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SMA treatment may be effective even if started in children seven months and older

A drug shown to be effective in the treatment of babies with the rare muscle-wasting disease spinal muscular atrophy may be effective for muscle control even when treatment is started in children seven months and older, according to a study published in the August 29, 2018, online issue of Neurology, the medical journal of the American Academy of Neurology. Previous studies focused on children younger than seven months old.

30 Aug 2018

Researchers take major step forward in finding safe and non-addictive pain killer

With the support of the National Institute on Drug Abuse, scientists at Wake Forest School of Medicine have been working to find a safe, non-addictive pain killer to help fight the current opioid crisis in this country.

30 Aug 2018

Scientists discover potential treatment for Alzheimer’s disease

Scientists discovered a modified version of an immune cell receptor called a toll-like receptor that could be used as a treatment for Alzheimer’s disease.

29 Aug 2018

Ketamine's acute antidepressant effect requires opioid system activation, finds study

A new study appearing online today from the American Journal of Psychiatry finds that ketamine's acute antidepressant effect requires opioid system activation, the first time that a receptor site has been shown in humans to be necessary for any antidepressant's mechanism of action.

29 Aug 2018

Clinical trials needed to inform doctors, parents on prescribing cannabinoids for Canadian children

Canadian parents use unregulated cannabinoids for seizure control in children with neurologic conditions like epilepsy, and clinical trials are needed to inform doctors and parents on prescribing, according to a commentary in CMAJ.

29 Aug 2018

Study explores effects of combined, isolated use of cannabis and nicotine on the brain

Researchers at the Center for BrainHealth® at the University of Texas at Dallas investigated the effects on the brain of concurrent cannabis and nicotine use, versus the use of solely cannabis and solely nicotine.

29 Aug 2018

Drug used for chest pain does not decrease chance of first occurrence of ventricular arrhythmias

A clinical trial of more than 1,000 patients with implantable cardioverter defibrillators found that the drug ranolazine was safe but didn't significantly decrease the likelihood of the first occurrence of ventricular tachycardia, ventricular fibrillation or death in this high-risk population.

29 Aug 2018

New wearable sensor helps patients with bipolar disorder safely monitor lithium levels

Patients living with bipolar disorder and depression will soon be able to use a unique wearable sensor to safely monitor their lithium drug levels.

29 Aug 2018

FDA warns consumers and pet owners not to use drug products made by King Bio

The Food and Drug Administration is warning consumers and pet owners not to use drug products, including homeopathic drug products, made by King Bio Inc., Asheville, N.C., and labeled as Dr. King's, as these products may pose a safety risk to people (especially infants, children, pregnant women and those with compromised immune systems), as well as pets due to high levels of microbial contamination identified at the manufacturing site.

29 Aug 2018

Blood pressure lowering therapy and statins continue to improve survival in patients with hypertension

Blood pressure and cholesterol lowering drugs continue to improve survival in patients with hypertension after more than a decade, according to late breaking results from the ASCOT Legacy study presented at ESC Congress 2018 and published in The Lancet.

28 Aug 2018

Combined oral anticoagulant and antiplatelet therapy linked to poor prognosis in atrial fibrillation

Combined oral anticoagulant and antiplatelet therapy is associated with a worse prognosis than anticoagulation alone in newly diagnosed atrial fibrillation patients without a clear indication for antiplatelets, according to late breaking results from the GARFIELD-AF registry presented today at ESC Congress 2018.

28 Aug 2018

Blood pressure medication slows enlargement of the aorta in patients with Marfan syndrome

Treatment with a drug to lower blood pressure slows enlargement (dilatation) of the aorta in children and young adults with Marfan syndrome, according to late breaking results from the AIMS trial presented today in a Hot Line Session at ESC Congress 2018.

28 Aug 2018

Experts to discuss concepts, methods of gender medicine and their impact on oncology

Gender-based approaches to studying and treating disease have remained largely unexplored in medical oncology, despite the field's growing interest in precision medicine and accumulating evidence that sex is a major factor in disease risk and response to treatment.

28 Aug 2018

Researchers create candidate drugs with potential to curb smoking

Washington State University researchers have created more than a dozen candidate drugs with the potential to curb smokers' desire for nicotine by slowing how it is broken down in the body. The researchers hope the substances can help people reduce their consumption of tobacco, if not quit altogether.

28 Aug 2018

Most commonly prescribed drugs to primary care patients are not often tested

Drugs most commonly prescribed to patients seen by primary care physicians are not often tested in the patients who go to these clinics, where most people receive their care, say investigators at Georgetown University Medical Center and Yale School of Medicine.

28 Aug 2018

Daily use of aspirin does not reduce occurrence of major cardiovascular events, finds ARRIVE trial

The role of aspirin in preventing a first heart attack or stroke among people at moderate risk of heart disease remains unclear.

28 Aug 2018

Amphetamine regimen does not improve post-stroke motor recovery

A pilot clinical trial exploring the benefit of d-amphetamine combined with physical therapy for stroke patients found no evidence that the regimen improved post-stroke motor recovery.

27 Aug 2018

Study shows new options to lower heart disease risk in people with diabetes

A drug used to manage diabetes may reduce heart disease and death in people with diabetes regardless of their cholesterol levels and whether they are on a statin therapy, suggests a new analysis of the LEADER trial.

27 Aug 2018

Antithrombin drug does not reduce risk of myocardial infarction, stroke in heart failure patients

The antithrombin drug rivaroxaban does not reduce the risk of a composite endpoint of survival, myocardial infarction and stroke after an episode of worsening heart failure in patients with heart failure, sinus rhythm, and coronary artery disease, according to late breaking results from the COMMANDER HF trial presented today in a Hot Line Session at ESC Congress 2018 and with simultaneous publication in NEJM.

27 Aug 2018

Some breast cancers can prevent their own spread

Scientists have discovered a mechanism by which people with advanced breast cancer do not experience metastasis and live normal lives.

27 Aug 2018

Pharmaceutical News

SMA treatment may be effective even if started in children seven months and older

Researchers take major step forward in finding safe and non-addictive pain killer

Scientists discover potential treatment for Alzheimer’s disease

Ketamine's acute antidepressant effect requires opioid system activation, finds study

Clinical trials needed to inform doctors, parents on prescribing cannabinoids for Canadian children

Study explores effects of combined, isolated use of cannabis and nicotine on the brain

Drug used for chest pain does not decrease chance of first occurrence of ventricular arrhythmias

New wearable sensor helps patients with bipolar disorder safely monitor lithium levels

FDA warns consumers and pet owners not to use drug products made by King Bio

Blood pressure lowering therapy and statins continue to improve survival in patients with hypertension

Combined oral anticoagulant and antiplatelet therapy linked to poor prognosis in atrial fibrillation

Blood pressure medication slows enlargement of the aorta in patients with Marfan syndrome

Experts to discuss concepts, methods of gender medicine and their impact on oncology

Researchers create candidate drugs with potential to curb smoking

Most commonly prescribed drugs to primary care patients are not often tested

Daily use of aspirin does not reduce occurrence of major cardiovascular events, finds ARRIVE trial

Amphetamine regimen does not improve post-stroke motor recovery

Study shows new options to lower heart disease risk in people with diabetes

Antithrombin drug does not reduce risk of myocardial infarction, stroke in heart failure patients

Some breast cancers can prevent their own spread

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Building Bridges to Scalable Allogeneic Cell Therapy

Edoardo Fabini

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