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EC approves Regeneron’s EYLEA for treatment of wet AMD

Regeneron Pharmaceuticals, Inc. today announced that EYLEA (aflibercept) Injection has been approved by the European Commission for the treatment of patients with neovascular (wet) age-related macular degeneration (wet AMD).

27 Nov 2012

Routine HIV testing can reduce illness and death across Canada

Offering routine HIV testing to the general population rather than only to high-risk individuals will significantly reduce illness and death, argues Dr. Julio Montaner and coauthors in an editorial in CMAJ (Canadian Medical Association Journal).

27 Nov 2012

Chemotherapy can induce brain changes that may affect concentration and memory

Chemotherapy can induce changes in the brain that may affect concentration and memory, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

27 Nov 2012

Experimental flu vaccine technique could reduce time needed to develop new shots for humans

"An experimental vaccine based on a molecule related to DNA protects animals against influenza and may one day offer an ultra-rapid way to develop new shots for humans, German scientists reported on Sunday," Reuters reports.

27 Nov 2012

Viewpoints: Sen. Corker's plan to avoid the 'fiscal cliff'; Romney's brave attempt to deal with health entitlements; Fixing the drug shortage

I have shared with House and Senate leaders as well as the White House a 242-page bill that, along with other agreed-upon cuts that are to be enacted, would produce $4.5 trillion in fiscal reforms and replace sequestration.

27 Nov 2012

Antifibrinolytics inhibit glycine receptor activity in the brain and cause seizures

Antifibrinolytic drugs are frequently used to prevent blood loss during surgery, but sometimes cause convulsive seizures. In this issue of the Journal of Clinical Investigation, researchers led by Beverly Orser at the University of Toronto investigated the molecular mechanisms that underlie this side effect.

27 Nov 2012

Researchers discover molecular basis for potential cancer preventive effects of vitamin D

A team of researchers at McGill University have discovered a molecular basis for the potential cancer preventive effects of vitamin D. The team, led by McGill professors John White and David Goltzman, of the Faculty of Medicine's Department of Physiology, discovered that the active form of vitamin D acts by several mechanisms to inhibit both the production and function of the protein cMYC.

26 Nov 2012

Avermectin family of drugs shows promise against TB

A well-established family of drugs used to treat parasitic diseases is showing surprising potential as a therapy for tuberculosis (TB), according to new research from University of British Columbia microbiologists.

26 Nov 2012

AMITIZA for treatment of chronic constipation now available in Japan

Sucampo Pharmaceuticals, Inc. and Abbott today announced the availability of AMITIZA (lubiprostone) in Japan, a prescription medicine for the treatment of chronic constipation not caused by organic diseases. AMITIZA was approved by the Ministry of Health, Labor and Welfare (MHLW) in Japan in June.

26 Nov 2012

mRNA vaccines offer protection against influenza A virus infections in various animal models

CureVac GmbH, a clinical stage biopharmaceutical company developing a new class of therapies and vaccines based on mRNA, and the German Federal Research Institute for Animal Health, Friedrich-Loeffler-Institute (FLI), Germany, today announced that mRNA vaccines (RNActive) based on the company's RNA technology platform have the potential to provide effective protection against infectious diseases.

26 Nov 2012

Lymphopenia driven diseases and the orphan drug industry: an interview with Damian Marron, CEO of Cytheris

Lymphopenia is when you lack the T cells of your immune system. T cells are very important for controlling infection. Probably the most known cause of lymphopenia is HIV.

23 Nov 2012

Study to discover exactly how intravenous immune globulin treatments work

Immune globulin replacement began decades ago as a treatment for patients who could not make their own protective antibodies, but has proven to have much broader benefits than originally expected.

22 Nov 2012

Bowel cancer and GIST patients could benefit from novel oral drug

Two phase 3 trials, published in The Lancet, have shown that a novel oral drug called regorafenib could offer survival benefits to people with bowel (colorectal) cancer or gastrointestinal stromal tumour (GIST) following failure of existing treatments.

22 Nov 2012

TGF-betaR inhibitors may counter drug resistance in cancer patients with MED12 mutations

Cancer therapies often have short-lived benefits due to the emergence of genetic mutations that cause drug resistance. A key gene that determines resistance to a range of cancer drugs has been reported in a study published by Cell Press November 21st in the journal Cell.

22 Nov 2012

Single dose of Medicago's vaccine could offer cross-protection against flu

Researchers recently found that a single dose of a vaccine being developed by Medicago, Inc., a publicly traded biopharmaceutical company, could protect against not only the avian influenza (H5N1) strain it was designed for, but also another H5N1 strain and a strain of a different flu subtype, called H2N2.

22 Nov 2012

Tirofiban effectively prevents strokes in high risk patients

Scientists may have discovered a new way to prevent strokes in high risk patients, according to research from the University of Warwick and University Hospitals Coventry and Warwickshire (UHCW).

22 Nov 2012

Microbiologists discover how the spread of antibiotic resistance works in pneumococcus

Antibiotic resistance results from bacteria's uncanny ability to morph and adapt, outwitting pharmaceuticals that are supposed to kill them. But exactly how the bacteria acquire and spread that resistance inside individuals carrying them is not well-established for most bacterial organisms.

22 Nov 2012

AMFm should continue, improvements should be explored

The "grand experiment" of the Affordable Medicines Facility-malaria (AMFm) -- a pilot program that aims to get artemisinin-based combination therapies (ACTs) into rural areas of several African nations -- "seems likely to end, its successes underrated and potential improvements not yet explored," a Nature editorial says.

22 Nov 2012

Iridoid synthase can make powerful chemicals from catnip to vinblastine

Scientists have discovered an enzyme used in nature to make powerful chemicals from catnip to a cancer drug, vinblastine. The discovery opens up the prospect of producing these chemicals cheaply and efficiently.

22 Nov 2012

OB-GYN group calls for over-the-counter birth control pills

In an attempt to reduce unintended pregnancies that cost the nation an estimated $11.1 billion a year, the nation's largest group of obstetricians and gynecologists said Tuesday that oral contraceptives should be available without a prescription.

22 Nov 2012

Pharmaceutical News

EC approves Regeneron’s EYLEA for treatment of wet AMD

Routine HIV testing can reduce illness and death across Canada

Chemotherapy can induce brain changes that may affect concentration and memory

Experimental flu vaccine technique could reduce time needed to develop new shots for humans

Viewpoints: Sen. Corker's plan to avoid the 'fiscal cliff'; Romney's brave attempt to deal with health entitlements; Fixing the drug shortage

Antifibrinolytics inhibit glycine receptor activity in the brain and cause seizures

Researchers discover molecular basis for potential cancer preventive effects of vitamin D

Avermectin family of drugs shows promise against TB

AMITIZA for treatment of chronic constipation now available in Japan

mRNA vaccines offer protection against influenza A virus infections in various animal models

Lymphopenia driven diseases and the orphan drug industry: an interview with Damian Marron, CEO of Cytheris

Study to discover exactly how intravenous immune globulin treatments work

Bowel cancer and GIST patients could benefit from novel oral drug

TGF-betaR inhibitors may counter drug resistance in cancer patients with MED12 mutations

Single dose of Medicago's vaccine could offer cross-protection against flu

Tirofiban effectively prevents strokes in high risk patients

Microbiologists discover how the spread of antibiotic resistance works in pneumococcus

AMFm should continue, improvements should be explored

Iridoid synthase can make powerful chemicals from catnip to vinblastine

OB-GYN group calls for over-the-counter birth control pills

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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