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Very few patients use FDA-approved medications for weight loss, new study suggests

Despite guidelines that advocate the use of weight loss medications to treat obesity, and the availability of FDA approved medications, very few patients use this treatment option, a new study suggests. The results will be presented Sunday, April 3, at ENDO 2016, the annual meeting of the Endocrine Society, in Boston.

5 Apr 2016

Inhalable form of Ambrisentan drug could offer faster-acting treatment option for pulmonary edema

In a new study, researchers show an aerosolized, inhalable form of the drug Ambrisentan could offer a faster-acting treatment option for pulmonary edema, a life-threatening condition in which fluid accumulates in the lungs. Pulmonary edema is a significant risk for anyone spending time at high altitudes, and also affects people with chronic conditions including congestive heart failure and sickle cell anemia.

5 Apr 2016

ADHD stimulant drugs may lower bone density in children and adolescents

Children and teenagers who take stimulant drugs to treat attention-deficit hyperactivity disorder (ADHD) may have lower bone density than their peers who do not take these medications, a new study finds.

5 Apr 2016

Combining aromatase inhibitors with growth hormone may help short adolescent boys grow taller

Aromatase inhibitors, when used for up to three years in combination with growth hormone, may effectively and safely help very short adolescent boys grow taller, new research suggests. The study results will be presented Sunday, April 3, at ENDO 2016, the annual meeting of the Endocrine Society in Boston.

4 Apr 2016

Increased consumption of antibiotics in childhood may lead to adolescent prediabetes

Young children who take antibiotics may disrupt their gut's microbial ecosystem and be more likely to develop prediabetes in adolescence, new research from Greece reports. The study results will be presented in a poster Sunday, April 3, at ENDO 2016, the annual meeting of the Endocrine Society, in Boston.

4 Apr 2016

Oral Salmonella-based vaccine could prevent Type 1 diabetes

A combined vaccine therapy including live Salmonella is a safe and effective way to prevent diabetes in mice and may point to future human therapies, a new study finds. The results will be on Sunday, April 3, at ENDO 2016, the annual meeting of the Endocrine Society, in Boston.

4 Apr 2016

Cambridge Pharmaceutical Cryo-EM Consortium formed by FEI, five pharmaceutical companies, the Medical Research Council and the University of Cambridge

FEI (NASDAQ: FEIC) has partnered with five pharmaceutical companies: Astex Pharmaceuticals, AstraZeneca, GlaxoSmithKline, Heptares Therapeutics, and UCB; the Medical Research Council Laboratory of Molecular Biology (MRC-LMB); and the University of Cambridge’s Nanoscience Centre, to form the “Cambridge Pharmaceutical Cryo-EM Consortium,” which is the first of its kind worldwide.

From Thermo Fisher Scientific – Electron Microscopy Solutions 4 Apr 2016

Janssen announces CHMP positive opinion for use of paliperidone palmitate 3-monthly injection for schizophrenia treatment

Janssen UK announced today that the Committee for Medicinal Products for Human Use (CHMP) has adopted a positive opinion recommending the use of paliperidone palmitate 3-monthly injection for the maintenance treatment of schizophrenia in the European Union.

4 Apr 2016

CHMP recommends conditional marketing authorisation for Janssen’s daratumumab

Janssen-Cilag announced today that the Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended the granting of a conditional marketing authorisation for first-in-class CD38 immunotherapy daratumumab in the European Union.

4 Apr 2016

Seasonal trivalent influenza vaccination during pregnancy may guard against stillbirth

Seasonal influenza vaccination may guard against stillbirth, a new study published in Clinical Infectious Diseases and available online suggests. Researchers in Western Australia analyzed data from nearly 60,000 births that occurred during the southern hemisphere's 2012 and 2013 seasonal influenza epidemics, and found that women who received the trivalent influenza vaccine during pregnancy were 51 percent less likely to experience a stillbirth than unvaccinated mothers.

2 Apr 2016

U of S-led researchers develop novel class of compounds for effective cancer treatment

A novel class of compounds developed by a University of Saskatchewan-led research team could yield more effective and less toxic chemotherapy drugs to treat cancer.

2 Apr 2016

NTU researchers make breakthrough to tackle growing concern of antibiotic resistance

Scientists at Nanyang Technological University, Singapore have discovered that antibiotics can continue to be effective if bacteria's cell-to-cell communication and ability to latch on to each other are disrupted.

2 Apr 2016

Novel method uses light-activated nanodrug to help fight antibiotic-resistant infections

A research team led by University of Arkansas chemist Jingyi Chen and University of Arkansas for Medical Sciences microbiologist Mark Smeltzer has developed an alternative therapeutic approach to fighting antibiotic-resistant infections.

2 Apr 2016

Research suggests ibuprofen does not increase bleeding risk after plastic surgery

Patients are often instructed not to take ibuprofen and other nonsteroidal anti-inflammatory drugs before or after surgery because of increased bleeding risk. But available evidence suggests that ibuprofen does not increase the risk of bleeding after plastic surgery procedures, according to a research review in the April issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

2 Apr 2016

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

Several new immunotherapeutic antibodies that inhibit checkpoint receptors on T cells to restimulate the immune system to target tumors have been approved to treat advanced stage lung cancer and melanoma; however, only 20 percent of lung cancer patients show a response to these agents.

2 Apr 2016

GHIT Fund invests in two innovative malaria eradication tools

The Global Health Innovative Technology Fund (GHIT Fund) announced today that it’s investing US$1,383,785 in a pair of innovative malaria eradication tools—a vaccine that could block transmission of two species of the deadly disease and a rapid field test that can reveal a malaria infection in minutes.

1 Apr 2016

Experimental Ebola vaccine may help fight latest flare-up in Guinea

Hundreds of people who may have been in contact with 8 individuals infected with Ebola virus in Guinea’s southern prefectures of Nzérékoré and Macenta have been vaccinated with the experimental Ebola vaccine in a bid to contain the latest flare-up of Ebola.

1 Apr 2016

FDA approves Defitelio to treat hepatic veno-occlusive disease in adults, children

The U.S. Food and Drug Administration today approved Defitelio (defibrotide sodium) to treat adults and children who develop hepatic veno-occlusive disease (VOD) with additional kidney or lung abnormalities after they receive a stem cell transplant from blood or bone marrow called hematopoietic stem cell transplantation (HSCT).

31 Mar 2016

Researchers design more effective version of FDA-approved epilepsy drug with fewer side effects

Researchers at the University of Pittsburgh School of Medicine and Arts & Sciences have designed a more effective version of an FDA-approved epilepsy drug with the potential for fewer side effects, according to a study published on March 22 in Molecular Pharmacology. The experimental agent also could prove to be a treatment for tinnitus and other disorders caused by volatile neural signaling.

31 Mar 2016

Two recently discovered compounds show promise for treating Ewing sarcoma in children

Two recently discovered compounds have shown promise in preclinical studies for treating Ewing sarcoma, a rare cancer that predominantly affects children and adolescents.

31 Mar 2016

Pharmaceutical News

Very few patients use FDA-approved medications for weight loss, new study suggests

Inhalable form of Ambrisentan drug could offer faster-acting treatment option for pulmonary edema

ADHD stimulant drugs may lower bone density in children and adolescents

Combining aromatase inhibitors with growth hormone may help short adolescent boys grow taller

Increased consumption of antibiotics in childhood may lead to adolescent prediabetes

Oral Salmonella-based vaccine could prevent Type 1 diabetes

Cambridge Pharmaceutical Cryo-EM Consortium formed by FEI, five pharmaceutical companies, the Medical Research Council and the University of Cambridge

Janssen announces CHMP positive opinion for use of paliperidone palmitate 3-monthly injection for schizophrenia treatment

CHMP recommends conditional marketing authorisation for Janssen’s daratumumab

Seasonal trivalent influenza vaccination during pregnancy may guard against stillbirth

U of S-led researchers develop novel class of compounds for effective cancer treatment

NTU researchers make breakthrough to tackle growing concern of antibiotic resistance

Novel method uses light-activated nanodrug to help fight antibiotic-resistant infections

Research suggests ibuprofen does not increase bleeding risk after plastic surgery

HDAC inhibitors could improve activity of immunotherapeutic antibodies in lung cancer patients

GHIT Fund invests in two innovative malaria eradication tools

Experimental Ebola vaccine may help fight latest flare-up in Guinea

FDA approves Defitelio to treat hepatic veno-occlusive disease in adults, children

Researchers design more effective version of FDA-approved epilepsy drug with fewer side effects

Two recently discovered compounds show promise for treating Ewing sarcoma in children

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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