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Wnt secretion inhibitors may reduce renal fibrosis

Renal fibrosis or the scarring of kidneys, following an injury, reduces their function and can cause kidney disease to progressively worsen.

25 Mar 2016

Lancet experts call for evidence-based approach to drug policy

Fifty years of drug policies aimed at restricting and criminalizing drug use and minor possession have had serious detrimental effects on the health, wellbeing and human rights of drug users and the wider public, according to a major new report by The Lancet and Johns Hopkins University in the US

25 Mar 2016

Penn chemists find potential ways to use methane in pharmaceuticals, value-added substances

Methane is the world's most abundant hydrocarbon. It's the major component of natural gas and shale gas and, when burned, is an effective fuel. But it's also a major contributor to climate change, with 24 times greater potency as a greenhouse gas than carbon dioxide.

25 Mar 2016

Incretin-based drugs do not increase risk of heart failure

Incretin-based drugs, a type of medication used to treat type 2 diabetes, do not increase the risk of being hospitalized for heart failure relative to commonly used combinations of oral anti-diabetic drugs, according to a new study published in the New England Journal of Medicine.

25 Mar 2016

Restrictions to opioid prescription block their use for safe, effective pain relief

Opioids are very effective for treating some types of pain, such as cancer pain and postoperative pain, but not for other kinds of pain like chronic low back pain. An increase in the number of opioid-related deaths among addicts has led to the current movement to restrict opioid prescribing by state and federal authorities.

25 Mar 2016

FDA issues draft guidance to support development of approved ADF opioids

The U.S. Food and Drug Administration today issued a draft guidance intended to support industry in their development of generic versions of approved opioids with abuse-deterrent formulations (ADF) while ensuring that generic ADF opioids are no less abuse-deterrent than the brand-name drug.

25 Mar 2016

TSRI scientists develop new process to synthesize naturally occurring compound phorbol

In a landmark feat of chemical synthesis, scientists at The Scripps Research Institute have developed a 19-step process for making the naturally occurring compound phorbol in the laboratory, in quantities that are useful for pharmaceutical research.

24 Mar 2016

Researchers develop versatile building blocks that could be useful in pharmaceutical research

Researchers in the Doyle lab at Princeton have developed a direct cross-coupling reaction to produce nitrogen-containing compounds called 1,2-dihydropyridines, versatile building blocks that are highly useful in pharmaceutical research.

24 Mar 2016

New project aims to prevent complications from drug usage

If a patient is ill and takes drugs for that illness, these drugs often lead to further illnesses and complications. This affects millions of people throughout the world.

24 Mar 2016

Study shows fish oil supplements make no significant difference to muscle growth

The effect of fish oil supplements on muscle growth has been investigated by a team of Stirling academics, revealing the tablets do not give gym-goers an advantage in the weight room.

24 Mar 2016

Chinese medicines may contain hazardous chemicals

Chinese medicines are manufactured and distributed all over the world. Many people perceive them as natural, even benign and with few side effects, but regulation of human medicines fluctuates widely in different countries.

24 Mar 2016

Anticonvulsant medication gabapentin effectively reduces common complication of PONV

The anticonvulsant medication gabapentin—already a useful part of strategies to control pain after surgery—also effectively reduces the common complication of postoperative nausea and vomiting (PONV), reports a study in Anesthesia & Analgesia.

23 Mar 2016

FDA announces required class-wide safety labeling changes for IR opioid pain medications

In a continuing effort to educate prescribers and patients about the potential risks related to opioid use, the U.S. Food and Drug Administration today announced required class-wide safety labeling changes for immediate-release (IR) opioid pain medications. Among the changes, the FDA is requiring a new boxed warning about the serious risks of misuse, abuse, addiction, overdose and death.

23 Mar 2016

Cinqair (reslizumab) approved for treatment of severe asthma

The U.S. Food and Drug Administration today approved Cinqair (reslizumab) for use with other asthma medicines for the maintenance treatment of severe asthma in patients aged 18 years and older. Cinqair is approved for patients who have a history of severe asthma attacks (exacerbations) despite receiving their current asthma medicines.

23 Mar 2016

Targeted therapies suppress T cell activity that could actually help fight tumors

In many cases, targeted therapies for cancer are preferred as treatments over chemotherapy and surgery because they attack and kill cancer cells with specific tumor-promoting mutations while sparing healthy, normal cells that do not express these mutations.

23 Mar 2016

DAA medication could lead to revolution in hepatitis C treatment

The cost of treating hepatitis C virus (HCV) could be cut up to 50 percent if mathematical models are used to predict when patients can safely stop taking direct-acting antiviral (DAA) medication, according to a new study by researchers at Loyola University Health System and Loyola University Chicago

23 Mar 2016

New research links antibiotic use before age 2 to childhood obesity

While early antibiotic use has been associated with a number of rare long-term health consequences, new research links antibiotics to one of the most important and growing public health problems worldwide -- obesity.

23 Mar 2016

Antipsychotic medications may not be effective in preventing delirium in hospitalized patients

A recent review of the medical literature does not support the use of antipsychotic medications for preventing or treating delirium in hospitalized patients.

23 Mar 2016

Subcutaneous injection of raltegravir can protect against vaginal HIV transmission

Vaginal transmission accounts for the majority of new HIV infections worldwide. Forms of pre-exposure prophylaxis (PrEP) such as vaginal gels and vaginal rings designed to prevent HIV transmission have encountered poor efficacy in human trials due to problems with adherence.

22 Mar 2016

Tiny gel slivers open way to personalised cancer treatment targeting particular tumour

They look like small, translucent gems but these tiny 'gel' slivers hold the world of a patient's tumour in microcosm ready for trials of anti-cancer drugs to find the best match between treatment and tumour.

22 Mar 2016

Pharmaceutical News

Wnt secretion inhibitors may reduce renal fibrosis

Lancet experts call for evidence-based approach to drug policy

Penn chemists find potential ways to use methane in pharmaceuticals, value-added substances

Incretin-based drugs do not increase risk of heart failure

Restrictions to opioid prescription block their use for safe, effective pain relief

FDA issues draft guidance to support development of approved ADF opioids

TSRI scientists develop new process to synthesize naturally occurring compound phorbol

Researchers develop versatile building blocks that could be useful in pharmaceutical research

New project aims to prevent complications from drug usage

Study shows fish oil supplements make no significant difference to muscle growth

Chinese medicines may contain hazardous chemicals

Anticonvulsant medication gabapentin effectively reduces common complication of PONV

FDA announces required class-wide safety labeling changes for IR opioid pain medications

Cinqair (reslizumab) approved for treatment of severe asthma

Targeted therapies suppress T cell activity that could actually help fight tumors

DAA medication could lead to revolution in hepatitis C treatment

New research links antibiotic use before age 2 to childhood obesity

Antipsychotic medications may not be effective in preventing delirium in hospitalized patients

Subcutaneous injection of raltegravir can protect against vaginal HIV transmission

Tiny gel slivers open way to personalised cancer treatment targeting particular tumour

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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