal, and on the ESC website.

25 Aug 2018

HU researchers develop new biological drug that may cure acute myeloid leukemia

Acute myeloid leukemia is one of the most aggressive cancers. While other cancers have benefited from new treatments, there has been no encouraging news for most leukemia patients for the past 40 years. Until now.

24 Aug 2018

Drug used to treat amoebic dysentery may block journey of rabies virus in nerves

To successfully infect its host, the rabies virus must move from the nerve ending to the nerve cell body where it can replicate.

24 Aug 2018

Podcast: KHN’s ‘What the Health?’ Opioids, epipens and health funding

The Senate is still working, well into August - something it hasn't done in years — and it’s debating the funding bill for the Department of Health and Human Services.

24 Aug 2018

Wound healing work presented at the RCP Innovation in Medicine Conference 2018 by Neem Biotech

Neem Biotech recently attended the Royal College of Physicians’ Innovation in Medicine Conference 2018 where Neem presented their data around wound-relevant biofilms.

From Neem Biotech 23 Aug 2018

Individual hypertensive responses to antibiotics may vary depending on genetic makeup and gut bacteria

Individual variations in genetic makeup and gut bacteria may explain the different effects of antibiotics on blood pressure, a new rat study suggests. The findings are published ahead of print in Physiological Genomics.

23 Aug 2018

Eisai: EC approves marketing of LENVIMA as first-line treatment for hepatocellular carcinoma

Eisai Co., Ltd. and Merck & Co., Inc., Kenilworth N.J., U.S.A., known as MSD outside of the United States and Canada, announced today that the European Commission has granted a marketing authorization for the oral receptor tyrosine kinase inhibitor LENVIMA (lenvatinib mesylate) as a single agent for the first-line treatment of adult patients with advanced or unresectable hepatocellular carcinoma who have received no prior systemic therapy.

23 Aug 2018

PETA reports show that animal research failed to benefit human health

Animal research has failed to benefit human health, wasted limited public research funds, misled clinicians, and harmed countless animals unnecessarily, finds a new report by PETA scientists Emily Trunnell, Ph.D., and Frances Cheng, Ph.D.

23 Aug 2018

FDA approves first drug for treatment of rare disease affecting the cornea

The U.S. Food and Drug Administration today approved the first drug, Oxervate (cenegermin), for the treatment of neurotrophic keratitis, a rare disease affecting the cornea (the clear layer that covers the colored portion of the front of the eye).

23 Aug 2018

Common ADHD drug may cause adverse psychotic side effects

In the scientific article recently published in Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, Erica Ramstad and others reviewed the existing evidence between various psychotic symptoms such as hallucinations, problems with concentration or anxiety with methylphenidate, a drug commonly prescribed as a treatment for attention deficit hyperactivity disorder and narcolepsy.

22 Aug 2018

FDA release Pilot COA Compendium to promote patient-focused drug development

Value in Health, the official journal of ISPOR, announced today the publication of a scoping review of the US Food and Drug Administration Pilot Clinical Outcome Assessment Compendium.

22 Aug 2018

Pharmaceutical News

Evotec collaborates with CENTOGENE to develop compounds to treat rare genetic diseases

Aspirin appears to cause major bleeds and have no effect on cancers

Study: 1 in 12 children taking multiple medications at risk of drug-drug interactions

Study finds traces of marijuana in breast milk up to six days after use

Oral anticoagulant use after hospital discharge may offer protection from non-fatal blood clots

ARRIVE study assesses impact of daily aspirin on heart attacks, strokes

Weight loss pill Lorcaserin found to have low cardiovascular risk

Entresto drug can be initiated early and safely in heart failure patients with reduced ejection fraction

Peptilogics held pre-IND meeting with FDA to develop PLG0206 for treating prosthetic joint infections

Patients with blood pressure must start treatment with two drugs as a single pill

HU researchers develop new biological drug that may cure acute myeloid leukemia

Drug used to treat amoebic dysentery may block journey of rabies virus in nerves

Podcast: KHN’s ‘What the Health?’ Opioids, epipens and health funding

Wound healing work presented at the RCP Innovation in Medicine Conference 2018 by Neem Biotech

Individual hypertensive responses to antibiotics may vary depending on genetic makeup and gut bacteria

Eisai: EC approves marketing of LENVIMA as first-line treatment for hepatocellular carcinoma

PETA reports show that animal research failed to benefit human health

FDA approves first drug for treatment of rare disease affecting the cornea

Common ADHD drug may cause adverse psychotic side effects

FDA release Pilot COA Compendium to promote patient-focused drug development

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

Edoardo Fabini

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