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Nearly one in three opioid prescriptions in the US not justified, finds analysis

According to a nationwide analysis of physician visit records conducted by a team of researchers at Harvard Medical School and the RAND Corporation, nearly 30 percent of the outpatient opioid prescriptions made out in the United States do not have documented justification for their use.

12 Sep 2018

Inhaled form of high blood pressure drug has potential to treat anxiety, pain

An inhaled form of a high blood pressure medication has potential to treat certain types of anxiety as well as pain, according to a new study by the Centre for Addiction and Mental Health.

11 Sep 2018

ImmusanT receives JDRF T1D Fund to develop novel vaccine candidate for type 1 diabetes

ImmusanT, Inc., a clinical stage company that is leveraging its Epitope-Specific Immuno-Therapy™ platform to translate and deliver first-in-class peptide-based immune therapies to people living with autoimmune diseases, today announced that it has received an investment from the JDRF T1D Fund, a venture philanthropy fund exclusively devoted to finding and funding the best type 1 diabetes commercial opportunities.

11 Sep 2018

Mechanically ventilated patients treated with vasopressor may develop ICU-related weakness

At least 25 percent of critically ill patients who receive mechanical ventilation in intensive care units develop muscular weakness severe enough to impair their quality of life.

11 Sep 2018

Study aims to understand role of clopidogrel in patients with cardiovascular disease

Platelet inhibition with aspirin is the cornerstone of medical therapy for coronary artery disease. In the era of percutaneous coronary intervention with drug-eluting stents, dual anti-platelet therapy with the addition of clopidogrel became the mainstay of therapy.

11 Sep 2018

Researchers discuss clinical application of bivalirudin in interventional cardiovascular procedures

Anticoagulation is imperative to reduce the incidence of thrombotic complications in patients undergoing percutaneous interventional cardiovascular procedures; however, this is at the expense of increased risk of bleeding.

11 Sep 2018

Anticoagulant use in East Asian patients with nonvalvular atrial fibrillation

In the current issue of Cardiovascular Innovations and Applications (Volume3,Number 2, 2018, pp. 215-226(12); DOI: https://doi.org/10.15212/CVIA.2017.0033 Chang-Sheng Ma from the Department of Cardiology, Beijing AnZhen Hospital, Capital Medical University, Beijing, China considers the use of direct oral anticoagulants for prevention of stroke and systemic embolic events in East Asian patients with nonvalvular atrial fibrillation.

11 Sep 2018

Medical cannabis provides relief across dozens of health symptoms, study shows

Utilizing new mobile application technology, researchers at The University of New Mexico found that medical cannabis provides immediate symptom relief across dozens of health symptoms with relatively minimal negative side effects.

11 Sep 2018

FDA approves Cassipa sublingual film for maintenance treatment of opioid dependence

The U.S. Food and Drug Administration today approved Cassipa (buprenorphine and naloxone) sublingual film (applied under the tongue) for the maintenance treatment of opioid dependence.

7 Sep 2018

Researchers develop new generation of pain medications

Researchers from Charité - Universitätsmedizin Berlin and the Zuse Institute Berlin have developed a new generation of pain medications.

7 Sep 2018

NCCN updates Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets

Exelixis, Inc. today announced that the National Comprehensive Cancer Network updated its Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets.

7 Sep 2018

EC approves update of INVOKANA and VOKANAMET labeling to include changes to indication statement

The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the European Commission has granted approval to update the INVOKANA® and VOKANAMET® labeling to include changes to the indication statement for the treatment of adults with insufficiently controlled type 2 diabetes mellitus as an adjunct to diet and exercise.

7 Sep 2018

Daytime sleepiness found to be a potential risk factor for Alzheimer’s disease

Older adults who frequently report feeling sleepy during the day are three times more likely to develop Alzheimer's in later life, according to a new study.

7 Sep 2018

Insulin’s high cost leads to deadly rationing

Diabetic ketoacidosis is a terrible way to die. It’s what happens when you don’t have enough insulin. Your blood sugar gets so high that your blood becomes highly acidic, your cells dehydrate, and your body stops functioning.

7 Sep 2018

Mayo Clinic collaborates with seven hospitals to establish not-for-profit generic drug company

Mayo Clinic joins a coalition of seven hospitals in launching Civica Rx, a not-for-profit generic drug company that will help patients by addressing shortages and high prices of lifesaving medications. The company, which is organized as a Delaware nonstock, not-for-profit corporation, will be headquartered in Utah.

7 Sep 2018

Single dose of influenza drug can shorten duration of illness, study reveals

A single dose of a new influenza drug can significantly shorten the duration of the illness in teens and adults, according to a study published in the prestigious New England Journal of Medicine.

6 Sep 2018

Free online Heart Age Test reveals likelihood of having a heart attack

PHE is running a campaign to encourage people to take a free online Heart Age Test to see whether they are at an increased risk of having a heart attack.

6 Sep 2018

Autism biomarker may aid early diagnoses

A newly discovered group of blood metabolites could act as a biomarker to accelerate the diagnosis of autism spectrum disorder.

6 Sep 2018

BeiGene collaborates with SpringWorks to evaluate new combinational therapy for solid tumors

BeiGene, Ltd., a commercial-stage biopharmaceutical company focused on developing and commercializing innovative molecularly-targeted and immuno-oncology drugs for the treatment of cancer, and SpringWorks Therapeutics, a clinical-stage rare disease and oncology company focused on sourcing and developing innovative treatments for underserved patient populations, announced today that the companies have entered into a global clinical collaboration agreement to evaluate the safety, tolerability and preliminary efficacy of combining BeiGene's investigational RAF dimer inhibitor, lifirafenib and SpringWorks Therapeutics' investigational MEK inhibitor, PD-0325901, in patients with advanced solid tumors.

6 Sep 2018

New system accelerates discovery of chemical compounds that inhibit enzyme implicated in cancers

Researchers at the National Center for Advancing Translational Sciences, part of the National Institutes of Health, have developed a system to accelerate the discovery of chemical compounds that inhibit an enzyme implicated in a number of cancers.

6 Sep 2018

Pharmaceutical News

Nearly one in three opioid prescriptions in the US not justified, finds analysis

Inhaled form of high blood pressure drug has potential to treat anxiety, pain

ImmusanT receives JDRF T1D Fund to develop novel vaccine candidate for type 1 diabetes

Mechanically ventilated patients treated with vasopressor may develop ICU-related weakness

Study aims to understand role of clopidogrel in patients with cardiovascular disease

Researchers discuss clinical application of bivalirudin in interventional cardiovascular procedures

Anticoagulant use in East Asian patients with nonvalvular atrial fibrillation

Medical cannabis provides relief across dozens of health symptoms, study shows

FDA approves Cassipa sublingual film for maintenance treatment of opioid dependence

Researchers develop new generation of pain medications

NCCN updates Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets

EC approves update of INVOKANA and VOKANAMET labeling to include changes to indication statement

Daytime sleepiness found to be a potential risk factor for Alzheimer’s disease

Insulin’s high cost leads to deadly rationing

Mayo Clinic collaborates with seven hospitals to establish not-for-profit generic drug company

Single dose of influenza drug can shorten duration of illness, study reveals

Free online Heart Age Test reveals likelihood of having a heart attack

Autism biomarker may aid early diagnoses

BeiGene collaborates with SpringWorks to evaluate new combinational therapy for solid tumors

New system accelerates discovery of chemical compounds that inhibit enzyme implicated in cancers

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

Edoardo Fabini

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